Science

Corvelva Updates Scientific Vaccine Purity Safety Testing

Grazie  mille a la nostra amici a Corvelva.Corvelva vaccingate

Click here to see this full report at the Corvelva site.

We want to take stock of the situation together with you. Eight months have passed since July 2018 and in these length of time we have achieved extremely satisfying results. We have presented a research program and regarding the vaccines analysis we are able to make a point of reference, with the objectives achieved, those being finalised and those only planned for now.

To begin with, the analyses of 2 compounds for each vaccine have been verified by means of standards, using certified control standards with a concentration in the order of micrograms / mL. The compounds we have chosen are among those known for their critical hazard profile. We are talking about a cumulative quantity, a total amount of those recognized as identities and those to be identified, which can be estimated within the order of 50 micrograms / mL, in contrast to the EMA / FDA guidelines.

These tests have given positive results, therefore they fully confirm the analysis method! The contaminations observed are probably due to different and variable manufacturing process’ phenomena and topics. What has been observed in the course of the studies is an “inter-batches” variation of the composition, which makes us assume that there are some steps along the whole product manufacturing process that are difficult to control.

Such analyses have allowed us to achieve the following steps:

  • Conformity assessment of composition as outlined in the vaccine datasheet
  • Screening for chemical and protein/peptide contaminations, as well as those deriving from genetic material
  • Confirmatory study of chemical and protein target compounds through con standard certificates of inspection

The following vaccines have been submitted to an initial screening:

Continue reading "Corvelva Updates Scientific Vaccine Purity Safety Testing" »


Scurrilous, Misleading Attack On Prof Christopher Exley By The Sunday Times

image from www.keele.ac.ukby John Stone

An attack on leading aluminium toxicity expert Christopher Exley in the Sunday Times yesterday begins with the false claim in the title that his funding has been halted. This seems like a blatant attempt to mislead: what was halted the week before last after political pressure was a Go Fund Me page for supporting his research, while the Keele University website has remained open for donations. Another false claim is that there were no controls for his autism brain study. While there were no "normal" brains in the study there were comparisons:

"The aluminium content of brain tissues from donors with a diagnosis of ASD was extremely high (Table 1). While there was significant inter-tissue, inter-lobe and inter-subject variability the mean aluminium content for each lobe across all 5 individuals was towards the higher end of all previous (historical) measurements of brain aluminium content, including iatrogenic disorders such as dialysis encephalopathy [13][15][16][17][18][19]. All 4 male donors had significantly higher concentrations of brain aluminium than the single female donor. We recorded some of the highest values for brain aluminium content ever measured in healthy or diseased tissues in these male ASD donors including values of 17.10, 18.57 and 22.11 μg/g dry wt. (Table 1). What discriminates these data from other analyses of brain aluminium in other diseases is the age of the ASD donors. Why, for example would a 15 year old boy have such a high content of aluminium in their brain tissues? There are no comparative data in the scientific literature, the closest being similarly high data for a 42 year old male with familial Alzheimer’s disease (fAD) [19]."

Professional concerns about the use of aluminium adjuvants in vaccine products are by no means unique to Prof Exley and colleagues.

The professional attack in the report is led by Andrew Pollard who is said to be a professor of "paediatric infection": it does not mention Pollard's manifold roles as leader of Oxford Vaccine Group, which develops vaccines with the industry (mostly containing aluminium), as chair of the Joint Committee on Vaccination and Immunisation which recommends vaccines to the British schedule, as leading adviser to the British and European licensing agencies, and board member of the Jenner Vaccine Foundation. In July 2017 he also called in the Guardian newspaper for compulsory vaccination without disclosing any of these roles. Real investigative journalists might be asking what research Pollard has ever undertaken into the safety of aluminium adjuvants in vaccine products which he helps develop, recommend and license?

John Stone is British editor of Age of Autism


DeVos Wants To Cut What?

Scissors giantThe Secretary of Education Betsy DeVos included cuts to Special Olympics funding in her budget proposal. For those of us with special needs kids, there are few places where we can feel even a little bit welcome, let alone at home. For many families, Special Olympics provides a refuge, not just a place to compete in sports and games. Athletics is important for all children. It teaches how to win, how to lose, perseverance. It builds social skills. It creates a community. Special Olympics is all that and much more. To cut it is but a drop in the bucket of the budget but sends a clear message. A losing message.  See the CNN report here.


Elsevier "Withdraws" Spanish Sheep Veterinary Study: By Celeste McGovern

Elsevier
"Non Solus" except "Scholar" has been replaced by "Pharma."

Thank you Celeste McGovern for allowing us to excerpt and link her article. I took Latin in high school, and am always interested in mottoes. Non Solus as the motto for publisher Elsevier described the symbiotic relationship between publisher and scholar. Alas, scholar has been replaced by pharma.

###

Elsevier’s “withdrawal” of a small veterinary study breaks all the rules of scientific publishing. The biggest name in scientific literature has produced fake medical journals for Merck’s advertisers before, so yanking a study that doesn’t pass the vaccine industry’s sniff test would be nothing. Celeste McGovern looks at a case study of how Pharma is killing science.

It’s not often that veterinary research is so controversial that it falls into the jaws of censorship zealots. That is exactly what happened recently, however, when editors at a science journal suddenly turned on a small Spanish sheep study which they had already peer-reviewed and published and stamped it: “WITHDRAWN” — the equivalent of a scarlet letter “A” in the science publishing world.  This was not about shoddy science or ethical breaches; an editor tried to soothe the outraged veterinary professor at the head of the research. But the focus was “delicate” and “controversial” and someone — some anonymous letter-writer – had wanted the study removed, and the journal acquiesced.

Dear Dr. Luján,

“I wanted to step in here to say that your manuscript is not being retracted – which implies wrongdoing and could damage your professional reputation,” Anne-Marie Pordon, publisher of Pharmacology and Pharmaceutical Sciences titles for Elsevier journals interjected in a heated e-mail exchange between the lead researcher and various editors.  “We are withdrawing the paper, which does not imply misconduct in any way. There will be simply a statement that says “This paper has been withdrawn at the request of the _____” (Authors or Editors in the blank.)”   Pick your poison. You remove it, or we remove it.

Mercky past

Elsevier journals are described as “one of the world’s major providers of science, technical and medical information.”  They also have a skeleton or two in the closet. A decade ago, they were exposed in a private injury case for being paid by Merck to manufacture and distribute two completely fake journals to market Merck’s drugs. They looked like authentic, peer-reviewed science journals, but they contained only favourable studies about the use of Merck’s deadly Vioxx and another drug with potentially fatal side effects. Nowhere did they disclose that they were paid advertising for Merck.  Four more fake Elsevier journals were sponsored by unnamed pharmaceutical companies.

Continue reading "Elsevier "Withdraws" Spanish Sheep Veterinary Study: By Celeste McGovern" »


Are There “Sleeper” VACCINE-caused Mutations Cytochrome P450 Genes Produce Which Medicine Deliberately Ignores?

Science post imageRead the full article by Catherine Frompovitch at NaturalBlaze

Abstract

The human cytochrome P450 (CYP) superfamily comprises 57 genes. These genes code for enzymes that can have a role in: metabolism of drugs, foreign chemicals, arachidonic acid and eicosanoids; cholesterol metabolism and bile-acid biosynthesis; steroid synthesis and metabolism; vitamin D(3) synthesis and metabolism; retinoic acid hydroxylation; and those of still unknown function. Cytochrome P450 was once believed to be mainly a hepatic drug detoxication system, but is now understood to include a myriad of enzymic reactions implicated in important life processes. Mutations in many CYP genes cause inborn errors of metabolism and contribute to many clinically relevant diseases. [2]

Question: Are metabolism differences in CYP genes the cause of many vaccine adverse reactions, especially brain encephalopathy that precipitates Autism and other clinically relevant diseases in infants, toddlers and even adults? Was that the reasoning why a Vaccine Court Master awarded Hannah Poling’s Autism claim $1.5 million plus ongoing $500,000 per year for life [4]?


James Lyons-Weiler on the New MMR/Autism Study From Denmark

James Lyons WeilerAoA links to Lyons-Weiler's review of the new paper by Hviid:"

An Autopsy on Hviid et al. 2019’s MMR/Vaccine Science-Like Activities

JUST IN TIME to be sandwiched between two one-sided Senate Hearings, a new cohort study by Hviid et al. has all of the hallmarks of a completely well-done study.  Well done as in overcooked.  Here is my initial assessment.

The burnt ends on this brisket are obvious.  Just like all the past studies on the MMR/autism question, the study focuses on one vaccine.  This is a problem because the variable they call “genetic risk” (having an older sibling), which is the most significant variable, is confounded with health user bias (there is no control over vaccine cessation).  It’s an important variable, but genetic risk of what?  Of autism?  Or of autism following vaccination?  It’s impossible to tell because the study never tests a VACCINE x FAMILY HISTORY interaction term.  Or any other interaction term that includes vaccines.

Were it not such an imporant question for which so much “science-like activities” have occurred, we could just shrug our shoulders, one could argue that defining the data analysis strategy is just about how one like to season their meat.  But there is real evidence Hviid (who did the data analysis) appears to be up real data cookery here.

(1) The smoking gun is the study-wide autism rate of 0.9-1%.  The rate of ASD in Denmark is 1.65%.  Where are the missing cases of ASD?  Given past allegations of this group’s malfeasance and fraud, the rest of the study cannot be accepted based on this disparity alone: the study group is not representative of the population being studied.....(continue reading at JamesLyonsWeiler.com)


Chief Medical Officer to the British Government Defends MMR Safety: Autism Up by 15 Times And Still No Explanation

image from upload.wikimedia.orgby John Stone

Since November I have been writing, on and and off about my correspondence with Dame Sally Davies, the out going Chief Medical Officer of England, and to the British Government. This correspondence is now published under Freedom of Information (barring my address and telephone number). It began when I asked Dame Sally to support her comment on the BBC about MMR "It's a a safe vaccine - we know that". 

Recently, I made this list of points which I believe emerged from the exchange:

-          ASD in schools is at least 15 times the level of 25 years ago

-          1.74% of all schoolchildren in the recent Northern Ireland census (the most complete data we have at the present time) had a severe/complex level of ASD disablement (education Stage 5)

-          The overall rate is 2.9% for the province but 4.7% for Belfast

-          Epidemiologists trying to explain the rise in ASD at the beginning of the millennium were still only talking about a rate of 0.2%

-          1999 National Statistics for schools’ mental health showed a rate of 0.2% for ASD/PDD for those born between 1984 and 88 but by the 2004 survey the overall rate was 1%

-          The rate appears to have risen 5 times during the years following the introduction of MMR and 3 times since, and the majority of cases are not fringe diagnoses

-          There is still no robust or adequate evidence of a large ASD population over the age of 35 and Dame Sally was unable to cite any

-          Our schools, and their finances, are breaking down under the burden of disablement, with ASD being frequently mentioned as the major cause

-          The social cost of ASD, once almost invisible, is set to outstrip old-age in the near future and is only likely to keep rising

-          There is no robust or adequate evidence base for MMR safety: the six studies in the single review cited by Dame Sally were flawed and inadequate

-          The first of these studies was only published 14 years after the products were introduced in the UK, and Dame Sally failed to cite any pre-marketing data, so the question also arises what the evidence base was for safety before they were introduced?

-          The MHRA yellow card scheme would be incapable picking up long term neurological effects of vaccination

-          The government has no coherent or convincing explanation of these events which are set to engulf everybody

A pdf of the correspondence can be read and downloaded here.

John Stone is UK editor of Age of Autism.


Hey there Julia, do you know anything about anything?

image from i.guim.co.ukby John Stone

The Guardian has been attacking charitable donations made to Age of Autism through the Amazon. Julia Carrie Wong, the journalist, seems to think she knows something about it.

"Age of Autism, for example, styles itself as the “daily web newspaper of the autism epidemic”. The site publishes a steady stream of content emphasizing the dangers of vaccination and promoting the discredited idea that autism is caused by “excessive vaccinations”. "

Well, Julia, perhaps you ought to take note that it was not Andrew Wakefield that said vaccines cause autism, it was the US government. Following the Hannah Poling award in 2008 Julie Gerberding, at the time Director for the centers for Disease Control, told Sanjay Gupta on CNN:

"Now, we all know that vaccines can occasionally cause fevers in kids. So if a child was immunized, got a fever, had other complications from the vaccines. And if you’re predisposed with the mitochondrial disorder, it can certainly set off some damage. Some of the symptoms can be symptoms that have characteristics of autism."

On separate occasions the Health and Human Services Health Resources and Services Administration told journalists Sharyl Atkisson and David Kirby:

"The government has never compensated, nor has it ever been ordered to compensate, any case based on a determination that autism was actually caused by vaccines. We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures."

But while autism spins out of control and is now approaching unsustainable 3% of children in the UK, and the cost of autism to the community is beginning to outstrip that of old age it becomes ever more difficult to get any serious or sensible answers out of our health officials. I recently had an  exchange with the outgoing government Chief Medical Officer, Dame Sally Davis, asking her what the evidence base for MMR safety was and she could not cite anything more convincing than the new paper from the Danish State Serum Institute: a review of six weak and flawed papers the first of which was published 14 years after the MMR was added the schedule in the UK. She was unable to mention any pre-marketing studies, or studies against placebo - it was a very poor answer. The full correspondence has now been published under freedom of information.The new paper like three of the six papers in the review, shows a protective effect against autism,indicative of bias. It sets the autism rate at 1% when in the UK is near three times higher. It is hopelessly conflicted with vaccine industry and CDC attachments, just as the Guardian is.

So, Julia, what do you think your opinion is really worth?

John Stone is UK editor of Age of Autism.

 


CHD Press Release: CDC’s ACIP Considers Expanding Recommendations for HPV Vaccine to Ages 27 to 45

 

 

Children’s Health Defense Chairman, Robert F. Kennedy, Jr., calls such discussions “reckless” based on the available safety information.

Washington, DC – The CDC Advisory Committee for Immunization Practices (ACIP) will consider recommending the Human Papilloma Virus (HPV) vaccine to both women and men ages 27 to 45 in a meeting Feb. 27-28, 2019.  This recommendation would possibly expose over 80 million adults to the Gardasil 9 vaccine.

Robert F. Kennedy, Jr. sent a letter to Chairman Jose R. Romero and ACIP members on February 25th, on behalf of Children’s Health Defense (CHD), a non-profit organization devoted to children’s health. Kennedy has diligently followed the work of the committee to evaluate and recommend vaccines to the American public for over a decade and is well aware of the dangers of this vaccine given its track record with children.

Kennedy states that CHD considers an expansion of the HPV recommendations reckless based on the safety information available and outlined numerous reasons to support his concerns.

These include the fact that during Gardasil’s clinical trials an extraordinary 49.5% of the subjects receiving Gardasil reported serious medical conditions within seven months of the start of the clinical trials. Because Merck did not use a true placebo in its clinical trials, its researchers were able to dismiss the trial participants’ injuries as coincidences, employing the term “new medical conditions,” rather than classifying their injuries as “adverse events.”

HPV Vaccines have been reported to cause death and serious adverse events in the children and young adults age group at a rate higher than for any other ACIP-recommended vaccine. Since 2006, when Gardasil came on the U.S. market, people have reported over 450 deaths and over 61,000 serious medical conditions from HPV vaccines to the government’s Vaccine Adverse Event Reporting System (VAERS).[1] While these numbers reflecting reported vaccine injuries are startling, they likely only represent a fraction of injuries. A HHS-funded study established that the voluntary VAERS system captures less than 1% of vaccine injuries and deaths.

In September, CHD released an ordered stipulation from Health and Human Services (HHS) where officials admitted that they were not in compliance with statutory requirements for regular childhood vaccine safety reviews and reports to Congress, as required in the “Mandate for Safer Childhood Vaccines” section of the 1986 law: “National Vaccine Injury Compensation Act.” In early February, in a similar ruling, FDA admitted that they had no records of clinical trials relied upon to approve any currently licensed influenza or Tdap vaccine used in pregnant women.

Kennedy’s letter informs Romero that CHD will seek to hold ACIP members supporting the recommendation accountable for endangering this population with a product that has little proven efficacy but which likely puts them at higher risk of developing cancers and other grave health conditions.


US Take Action: Wed. measles hearing will be a pharma only show

Urgent call to actionFrom Autism Action Network

The US House of Representatives Oversight & Energy Subcommittee, of the Energy and Commerce Committee, will hold a hearing on the current measles outbreak and response efforts this Wednesday, February 27 at 10 am in the John D. Dingell Room 2123 of the Rayburn House Office Building. The focus of the hearing was obvious in the press release, “Measles is a highly contagious, life-threatening virus that was previously eliminated in the United States thanks to the success of the measles vaccine,” the four bipartisan Committee leaders said. “Unfortunately, measles cases are on the rise as a consequence of the virus’s transmission among unvaccinated groups.” No critics of federal vaccine policy or the vaccine industry will be allowed to speak.

Please call Rep. Frank Pallone, the Chair of the Oversight & Energy Subcommittee and let him know you do not want the federal government to endanger our right to say “no,” and to let vaccine critics speak at the hearing:

(202) 225-4671

 And call Pallone’s boss,  Speaker of the House Nancy Pelosi, who has ultimate control over what hearings are held and who is allowed to speak, with the same message:  

(202) 225-4965

 Please click on the link below to send messages to your member of the House and the two US Senators from your state letting them know that you support vaccine choice.

http://capwiz.com/a-champ/issues/alert/?alertid=80616671&queueid=11814080981

 The hearings appear to be the next phase in a script the vaccine industry has been following around the world to eliminate vaccine choice. First, predictable outbreaks of measles, which was considered little more than a childhood inconvenience a generation ago, has been rebranded as a killer disease. Outbreaks that until recently were considered insignificant are used to whip up hysteria by corporate media outlets that rely on advertising dollars from the big four drug companies, Merck, Pfizer, Sanofi and Glaxo (who also control more than 80% of the global vaccine market). Governments are frightened and bribed into eliminating vaccine choice for their populations delivering unimpeded access to captive markets. This scenario has played out in Italy, France, Croatia, Romania and California, and now appears to be slated for all of the United States.

 Please share this message with friends and family, and please post to social networks. And if you support the work of the Autism Action Network please make a donation at www.autismactionnetwork.org


Urgent Action Required to Maintain Our Medical Freedom to Choose

image from ahrp.org

From AHRP

FYI & Action
History is repeating itself! Once again, a massive propaganda machine has fomented disease hysteria, preempting rational public health policy decisions. Last time around, coercive medical sterilizations were performed in the U.S.; their goal was to “cleanse the genetic pool of undesirables”. This time around, the objective is to increase utilization of vaccines, and thereby increase ever higher profit-margins.

The pharmaceutical industry in partnership with the U.S. government is determined to increase vaccination uptake by stripping parents of their human right to exercise their parental responsibility, which is to protect their child from risks of harm.

A growing number of parents have raised doubt about the assurances given that all vaccines are “safe and effective”. Parents are raising concerns about the empirical evidence of an ever increasing number of vaccinated children who suffer from debilitating chronic illnesses as never before. The failure of public health officials to examine the evidence and identify the cause of children’s chronic ailments, focusing solely on vaccination rates, has resulted in the loss of trust...(Continue reading at AHRP)


Robert F Kennedy Jr Blocked From Giving Evidence At Congressional Hearings

Breaking newsRobert F Kennedy jr has said that he is being prevented from giving evidence at two Congressional hearings on the grounds that they are full. It is ever more essential that everyone contacts their representatives to insist that all sides should be heard, particularly if their representatives are members of those committees.

We re-publish the letter from last week giving details of the two hearings.

Maintaining Medical Freedom: Urgent Action Required!

Threats to end religious and philosophical vaccine exemptions have just been ratcheted up to an unprecedented federal level. If parents and caregivers are stripped of the ability to make healthcare decisions for their children, reinstating that ability may be nearly impossible. We need to take action now to prevent the government from dictating what is injected into our children.

On Wednesday, FDA Commissioner Dr. Scott Gottlieb hinted in a CNN interview that if non-medical vaccine exemptions were not abolished at the state level, federal health agencies may intercede. This is especially ominous considering two critical upcoming vaccine-related hearings recently announced on Capitol Hill:

We absolutely must have representation at these hearings. It’s crucial that we have as many parents and advocates as possible in attendance at both. And if your Senator or Congressional representative is on one of these committees, it is critical that they hear from you! Click here for the Energy & Commerce Oversight and Investigations Subcommittee members and here for the HELP Committee members.

Every single one of us needs to contact our Congressional representatives and Senators starting right now. In your communications, be sure to emphasize that:

  • These hearings need to be fair, balanced, and include opposing viewpoints. We have many highly qualified individuals to present those viewpoints.
  • Issues related to vaccines should be governed by the states.
  • Over $4 billion has been paid out for vaccine injuries and deaths and HHS estimates less than 1% of adverse events are reported. Mandating any procedure involving such risks is unethical.
  • HHS has failed in its Congressional directive to study vaccine safety for 30 years.
  • Mandating liability-free vaccines that have not been properly safety tested is in direct opposition to the first tenet of the Nuremberg Code: The voluntary consent of the human subject is absolutely essential.

If you have a vaccine-injured child, tell your story. This personal input to those who represent you in our nation’s capital illustrates the harsh reality of a vaccine program geared towards industry profit rather than public health.

We have much more information on all the many ways our government has failed to protect our children here and factual information that may aid in the defense of health freedom and pushing back mandates here.

The future of medical freedom is at stake. Ensuring that our federally elected representatives hear from all of us through emails, faxes and phone calls to both their DC and district offices has never been more important than it is at this moment. If we are to maintain medical freedom and protect the health of generations to come, we need to raise our united voices now! Please share this alert with friends and family and urge them to do the same.

 

 


The United States Government Told You Vaccines Cause Autism

Following the Hannah Poling award in 2008 Julie Gerberding, at the time Director for the centers for Disease Control, told Sanjay Gupta on CNN:

"Now, we all know that vaccines can occasionally cause fevers in kids. So if a child was immunized, got a fever, had other complications from the vaccines. And if you’re predisposed with the mitochondrial disorder, it can certainly set off some damage. Some of the symptoms can be symptoms that have characteristics of autism."

On separate occasions the Health and Human Services Health Resources and Services Administration told journalists Sharyl Atkisson and David Kirby:

"The government has never compensated, nor has it ever been ordered to compensate, any case based on a determination that autism was actually caused by vaccines. We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures."

The United States Government told you vaccines cause autism.

 


Is Heidi Larson Out of Her Depth?

H larsen Deep waterBy John Stone

Having raised the issue of Heidi Larson's intervention in the vaccine debate on the BBC last week, it is worth considering - given her global status as vaccine confidence chief - how much she actually knows, but also her lack of professional accountability. Indeed, the first time she came to the attention of Age of Autism was when she wrote an article in New Scientist helping to lobby the United Nations (successfully as it turned out)  not to place a ban on mercury in vaccines under the title: "Poison pill: Not all mercury is toxic". Troubling perhaps in retrospect apart from the very poor argument is that the case was not being made by a medical doctor or toxicologist, but someone who was not professionally accountable for such an opinion. We met the same problem with her recent broadcast:

Well, I think the main thing is there most incredibly extensive safety around vaccines - the processes that go around vaccines,  the reasons there is quite a while between when vaccines are developed and when children actually get them is because the system has become more and more and more robust around safety. Frankly, partly because of the public cry  for this,  but it has always been that way from a safety perspective because the government frankly is accountable and if it is recommending and requiring in some senses these vaccines in some senses it is not in the interest of the governments or the producer to be recommending something which is going to cause any damage. 

You could say this sounds like a satirical parody of someone defending vaccine safety. It is not merely that we find ourselves in disagreement over facts, it is actually that the language is vague and she does not seem to remotely know what she is talking about. Of course, it would be much easier to advocate that vaccine are safe, carefully trialed and monitored, if you really did not know anything much about it beyond your own propaganda.

Previously, Larson has pronounced herself concerned about vaccine safety. She told Johnson & Johnson website in 2017:

Yes, there are potential risks—there will always be potential risks with any medical treatment. And we don’t talk enough about that.

Which is all very well perhaps until you accuse the people who are talking about it of the equivalent of "hate crime". Adriana Gamondes reported in these columns last month:

The corporation was so uninterested in Brabant’s adverse reaction [to a yellow fever vaccine] that even Dr. Heidi Larson—lead researcher for the Gates Foundation’s Vaccine Confidence Project—called the company’s response “inadequate” and suggested that the vaccine formulation—which has not changed since the 1960’s—is not only outdated but being given in too large a dose. Interestingly, Larson holds up Sanofi-Pasteur’s conduct in this case as an example of the damage corporations do to public confidence in vaccination.

But is it going too far to suggest that Brabant's injuries seem real to Larson because she and he had both worked for UNICEF: they are part of the same class - the rest of us can apparently go hang. And you become credible because you move in the right circles:

Continue reading "Is Heidi Larson Out of Her Depth?" »


Heidi Larson Calls For Vaccine Criticism To Be Prosecuted As Hate Crime

 

ReallyBy John Stone

Heidi Larson, the director of Vaccine Confidence Project, was seen and heard on the BBC's Victoria Derbyshire Show on Friday morning. Here is an extract:

HL: Well, I think the main thing is there most incredibly extensive safety around vaccines - the processes that go around vaccines,  the reasons there is quite a while between when vaccines are developed and when children actually get them is because the system has become more and more and more robust around safety. Frankly, partly because of the public cry  for this,  but it has always been that way from a safety perspective because the government frankly is accountaH larsenble and if it is recommending and requiring in some senses these vaccines in some senses it is not in the interest of the governments or the producer to be recommending something which is going to cause any damage. 

 VD: Should Facebook  take these private groups down?
 
HL: I think the issue with Facebook is a difficult one because on the one hand they are asked not to dig into  people's personal areas and on the other hand being asked to go and take things down so I think from a Facebook perspective its difficult to do that. From a public health perspective as we saw in the letter from Andrew Schifft (sic) to Mark Zuckerberg that this is something in the league of like hate crime....

Of course, it is hard to know where to begin. Heidi may pronounce herself satisfied with vaccine technology but frankly she is just emoting - and she has no right to take the matter out of the public's hands. To the best of my knowledge since I have been involved in these matters, the only attempts I have seen to reassure the public have been socially repressive. Obviously, we are in a situation of accelerating unpleasantness with every last measles case being hyped as if it was Ebola. But as readers will be aware when I quizzed the UK's outgoing Chief Medical Officer about the evidence basis for MMR safety she came out only with generalities and only named the very weak Luke Taylor "meta-analysis" for the safety of the products. Dame Sally could not cite pre-marketing trials against placebo (or any pre-marketing trials at all), she could only cite a paper published 26 years after the products were introduced in the U.K. 1988, while the earliest of the papers reviewed in it was published no earlier than 2002. It may be that this is what Larson had in mind: that before the public concern there had been no proper studies, and then there were the studies our governments did produce when they were in a corner - and these studies were anything but "more and more and more  robust".  As I wrote to Dame Sally:

Continue reading "Heidi Larson Calls For Vaccine Criticism To Be Prosecuted As Hate Crime" »


Dr Jayne Donegan: "Independent, Objective and Unbiased"

Unbiased
A recent interview with British general practitioner, Dr Jayne Donegan, talking about her strange story to Polly Tommey when in 2007 she was tried before a General Medical Council tribunal and completely exonerated. With thanks to Peeps TV.

 

 

A written account by her of these events can be found at her website.


Britain's Chief Doctor Exits Having Made Poor Case For MMR Safety

image from upload.wikimedia.orgby John Stone

In November we published an extract from a letter to myself from the British Government's chief medical officer, Dame Sally Davies, and the full text of her letter has now been published by the British Government under Freedom of Information. However, the timing is somewhat interesting. While the text was apparently released by her department on 21 Dec last year it was not actually published to the web till two days before she announced her retirement on 8 February. Clearly you would expect someone in her position to present the best evidence available.Here is the full text of her letter below with my original article underneath (with thank to Angus Files for pursuing this matter). I had asked Dame Sally to support her statement "It's a safe vaccine -we know that". This was her reply:

Vaccine safety is extremely important and taken seriously, and the safety of MMR vaccines has remained under continual review. As with any vaccine, MMR vaccines can have side effects in some people, and these are listed in the product literature. The potential for side effects has to be balanced against the benefits of protection against what can be very serious and potentially life threatening infections. When safety issues have been confirmed in the past these have been acted upon. Your e-mail refers to the action taken with Urabe mumps-containing vaccines, and another example includes the identification and precautions around the risk of immune thrombocytopenic purpura with MMR vaccines. Should emerging evidence confirm any new risks, I can assure you that appropriate action would be taken.

Specifically in relation to whether MMR vaccines may be a cause of autism, a substantial body of population-based research has found no evidence to suggest a causal association. This ev-idence (not just for MMR, but other types of vaccine) is available for review in the published medical literature, and was summarised in a meta-analysis in 2014 which is free to download (https://www.sciencedirect.com/science/article/pii/S0264410X14006367?via%3Dihub).

In relation to vaccine safety monitoring more generally, I can assure you that systems are in place to keep safety under review. This includes continual review of suspected adverse reac-tion reports (such as those submitted through the Yellow Card Scheme), evaluation of GP and hospital-based health records linked to immunisations, review of worldwide data and close collaboration with international health authorities. 

We know that confidence in the UK vaccine programme is at very high levels and the vast ma-jority of parents choose to have their children protected by vaccination. Vaccines are one of the best public health interventions we have - saving lives and preventing millions of people from getting life-threatening diseases.

 

image from religion.ua.edu

 

The Junk Safety Science Which Underpins UK Government MMR Vaccine Policy

By John Stone

I recently wrote to Dame Sally Davies, Chief Medical Officer of England and to the British government, asking her for the basis of her statement to the BBC regarding MMR: "It's a safe vaccination - we know that", and was a lucky enough to receive a reply (letter of 12 November, from which I extract):

Continue reading "Britain's Chief Doctor Exits Having Made Poor Case For MMR Safety" »


Systemic Toxicity of Aluminium Adjuvants: Prof. Christopher Exley



https://www.youtube.com/watch?time_continue=49&v=GSgk5m3tds0

Prof. Christopher Exley from Keele University in the UK presents his research on aluminium adjuvants used in human vaccinations at the BSEM and MELISA: Systemic Effects of Metal Exposure in Clinical Practice: Protecting Patients and Optimising Outcomes, Congress. The British Society for Ecological Medicine (BSEM) and MELISA Diagnostics are acknowledged for the delivery and organisation of this Congress: https://www.bsem.org.uk/ http://www.melisa.org/

For more information on the research group of Prof. Christopher Exley, please see our website at the following address: https://www.keele.ac.uk/aluminium/ (Presented in London, UK, 2018).


No US Childhood Vaccines Were Placebo Tested: Why the Pharma/Government Complex Is Getting Desperate To Shut Down The Web

  1. image from i.ytimg.comBy John Stone

A special tribute to Del Bigtree (pictured) and his team at ICAN for his stunning 88 page letter to the HHS regarding vaccine safety. As Del reported - in the latest edition of Highwire - the letter, in response to an earlier reply from the then acting Director National Vaccine Program Office, Melinda Wharton, took virtually a year to compile, and is a meticulous piece of research. Most sensationally they researched the HHS claim through US government archives that at least some pediatric vaccines had been trialed against genuine placebo, and came to a negative conclusion. Not only that, they established that none of the vaccines those vaccines had been trialed against had ever been trialed against genuine placebo either. At the end of the line the toxic products were only being compared with other toxic products, rather than against saline.

Leave aside the sceptics, for any believer in the vaccine program as a necessary intervention in public health, this should be a devastating finding. Fundamentally, the research into the safety of any of the products before marketing was simply not there. The manufacturers apparently had no faith that their proto-products could withstand this scrutiny, and for the rest they just did not care: under the alleged imperative of protecting the population it seems anything went. So even before all the sham monitoring procedures and reviews which Del and his team dismantle in forensic detail we are left with the proposition that none of the present products being given to US children – and frequently  other children across most of the developed world – have any meaningful pre-marketing safety data all. If you are believer in the program you have been let down: if you wanted a program with any pretensions to safety - supposing such a thing to be possible - it looks like you would have to start from scratch. The manufacturers did this: the governments, the politicians and the regulators (internationally) let it happen.

This damning document is published simultaneously with a demand in the UK  from the Royal Society for Public Health (which I had never heard of) to shut down comment about vaccines on the web. It echoes calls from Seth Berkley of GAVI, Heidi Larson of the Vaccine Confidence Project and the European Parliament. The pamphlet airily dismisses concerns that vaccines have side effects or that you could possibly have too many. It is pure public relations, and if the RSPH claims to be "independent" it also admits that the publication was paid for by Merck, a detail which was reported by British Medical Journal and the Guardian, but not true to form by the BBC. We have, in truth, been building to this moment for two decades: as the evidence piles up that every single aspect of the program lacks integrity or is simply rotten to the core all the perpetrators can do is call for the silencing of their critics, and maintain the products are safe because they say so. 

Watch Del introduce the letter on Highwire January 24, 2019:

 

Please help give the ICAN letter the widest possible distribution, particularly to politicians.

The full correspondence can be found here.

John Stone is UK Editor for Age of Autism.


John Stone Comments On NYT Article Written to Make Vaccine Choice Advocates A Dangerous Enemy

image from miro.medium.comNote: Our John Stone works tirelessly in the UK to dissect the vaccine safety narrative. Congratulations and thank you to him for this letter published on the NY Times site.  Check out the clever headline, "How to inoculated against anti-vaxxer yadda yadda." This presents those of us in the vaccination choice community as dangerous, like a disease. WHO recently named "us" a top ten public health thread. Move over Dengue and HIV, "vaccine hesitancy" just beat you in line.  Jokes aside, can you imagine that vaccine choice is deemed more of a public health threat than HIV?

The Times switched off comment at around 3 pm Eastern Time before comments got out of hand.

How to Innoculate Against Anti-Vaxxers

The no-vaccine crowd has persuaded a lot of people. But public health can prevail.

By The Editorial Board

"The World Health Organization has ranked vaccine hesitancy — the growing resistance to widely available lifesaving vaccines — as one of the top 10 health threats in the world for 2019. That news will not come as a surprise in New York City, where the worst measles outbreak in decades is now underway. Nor in California or Minnesota, where similar outbreaks unfolded in 2014 and 2017, respectively. Nor in Texas, where some 60,000 children remain wholly unvaccinated thanks in part to an aggressive anti-vaccine lobby..."

John Stone's letter:

"This article is an ideological folly, and it is also deceptive - it is deceptive because vaccine critics are already and have always been completely outgunned in the mainstream media. If the NYT are paranoid enough to claim otherwise there is surely something else going on. 

"Secondly, what is currently at issue is both freedom of choice and freedom of speech, and this is a dangerous combination. It is coming that we may not either criticize these liability free products or the lobby that produces them. Nor may we refuse the products. And this is entirely unreasonable - they are being placed on a pedestal, yet there are hundreds of things that can go wrong both singly and in combination (with the certainty that all or anything will be denied in advance as in this editorial). Furthermore, the industry has hundreds of more products in the pipeline, which in turn can and will be mandated for our children. The industry needs this debate kicked into oblivion because it cannot stand scrutiny.

"There is nothing in the history of either medicine or the pharmaceutical industry which suggests that this is a safe or wise way to proceed, not is it as if all doctors or medical scientists are in agreement about it.

Continue reading "John Stone Comments On NYT Article Written to Make Vaccine Choice Advocates A Dangerous Enemy" »


Meryl Nass MD comments on the New York Times editorial

image from miro.medium.comThe New York Times has just come out with an editorial and a backgrounder that favor the elimination of vaccine exemptions.  The means by which vaccines are coerced is via denying a public (and in some states a private) education to children who have not received every state-designated immunization.  The myth justifying this tyrannical penalty is that unvaccinated children pose a considerable risk of infection to their schoolmates and friends.

Yet vaccines are the only category of products in the United States for which manufacturers are faced with absolutely no liability when they cause injuries, cause deaths, or fail to generate immune responses.

While the New York Times has correctly gone after the Sackler family, who own Purdue Pharma, a small pharmaceutical company, for misleading marketing of Oxycontin and ushering in the opioid epidemic, the Times has shut its eyes to the epidemic of chronic neurological illnesses in children and adolescent caused by vaccines that are produced by some of the most profitable corporations on earth.  (Two examples include narcolepsy in adolescents due to Pandemrix vaccine, and Postural Orthostatic Tachycardia Syndrome (POTS) in adolescents due to HPV vaccine.)

After a child suffers a vaccine injury, parents subsequently often choose to reduce their childrens' vaccinations.  By requiring children from families in which there is a pre-existing vaccine injury to be vaccinated or forgo an education, we can expect a higher rate of vaccine injuries in those who are forced to comply.

Do Vaccine Mandates Improve the Public's Health or Pharma's Health?  The Examples of Measles, Mumps and Rubella (German Measles)

The NY Times editors write that "public health can prevail." And it should.  Let's examine the true magnitude of the risk to public health we face today from 3 well known childhood viruses.

MEASLES

Measles is said to be the most severe of the common childhood viral diseases, and it is the most contagious.  Yet despite all the hoopla over measles, there have been only 3 measles deaths in the US since 2000.  According to CDC, "...Measles cases in the United States occur as a result of importations by people who were infected while in other countries and from transmission that may occur from those importations..."  Apart from cases coming in from overseas, measles does not otherwise circulate in the US.

In 2003, two Americans died from measles: a 75 year old male who was exposed to measles in Israel, and a 13 year old who had received a bone marrow transplant 3 months before his death, and was severely immunocompromised"Despite an intensive search, no additional cases were detected in the surrounding area."

The next (and last) time someone died in the US with measles was in 2015.  A middle-aged, immunosuppressed woman with pre-existing conditions died from pneumonia, and on autopsy was found to have measles. 

It is unclear whether any of these 3 deaths were due to a measles virus originating from a vaccine, but it is certainly possible. The vaccine for measles is a live, attenuated virus that can occasionally cause measles disease and/or be transmitted to immunocompromised individuals by a vaccine recipient.

On average, there are about 250 cases of measles reported annually in the US, and 0.2 deaths annually.

MUMPS

On average, there are 2,500 cases of mumps reported in the US yearly.  The mumps vaccine is less efficacious than the measles or rubella vaccine, with an estimated 86% efficacy after the recommended two doses.  Immunity wanes significantly 3-5 years following vaccination.

According to CDC, "There have been no mumps related deaths reported in the United States during recent mumps outbreaks." 

RUBELLA (German Measles)

What about rubella, a virus that can cause fetal malformations?  Rubella was declared eliminated from the US in 2004. "Since 2012, all rubella cases had evidence that they were infected when they were living or traveling outside the United States."

Fewer than 10 people are diagnosed annually in the US with rubella.

I hope I have made it clear that the risk of measles, mumps and rubella posed by unvaccinated children to both healthy Americans, and to immune-compromised Americans is very close to zero.  The same holds for other conditions for which children are vaccinated.  Here is an article detailing the evidence of risk to the immune compromised from unvaccinated children that I wrote in 2015.

Vaccinating high risk children will produce a larger public health problem than not vaccinating them

In fact, there exists no reliable evidence that unvaccinated children in the US pose a serious threat to anyone; the claim that they do is an urban legend promulgated by Big Pharma and its wholly owned subsidiary, CDC.  (Note that CDC purchases $5.0 Billion in vaccines annually for the Vaccines for Children program, by far its largest line item.  Then CDC must convince the country to consume them.)

Yet how many columns inches, how many hours of TV news programs have been devoted to scaring the American public about the dire threat of measles? Fear of measles has been the major driver of the campaigns to eliminate vaccine exemptions.  Parents of immunocompromised children have been incited to frenzy about the risks posed to their children by unvaccinated classmates.  Yet they are rarely told their immunocompromised child might actually develop measles due to vaccination, or catch it from a newly vaccinated classmate.

Who really benefits from this hue and cry?  Only vaccine manufacturers, whose market is forcibly expanded, while these same manufacturers face no liability for consequent vaccine injuries.

The greater public health risk is actually posed by vaccines--to children who are at higher than average risk of a vaccine injury.  CDC acknowledges this risk in its Vaccine Information Statement for the measles, mumps rubella vaccine, which   says, "Some people should not get this vaccine."  Included in the list of who should not receive the vaccine are those with allergies to vaccine components or to a prior dose; those possibly pregnant; the immunocompromised; those with immune system problems; or those who have a close relative with immune system problems; and other conditions.

Yet some children with these conditions will surely be required to be vaccinated if exemptions are removed. In the 30 years' duration of the Department of Health and Human Services' Vaccine Adverse Event Reporting System, 89,000 adverse reactions and 445 deaths in total have been reported for measles vaccines.  These numbers dwarf the tiny number of infections that might be related to unvaccinated children.  Remember, no deaths--zero--from measles, mumps or rubella have been attributed to infections carried by unvaccinated children during the past 20 years in the USVery few infections have been imputed to them, either.

There is no scientific or public health reason to force children who are perceived by their parents to be at high risk of a reaction to be vaccinated, when the facts show that the threat they pose to the rest of us is marginal to none.  How could the NewSpeak Times get this so wrong?


Institutional Confirmation Bias and the United Kingdom Department of Health: Letter to Dame Sally Davies

image from pbs.twimg.comBy John Stone

Below is the text of my recent letter to Dame Sally Davies (pictured), Chief Medical Officer since 2010 to the British government. Davies has now replied twice to my original challenge to substantiate her comment on the BBC regarding the MMR: ""It's a safe vaccination - we know that". My original reply was published last November. It is evident that if she had a strong reply to make she ought to have made it the first time around, and the second reply was only an amplification of the first, to which I have in turn responded in more comprehensive detail. I believe it demonstrates how a government department had come to justify its choices made originally on weak evidence, and how as the decades went by the resulting decisions got worse and more desperate: and as the problems got more drastic the denial - even if believed - got more implausible.

It is interesting and likely significant that when I asked about MMR safety it was Davies who brought up the issue of autism (which I had not mentioned). This mirrors the situation two decades ago when I tried to raise the subject with the department of the rising autism numbers and they brought up Andrew Wakefield (though I had mentioned neither Wakefield or vaccines). The message is that they make the connection as a reflex, the safety of MMR and the claimed stability of the autism figures are inextricably entwined and in both instances the department are making a “leap of faith”.

My title refers to “the Department of Health", but to clarify at the beginning of this period when the original decisions were being made it was part of the Department of Health and Social Security (DHSS), and since January last year it has been called the Department of Health and Social Care (DHSC), but for the three decades during which most of this happened it was the DoH or DH.

Dear Dame Sally,

Re: MMR Safety and Autism Numbers

Thank you for your further courteous reply (20 December), however I must point to a host of anomalies (apologies for the length and detail of my reply). The MMR programme was introduced to the UK in 1988 but the earliest of the autism safety studies included in the Cochrane review 2005 [1] was published only 11 years after this (and apparently based on illegally obtained children’s records, which cannot be cross checked [2]), while the first listed in the review by Luke Taylor (2014), which you cited, comes from 14 years after the introduction of the products [3]. Indeed, in 1988 the DH recklessly favoured SKB’s Pluserix MMR vaccine although it was already withdrawn in Canada [4] and contrary to your first letter it never made an attempt to withdraw the product until the decision was made to do so unilaterally by the manufacturers in 1992 [5].

The safety of the products had not been established at the time of introduction (quite the reverse as the main one in use was known to be hazardous), and the featured studies only began when, following the intervention of Andrew Wakefield, health officials came under pressure to justify the policy. The picture became further complicated in 1999 when the problem of mercury in other vaccine products, previously unacknowledged, came to light in the US. The problem of the Cochrane paper of 2005 is that the bland reassurance it gave regarding MMR and autism is in stark contrast to the cool to scathing comments about the six autism related studies it reviewed (three of which overlap with the Luke Taylor review of 2014 which you previously gave as your evidence for MMR safety and MMR not causing autism) [6]. The manifest contradiction in the review should in itself raise red flags.

Continue reading "Institutional Confirmation Bias and the United Kingdom Department of Health: Letter to Dame Sally Davies" »


Vaccingate: Two Articles from Il Tempo

Corvelva vaccingateBelow are two articles translated into English from Il Tempo regarding vaccine purity and reliability in manufacturing.  Please refer to our article last week CORVELVA VACCINEGATE: GSK's Infanrix Hexa Exposed.

It is an interesting development that Dr Bolgan, a graduate of Harvard Medical School has associated herself with project. Meanwhile, Drs Montanari and Gatti make the important point that without hands-on, independent regulation - which is patently absent - there is no basis for trust in the products. It would be problematic enough if they were what was said on the packet, but if they are they are not the we are into another territory altogether.

About Corvelva: The CORVELVA association - Veneto Regional Coordination for the Freedom of Vaccinations - was founded in 1993 and its principle is the free choice of vaccinations. In recent years Corvelva has actively managed the vaccination objection regarding the scholastic aspect, the Juvenile Court and sanctions obtaining excellent results. These three areas, thanks to constant and continuous work, have been overcome by reaching the regional law that determines the suspension of the compulsory vaccination for all those born from 1 January 2008. Since then the Association's activity has focused on assisting those who have been injured due to mandatory and non-mandatory vaccines and on research related to the issue of vaccine damage. Today, there is a new battle for the right of therapeutic choice. We continue our work of supporting families in every aspect of freedom of choice and care.

From IlTempo.it:
The pharmacologist versus Aifa: "The vaccine investigation is correct". The validated methods required for a certifying body that deals with the release of batches

by Loretta Bolgan (pharmacologist and vaccine expert)
 
"I have to underline one important thing once and for all: Corvelva is not doing a batch release check and has not required the use of validated methods for batch analysis, as manufacturers, accredited laboratories and the ISS have to do. What you are conducting is a simple investigation that is done in the initial phase of the development of a vaccine, ie screening". Loretta Bolgan, pharmacologist expert in vaccines responds to Aifa, the Medicines Agency that, after the shocking revelations of IL Tempo on vaccines (where there is no rubella antigen in the product which should eradicate it, and there are human DNA and herbicides in the other) [READ THE ARTICLE] claimed that the "incriminated" lots were all in place after testing them [READ THE ARTICLE]. 
 
Dr. Bolgan, a graduate in Chemistry and Pharmaceutical Technology, reports to the Medicines Agency, which - after reporting the two lots indicted on the market - has replied that it has tested them. Bolgan obtained a PhD in Pharmaceutical Sciences, is currently scientific consultant lg 210, ONB and Corvelva for the analysis of vaccines. She was also a consultant in the last parliamentary committee of inquiry on the military.

Continue reading "Vaccingate: Two Articles from Il Tempo" »


Three New Papers from Vinu Arumugham

Science post imageBelow are the three recent papers from independent vaccine safety and autism researcher Vinu Arumugham et al. You can see more at ResearchGate.net.

Autism pathogenesis: Piecing it all together, from end to beginning …

Vinu ArumughamMaxim V Trushin

Increased extra-axial cerebrospinal fluid (EA-CSF) have been observed in imaging studies of infant brains, who go on to develop autism. Folate deficiency can cause defects in neural development that can affect CSF production and drainage. Folate receptor alpha antibodies (FRAA) are observed in 75% of autism patients. Maternal FRAA have also been observed in the case of neural tube defects.

Folate deficiency can cause aluminum accumulation in the brain. Autistic brains have been shown to accumulate aluminum. FRAA in the child or mother can therefore explain all the observations.

Further, autism patients have a higher genetic risk for cancer but have lower cancer rates. Many cancer cells express folate receptor alpha to transport folate required for rapid growth. Once again FRAA in autism can thus explain lower rates of cancer occurrence as FRAA block FRA expressed on cancer cells, affecting folate transport.

A majority of FRAA are of the IgG4 subclass and bind with higher affinity to the bovine folate receptor than the human folate receptor. The human and bovine FR have 90% protein sequence homology.

From allergies and parasite infections we know that IgG4 is the second stage of the immune response. The first stage is IgE against FRA. The US Institute of Medicine concluded that antigens in vaccines do cause IgE mediated sensitization. Many vaccines contain cow’s milk proteins, one of which is the bovine folate receptor protein. Bovine casein and casamino acids used as growth media for vaccine manufacture are derived from cow’s milk.

The solution for vaccine-induced IgE against FRA, is to immediately remove all non-target proteins from all vaccines by using processes such as affinity chromatography.

Correlation of type 1 diabetes trends in European countries to the number of bovine insulin and GAD65 contaminated chick embryo cell culture containing vaccines in the schedule, as predicted by the autoimmunity mechanism involving immunization with homologous xenogeneic antigens and EPIT as a potential treatment

Arumugham, Vinu

Type 1 diabetes (T1D) affects millions and is a growing problem worldwide. The etiology of T1D is considered to be unknown.
Many vaccines are manufactured using bovine milk derived proteins such as bovine casein and casamino acids as growth media to grow bacteria. These vaccines contain trace quantities of all bovine milk proteins.

Continue reading "Three New Papers from Vinu Arumugham" »


CORVELVA VACCINEGATE: GSK's Infanrix Hexa Exposed

Corvelva vaccingateThe latest press release below from Italian organization that campaigns on vaccine rights,  which has just received a grant from the Italian National Order of Biologists to the fury of GSK funded scientists from Padua University.  Now read why.


###

When we started these analysis, from the metagenomics to the chemical ones, we had a lot of questions and we were only looking for answers… After these first results, more questions have arisen and so did the concerns!

The quali-quantitative analysis of organic compound is of great importance in the pharmacological field, as potential safety problems arise from the new production processes of biological drugs and from the complex structural and biological characteristics of these products.

In Infanrix Hexa we found

  • chemical contamination from the manufacturing process or cross-contamination with other manufacturing lines;
  • chemical toxins;
  • bacterial peptide toxins;
  • insoluble and indigestible macromolecule that reacts to the protein assay, but cannot be recognized by any protein databases.

We have not found:

  • Protein antigens of diphtheria toxoids, tetanus, pertussis, hepatitis B, haemophylus influenzae B, Poliomyelitis 1-2-3;
  • Formaldehyde and glutaraldehyde, phenoxyethanol, antibiotic residues indicated in the composition;

In Infanrix Hexa there are six antigens

Tetanus, diphtheria and pertussis toxoids, D antigens of Poliomyelitis 1-2-3, hepatitis B proteins obtained with genetic engineering and Haemophylus polysaccharides chemically linked to tetanus toxoid as carrier. Toxoids are created by treatments with formaldehyde and glutaraldehyde that should remove toxicity keeping intact their ability to stimulate protective antibodies against original toxins.

Continue reading "CORVELVA VACCINEGATE: GSK's Infanrix Hexa Exposed" »


Flu data: more FAKE NEWS from the BBC and the British Government

image from upload.wikimedia.orgby John Stone

The BBC was at it again on Friday running a report hinting that 50,000 people had died from flu in the England and Wales during the the 2017-18 season based on newly published data from the Office for National Statistics:

"There were around 50,100 excess winter deaths in England and Wales in 2017-18 - the highest since the winter of 1975-76, figures from the Office for National Statistics show...The increase is thought to be down to the flu, the ineffectiveness of the flu vaccine in older people and spells of very cold weather last winter."

One fundamental problem with this is that the government had already published the influenza death toll for the season in May - it was indeed an exceptionally  bad year but it still only meant 320 deaths in England and 372 in the United Kingdom as a whole (which includes Scotland, Wales and Northern Ireland):

"Through the USISS mandatory scheme, a total of 3,454 ICU/HDU admissions of
confirmed influenza were reported across the UK from week 40 2017 to week 15 2018,
including 372 deaths, based on combined data from England, Scotland and Northern
Ireland. In England, the total number of influenza confirmed admissions to ICU/HDU
was 3,175 (rate of 0.22 per 100, 000 population) and 320 deaths during the same
period...

"The cumulative number of cases and deaths were higher compared to the 2016 to 2017
season (992 cases (rate of 0.06) and 112 deaths) and to the 2015 to 2016 season
(2,173 cases (rate of 0.14 per 100, 000) and 166 deaths) in England. This season
represents the highest number and rate observed since the beginning of the scheme
..."

Public Health England, 'Surveillance of influenza and other respiratory viruses in the UK:Winter 2017 to 2018' p. 21

It is also interesting to note that the issue of high mortality for the period came to light early on and was even reported in some national newspapers. In the British Medical Journal Hiam and Dorling wrote in March:

"Within the first seven weeks of 2018, some 93 990 people died in England and Wales.1 Over the same weeks in the previous five years, an average of 83 615 people died..This rise of 12.4%, or 10 375 additional deaths, was not due to the ageing of the population. Ageing is a slow process and leads to slow, not sudden, rises in mortality...An additional person died every seven minutes during the first 49 days of 2018 compared with what had been usual in the previous five years. Why?

"Not the weather or flu

"The weather was unusually mild during the initial weeks of this year—very cold weather did not arrive until late February. The mean temperature was 4.1°C across the UK in January 2018, almost half a degree above the average for this time of year."

Continue reading "Flu data: more FAKE NEWS from the BBC and the British Government" »


More Junk Autism Data From The British Government

image from www.nhs.ukBy John Stone

In my letter to the British government's leading medical adviser, Dame Sally Davies, published in these columns two days ago I commented:

"When the DHSC last surveyed this problem in 2004-5 the overall ASD rate among school children was ~1% which was 5 times higher than the rate for those young people born between 1984-8 mostly before MMR was introduced, as reported in the equivalent 1999 survey. Since then your department has neglected to look at the issue (apart from a couple of failed adult autism surveys) as everything manifestly got worse, year on year."

By a strange coincidence the government published its first survey of child and adolescent mental health (including autism) in 13 years the day after my letter to Davies was dispatched, placing the overall prevalence of autism in English schools at 1.2%, completely out of line with the situation engulfing our schools. My criticisms of the new data have now been published in British Medical Journal Rapid Responses:-

Scepticism regarding the NHS survey 'Mental Health of Children and Young People, 2017' and ASD/PDD

I note the recent comment of Prof Philip Graham in Guardian letters [1] regarding the publication of these figures:

" In addition, the rate of autism spectrum disorder was stable between 2004 and 2017, providing no support for the commonly held view that rates of this disorder are rising."

I doubt even using the figures for the 2017 survey [2] against the 2004 survey [3] that Prof Graham is justified since the overall figure for 2004 is 0.9% and the figure for 2017 is 1.2% and my rudimentary maths makes this an un-negligible 33% rise, while the the level for boys was 250% higher between the 17-19 year-olds and the 5-10 year-olds (1% against 2.5%). I also note that these figures are discrepant from the 2004 survey. For instance the 2017 survey measures the level of autism for boys in the 17 to 19 group at 1% when it was 1.9% 5-10 years in 2004, and this suggests inconsistency. In fact, the survey admits [4]:

"ASD was not associated with age. Rates appeared higher in younger age groups than
older ones (1.5% of 5 to 10 year olds; 1.2% of 11 to 16 year olds; 0.5% of 17 to 19
year olds). However, due to the small number of cases identified in the sample, the
survey was underpowered to detect variation."

Continue reading "More Junk Autism Data From The British Government" »


The Junk Safety Science Which Underpins UK Government MMR Vaccine Policy

image from religion.ua.eduBy John Stone

I recently wrote to Dame Sally Davies, Chief Medical Officer of England and to the British government, asking her for the basis of her statement to the BBC regarding MMR: "It's a safe vaccination - we know that", and was a lucky enough to receive a reply (letter of 12 November, from which I extract):

Specifically in relation to whether MMR vaccines may be a cause of autism, a substantial body of population-based research has found no evidence to suggest a causal association. This evidence (not just for MMR, but other types of vaccine) is available for review in the published medical literature, and was summarised in a meta-analysis in 2014 which is free to download (https://www.sciencedirect.com/science/article/pii/S0264410X14006367?via%3Dihub).

In relation to vaccine safety monitoring more generally, I can assure you that systems are in place to keep safety under review. This includes continual review of suspected adverse reaction reports (such as those submitted through the Yellow Card Scheme), evaluation of GP and hospital-based health records linked to immunisations, review of worldwide data and close collaboration with international health authorities.

It is noteworthy that the "meta-analysis" by Luke E Taylor is identical to the one cited by Thomas Insel to a US Congressional committee in 2014, but it constitutes no more than a bureaucratic fig-leaf. Dame Sally - who is the UK's leading government adviser on medical matters - ought to be able to do a lot better than this if every child is to be subjected to these products. It is, if anything, a rather naive response citing a shallow collection of studies which were published under political pressure decades after the policy was introduced. I have since attempted a conscientious and detailed reply:

 

21 November 2018

Dear Dame Sally,

Thank you for your letter of 12 November. I would point out that though you are quite right I am concerned about the rise in autism I specifically asked about the evidence base for MMR safety. That said it is reasonable to point out autism for a whole host of reasons is a much more serious problem in modern Britain (and elsewhere) than measles. When the DHSC last surveyed this problem in 2004-5 the overall ASD rate among school children was ~1% which was 5 times higher than the rate for those young people born between 1984-8 mostly before MMR was introduced, as reported in the equivalent 1999 survey. Since then your department has neglected to look at the issue (apart from a couple of failed adult autism surveys) as everything manifestly got worse, year on year [1,2].

As it is, a recent survey carried out by the Department of Health in Northern Ireland showed that the rate had risen from 1.2% in 2009 to 2.9%, while in Belfast it was as high as 4.7%. Moreover, 60% are educational Stage 5 [3], ie the most severe level of disability, so these are not cases that could previously have been missed because somehow subliminal. Educational data from across the nation and reports of collapse in educational services in the media testify that Northern Ireland is not an isolated case, but just better documented [4].

Regarding the meta-review by Taylor 'Vaccines are not associated with autism' [5] which you cited I note that there are just six MMR related studies included all of which have major problems. Three of the studies show apparent protective effect of MMR vaccines against autism (Madsen 8% [6], Smeeth 14% or 22% [7] and Mrozek-Budzyn 83%!!! [8]) which suggests bias. Of the Madsen paper Cochrane 2005 warned [9]:

"The follow up of diagnostic records ends one year (31 Dec 1999) after the last day of admission to the cohort. Because of the length of time from birth to diagnosis, it becomes increasingly unlikely that those born later in the cohort could have a diagnosis"

It remains troubling that as with a number of studies from this Danish group the co-ordinator on behalf of US Centers for Diseases Control, Poul Thorsen, is wanted for financial fraud from the CDC, though not extradited to the US now after nearly 8 years [10].

Of the De Stefano paper Cochrane commented [9]:

“The conclusion, however, implied bias in the enrollment of cases which may not be representative of the rest of the autistic population of the city of Atlanta, USA where the study was set.”

And indeed in 2014 the paper was repudiated by one of the leading authors, William Thompson [11]:

“I regret that my coauthors and I omitted statistically significant information in our 2004 article published in the journal Pediatrics. The omitted data suggested that African American males who received the MMR vaccine before age 36 months were at increased risk for autism. Decisions were made regarding which findings to report after the data were collected, and I believe that the final study protocol was not followed.”

The study by Smeeth [7] is compromised by its patchy data source, the General Practice Research Database where the autism rate represented is perhaps only one tenth of cases diagnosed [12]. Cochrane commented [9]:

“In the GPRD - based studies (Black 2003; Smeeth 2004) the precise nature of controlled unexposed to MMR and their generalisability was impossible to determine…”

It remains problematic whether the unvaccinated in this study were genuinely unvaccinated.

Of the Uchiyama study [13] Cochrane commented [14]:

“The cohort study of Uchiyama 2007 was potentially affected by a different type of bias, considering that the participants were from a private clinic and that definitions of applied Autistic Spectrum Disorders (ASD) diagnosis and of methods used for ASD regression ascertainment were not clearly reported.”

And the Uno study [15] will suffer from similar issues since the cases came from the same clinic. Moreover, in both instances the studies were far too small (904 persons and 413) to necessarily provide any clear result even if they had been better controlled.

Nor can the Taylor meta-analysis [5] cover up the entire absence of pre-marketing studies. In 1988-9 when the British government was persuaded to introduce Pluserix, MMR2 and Imravax there were no safety studies at all, and successive governments have been forced into the defence of a policy which they had embarked on without safety evidence.

As to the robustness of the yellow card reporting system I note the recent correspondence in the columns of BMJ On-Line regarding monitoring of Pandemrix vaccine from Wendy E Stephen and Clifford G Miller [16], which has serious implications for how the MHRA monitor all products. The MHRA has, of course, the ultimate conflict of being entirely funded by the manufacturers. It may be mentioned that in 1992 the Pluserix and Imravax vaccines were withdrawn not apparently by the British Government concerned about patient safety but by the manufacturers catching the government on the hop [17].

We are confronting a catastrophic situation among our young people with chronic illness replacing infectious illness as the main issue and cost to the state, and laying the emphasis on infectious diseases (with endless hate campaigns in the media against critics labelled “anti-vaxxers”) is a distraction, and a distortion of policy. It would be unfortunate if ministers were being advised about the safety of the programme on such a threadbare and inadequate basis. Re-examining the policy is both essential and urgent.

[1] John Stone,  ‘Response to David Oliver I (The Indisputable Rise in Autism)’, BMJ Rapid Responses 28 August 2018, https://www.bmj.com/content/362/bmj.k3596/rr-12

[2] John Stone, ‘What about autism?’ BMJ Rapid Responses, 21 August 2018, https://www.bmj.com/content/362/bmj.k3596/rr-0

[3] Information Analysis Directorate 'The Prevalence of Autism (including Asperger Syndrome) in School Age Children in Northern Ireland 2018', published 10 May 2018, https://www.health-ni.gov.uk/sites/default/files/publications/health/asd-children-ni-2018.pdf

[4] Responses to Viner RM, 'NHS must prioritise health of children and young people', https://www.bmj.com/content/360/bmj.k1116/rapid-responses

[5] Luke E Taylor et al, ‘Vaccines are not associated with autism: An evidence-based meta-analysis of case-control and cohort studies’, Vaccine 2014, https://autismoevaccini.files.wordpress.com/2014/05/vaccines-are-not-associated-with-autism.pdf

[6] Madsen et al, ‘A Population-Based Study of Measles, Mumps, and Rubella Vaccination and Autism’, NEMJ 2002, https://www.nejm.org/doi/full/10.1056/NEJMoa021134

[7] Smeeth et al, ‘MMR vaccination and pervasive developmental disorders: a case-control study.’ Lance 2004, https://www.ncbi.nlm.nih.gov/pubmed/15364187

[8] Mrozek-Budzyn et al, ‘Lack of association between measles-mumps-rubella vaccination and autism in children: a case-control study.’ Pediatric Infectious Diseases Journal 2010, https://www.ncbi.nlm.nih.gov/pubmed/19952979

[9] Demicheli et al, ‘Vaccines for measles, mumps and rubella in children.’, Cochrane Database Syst Rev. 2005 Oct 19;(4):CD004407.

[10]  Office of Inspector General, US Department of Health and Human Services, Fugitive Profiles, https://oig.hhs.gov/fraud/fugitives/profiles.asp

[11] https://legislature.vermont.gov/assets/Documents/2016/WorkGroups/House%20Health%20Care/Bills/H.98/Witness%20Testimony/H.98~Jennifer%20Stella~William%20Thompson%20Statement~5-6-2015.pdf

[12] John Stone, ‘An old story: the GPRD does not provide credible autism data’ 11 February 2014 https://bmjopen.bmj.com/content/3/10/e003219.responses

[13] Uchiyama et al, ‘MMR-vaccine and regression in autism spectrum disorders: negative results presented from Japan.’ J Autism Dev Disord. 2007 Feb;37(2):210-7.

[14] Demicheli et al, ‘Vaccines for measles, mumps and rubella in children.’, Cochrane Systematic Review - Intervention Version published: 15 February 2012, https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004407.pub3/full

[15] Uno et al, ‘The combined measles, mumps, and rubella vaccines and the total number of vaccines are not associated with development of autism spectrum disorder: the first case-control study in Asia’, Vaccine. 2012 Jun 13;30(28):4292-8. doi: 10.1016/j.vaccine.2012.01.093. Epub 2012 Apr 20.

[16] Responses to Godlee, ‘A tale of two vaccines’ BMJ 2018, https://www.bmj.com/content/363/bmj.k4152/rapid-responses

[17] Report, BMJ 26 September 1992, https://www.bmj.com/content/305/6856/777

When your government, the BBC or the mainstream media tell you that MMR is safe,  this the best that the British government can do. After three decades of pure bluster they need to go back to the drawing board.

 

 


Role of NMDA receptor autoimmunity induced by food protein containing vaccines, in the etiology of autism, type 1 diabetes, neuropsychiatric and neurodegenerative disorders

NmdaNote: Despite tomorrow being America's super food consumption day.....

Vinu Arumugham. (2018, October 16). Role of NMDA receptor autoimmunity induced by food protein containing vaccines, in the etiology of autism, type 1 diabetes, neuropsychiatric and neurodegenerative disorders. Zenodo. http://doi.org/10.5281/zenodo.1463601

Role of NMDA receptor autoimmunity induced by food protein containing vaccines, in the etiology of autism, type 1 diabetes, neuropsychiatric and neurodegenerative disorders

By Vinu Arumugham

Vaccines contain numerous animal and plant proteins (soy, peanut, sesame, maize, wheat, etc.). Vaccine excipients are derived from plant or animal sources. The mechanism of animal protein induced autoimmunity was previously described. Following a report associating maternal gluten intake to type 1 diabetes in the offspring, plant proteins were investigated.

The Pandemrix vaccine induced narcolepsy due to molecular mimicry between a H1N1 nucleoprotein peptide in the vaccine and the human hypocretin receptor 2. The BLASTP match score for this peptide was used as a baseline. BLASTP showed strong sequence alignment between gliadin, a wheat protein, and the human ionotropic N-methyl-D-aspartate receptor (NMDAR).

Analyzing further, strong sequence alignment was found between soy, peanut, sesame, maize, wheat and human glutamate receptors (GR), both ionotropic and metabotropic. There are reports of boosted wheat allergy and de novo synthesis of NMDAR antibodies following immunization. Once immunized with plant derived antigens, antibody levels will be increased by dietary exposure to these antigens.

Continue reading "Role of NMDA receptor autoimmunity induced by food protein containing vaccines, in the etiology of autism, type 1 diabetes, neuropsychiatric and neurodegenerative disorders" »


The Role of Toxic Stimuli Combinations in Determining Safe Exposure Limits

Toxic hazardThank you to author Ronald Kostoff for this link.

An Editorial in the journal Toxicology Reports entitled "The role of toxic stimuli combinations in determining safe exposure limits" has been published recently.  The article asserts that lack of adequate testing of toxic stimuli for safety purposes in combinations reflective of real-world exposures results in regulatory Exposure Limits not fully protective.  While the Editorial applies to all toxic stimuli exposures, RFR is mentioned specifically at the end of Section 2.  The Editorial is Open Access, and can be accessed at https://doi.org/10.1016/j.toxrep.2018.10.010

The role of toxic stimuli combinations in determining safe exposure limits

1. Introduction

Since the dawn of the Industrial Age, and especially over the past century, many thousands of technologies and their products have been introduced to our society. There has been continual concern about the safety of these products, as reflected in their potential adverse impacts on human health. As a result, a number of regulatory agencies have been established for the purpose of ensuring these technology products are safe.

There are three main obstacles these agencies face in determining the degree to which Exposure Limits are protective:

Sufficiency of existing data for setting safe exposure limits (Has adequate research been done and reported on the toxic stimulus in question and does the research that has been conducted and reported reflect real-world exposures?)

Sufficiency of incorporating relevant existing data from the biomedical literature

Trustworthiness of existing data in the biomedical literature [1].

This editorial focuses on the issue of how well real-world exposure effects are reflected by the published literature. The other issues are addressed in part in a recent monograph on occupational exposure permissible limits [2].  Read the full editorial here.

 


Meet The Authors of HPV Vaccine on Trial in Rye, NY November 8

Hpv presentation Rye NY


You're invited to meet the authors of this important book from Skyhorse Publishing called HPV Vaccine on Trial this Thursday, in Rye New York.

A Groundbreaking Exposé to the HPV Vaccine and the Science, Safety, and Business Behind It

Cancer strikes fear in people’s hearts around globe. So the appearance of a vaccine to prevent cancer–as we are assured the human papillomavirus (HPV) vaccine will–seemed like a game-changer. Since 2006, over eighty countries have approved the vaccine, with glowing endorsements from the world’s foremost medical authorities. Bringing in over $2.5 billion in annual sales, the HPV vaccine is a pharmaceutical juggernaut. Yet scandal now engulfs it worldwide.

The HPV Vaccine on Trial is a shocking tale, chronicling the global efforts to sell and compel this alleged miracle. The book opens with the vaccine’s invention, winds through its regulatory labyrinths, details the crushing denial and dismissal of reported harms and deaths, and uncovers the enormous profits pharma and inventors have reaped. Authors Holland, Mack Rosenberg, and Iorio drill down into the clinical trial data, government approvals, advertising, and personal accounts of egregious injuries that have followed in countries as far-flung as Japan, Australia, Colombia, India, Ireland, the U.K. and Denmark. The authors have written an unprecedented exposé about this vaunted vaccine.

Written in plain language, the book is for everyone concerned – parents, patients, doctors, nurses, scientists, healthcare organizations, government officials, and schools. Ultimately, this book is not just about the HPV vaccine, but about how industry, government, and medical authorities may be putting the world’s children in harm’s way.


Harassment and silencing of vaccine and GM critics by the University of Exeter

image from ngw.nlBy John Stone

I am publishing this brief correspondence to highlight how our higher educational institutions are becoming the enemies of freedom of speech and intellectual curiosity, not to mention purveyors of falsehood. I am not suggesting that Exeter University is particularly unusual: there are lots of publications of this kind from many academic sources, arguing how to limit and close down debate while using ad hominem tactics posing as hard science. It is interesting to note how the university dealt with this matter. The vice-chancellor and CEO, Sir Steve Smith - who is an expert in the politics of globalisation - handed the matter on to the provost, Prof Janice Kay, a cognitive neuropsychologist, who does not really tell us what she thinks, but passes the buck to the politics department, the publishers and the peer reviewers. She must however know that our schools are by now drowning in unprecedented and unexplained neurological impairment. It seems that the university's coat of arms with the motto  lucem sequimur 'we follow the light' has fallen into disuse, and frankly the spirit of enlightenment is dead as GSK and the Bill and Melinda Gates Foundation take over the world.

From: John Stone .....
Sent: 24 October 2018 16:20
To: Vice Chancellor.....
Subject: Harassment and silencing of vaccine and GM critics

To Prof Sir Steve Smith, Vice-Chancellor and CEO University of Exeter

Dear Sir Steve,

I would like to express grave disquiet regarding the paper by Lyons et al and the additional publicity given to it by your university. It really will do no good to target people while not addressing their arguments - it is to say the least an open question who is indulging in "innuendo" as your publicity department put it.

A case in point would be the paper's attack on the competence and integrity of Robert F Kennedy Jnr. The article does not address any specifics of Kennedy's argument in his article while labelling him as "a conspiracy theorist". In this regard it is worth noting that by 2004 the British government, without of course admitting any error, had removed mercury from vaccines - the subject of Kennedy's article - and it was only to make a return to doing so in the highly unfortunate and still unaccounted Pandemrix episode. The safety of using the mercury salt preservative thimerosal/thiomersal has been criticised in many scientific publications.

A further problem is that if people are not allowed to express their concerns - or even their unpleasant experiences - a class of product becomes protected and the hazards to the public increase. There can be no automatic assumption that products are safe, and what is proposed is the intellectual and social suppression of views, experience and knowledge inconvenient to global interests and governments. This does not mean that all opinions are equally valid but it does mean that public debate should be tolerated. The very failure to tolerate debate places a question mark of the motives of the people trying to deny it, and it leaves the public in a dangerous position. It is always possible that this or that product has been slandered, but it does not mean that all products or all public bodies meet the standard, and we cannot proceed on this basis.

I believe by promoting "research" of this kind the University of Exeter is placing itself in an invidious historical position, and I look forward to your views.

Yours sincerely,

John Stone, UK and European Editor, AgeofAutism.com

###

On 26 Oct 2018, at 15:18,

Dear Mr Stone, (if I may?)

Continue reading "Harassment and silencing of vaccine and GM critics by the University of Exeter" »


Mystery Polio-like Paralytic Disease in Children Related to Vaccination?

TractionChairSongNote: One of the straw man arguments used against anyone who discusses vaccine injury, exemptions and refusal goes like this: "Do you want polio back?" Of course, the answer is "No." Below is an article from IPAK on the frightening outbreaks of "polio-like" paralysis in children across the nation.  No child should be injured by a vaccine, or thrust into another illness because of the vaccine's intended role within the body. If a vaccine stops one disease but causes another even more harmful disease or situation, the risk far outweighs the benefit. These are the conversations parents should be able to have with their doctors. And on social media, without being called anti-vaccine and shut down. Harm is harm. And when your child is worse off after vaccination, that can hardly be called a medical miracle.

###

Mysterious Paralysis Affecting Children: Are Vaccines to Blame?

IPAK Modern Medicine and Health News Views from the Open-Minded News and views on modern medicine, health, the future of health, public health, immunity, our environment and medical law,

Eli Kammerman - October 28, 2018

[IPAK Editor's comment: The two-hit hypothesis presented addresses a cellular, but not a molecular, mechanisms of pathophysiology involving vaccination concurrent with enterovirus infection. Whether molecular mimicry or other known molecular mechanisms of vaccine induced autoimmunity also play a role remains to be tested.]

A mysterious disease is paralyzing kids in 22 states. A three-year-old who could barely hold up his own head was featured on the news after contracting a polio-like illness that started with a runny nose and turned into something much more serious. Doctors diagnosed him with Acute Flaccid Myelitis (AFM), a disease that causes sudden arm or leg weakness, and in some cases can lead to permanent paralysis. The CDC reports that so far in 2018, there have been 72 confirmed cases of AFM among a total of 191 cases currently under investigation.

But what’s causing it? And more importantly, how can we prevent it from happening to our children?

Here’s what parents need to know: AFM Peaks During Back-to-School Periods During the past five years, surveillance data reported by the CDC shows a seasonal peak in juvenile cases of acute flaccid myelitis (AFM) in three of the years (2014, 2016, 2018), with the peak occurring in the month of September and the next higher levels of cases seen in the immediately adjacent months. Read on to learn about the relationship between these seasonal peaks and the back-to-school period.

Polio


Continue reading "Mystery Polio-like Paralytic Disease in Children Related to Vaccination?" »


UK Parliamentary Committee Jettisons Vaccines As Strategy To Combat Antimicrobial Resistance

British flagAge of Autism re-posts its submission authored by its UK editor, John Stone, to the House of Commons Health and Social Care Committee inquiry into antimicrobial resistance. The resulting committee report only mentions vaccines once,  and not as a major strategy against antimicrobial resistance. This is in contrast to a British government report of 2016 in which the lead author Jim (Lord) O'Neill saw vaccines as the major tool in combatting the problem, which had occasioned the AoA evidence to the parliamentary committee. Whatever the prospect for creating new antibiotic products the committee - perhaps in a new spirit of realism - appear to have abandoned expanding the vaccine program as a substitute.

Written evidence from John Stone (Age of Autism)

[1] Vaccines are mentioned as one strategy against antimicrobial resistance (1) and this submission seeks to caution against the idea of substituting one kind of over-medication with another (Age of Autism is an on-line newspaper concerned with the publicly unaccounted adverse effects of vaccination).

[2] In the United Kingdom, an infant already receives by 12 months on the routine schedule (2):-

DTaP, Polio, HiB, HepB+Rotavirus+13 Strain Pneumococcal+MenB (8 weeks)

DTaP, Polio, HiB, HepB+Rotavirus (12 weeks)

DTaP, Polio, HiB,HepB+13 Strain Preumococcal+MenB (16 weeks)

13 Strain Pneumococcal+MMR+HiB, MenC

[3] In 2011 Miller and Goldman reported (3):

“The infant mortality rate (IMR) is one of the most important indicators of the socio-economic well-being and public health conditions of a country. The US childhood immunization schedule specifies 26 vaccine doses for infants aged less than 1 year—the most in the world—yet 33 nations have lower IMRs. Using linear regression, the immunization schedules of these 34 nations were examined and a correlation coefficient of r = 0.70 (p < 0.0001) was found between IMRs and the number of vaccine doses routinely given to infants. Nations were also grouped into five different vaccine dose ranges: 12–14, 15–17, 18–20, 21–23, and 24–26. The mean IMRs of all nations within each group were then calculated. Linear regression analysis of unweighted mean IMRs showed a high statistically significant correlation between increasing number of vaccine doses and increasing infant mortality rates, with r = 0.992 (p = 0.0009). Using the Tukey-Kramer test, statistically significant differences in mean IMRs were found between nations giving 12–14 vaccine doses and those giving 21–23, and 24–26 doses. A closer inspection of correlations between vaccine doses, biochemical or synergistic toxicity, and IMRs is essential.”

Continue reading "UK Parliamentary Committee Jettisons Vaccines As Strategy To Combat Antimicrobial Resistance" »


British Medical Journal Finally Goes Over The Top On HPV Vaccine Safety

image from upload.wikimedia.orgby John Stone

After months of infighting and latterly outright war in the scientific community - and particularly within the Cochrane Group, formerly Collaboration - British Medical Journal have finally published  a paper questioning the safety of HPV vaccines. This represents a major step forward, because they had previously backed away from publishing a review by the same authors of European Medical Agency data, preferring in May to report the official Cochrane whitewash of the products by Aubyn et al, and only reluctantly reported the paper in July by three of the present authors in its cadet journal BMJ Evidence Based Medicine criticising their Cochrane colleagues - also now defended. All the present authors are historically associated with Cochrane but matters came to a head the weekend before last when the Group sacked one of the co-authors, a founder member board member of Cochrane - Peter  Gøtzsche -  on the basis of  vague and unsubstantiated allegations of bad behaviour, followed by the resignation of four other board members.

While the Cochrane Group is now widely considered to be a sinking ship, it has been frustrating to see weeks of politics overshadowing the incredibly serious criticisms of HPV vaccine safety made in BMJ EBM in July, and this is now somewhat rectified by the new paper which documents the painful and unsatisfactory process of extracting vaccine data from the European Medicines Agency: -

Challenges of independent assessment of potential harms of HPV vaccines

After three years of trying to access trial data for HPV vaccines, Lars Jørgensen and colleagues find current transparency policies unfit for their purpose

Lars Jørgensen, Peter Doshi, Peter Gøtzsche, Tom Jefferson 

Continue reading "British Medical Journal Finally Goes Over The Top On HPV Vaccine Safety" »


Depression and Autism: More Evidence Points to Physiological Not Psychological

Cause-of-depression-gutBy Teresa Conrick

Many people think depression is feeling bad about a situation. It can be that, but many times, it is a biological happening.  A recent study hitting the news noted this about autism:

Nearly 1 in 5 autistic young adults have history of depression: study

The study seemed to have many participants but seemed to have a bit of a slant in they asked specifically -- “ particularly in the context of bullying.

And young adults with autism who were relatively high-functioning -- meaning they did not have intellectual disabilities -- were actually at higher risk of depression than people with more severe forms of autism, British researchers found…...People with autism without intellectual disabilities "may be particularly prone to depression because of greater awareness of their difficulties," the researchers theorized……

….Not all of the increase in risk for depression was caused by genetics, Rai's group added, because people with autism still had double the odds for depression compared to a full sibling who did not have the disorder. That suggests that something other than DNA -- perhaps the stress of living with autism -- may play a role in depression risk…

"Individuals receiving a diagnosis of autism spectrum disorder later in life often report long-standing stress in relation to social isolation, bullying, exclusion, and the knowledge they are different ….Peng also believes more research is needed to tease out the experiences and stigmas that may contribute to depression in young people with autism.

Continue reading "Depression and Autism: More Evidence Points to Physiological Not Psychological" »


Aluminium and multiple sclerosis

image from i.ytimg.comby Chris Exley 

(From the Hippocratic Post)

In a recent post – A role for aluminium in multiple sclerosis, we highlighted that individuals with multiple sclerosis excrete high amounts of aluminium in their urine.

It was also demonstrated that regular drinking of a silicon-rich mineral water (Why-everyone-should-drink-silicon-rich-mineral-water) facilitated the urinary excretion of aluminium. Elevated urinary excretion of aluminium exacerbated in the short term by drinking a silicon-rich mineral water is indicative of a high body burden of aluminium (http://pubs.rsc.org/en/content/articlelanding/2013/em/c3em00374d#!divAbstract).

However, the systemic origin of excreted aluminium in multiple sclerosis remained unknown though we speculated that it might be brain tissue, reflecting known intimate associations between aluminium and myelin. The latter being the primary target biomolecule in the aetiology of multiple sclerosis. .. (continue reading at the Hippocratic Post)


Dr. Chris Exley: Aluminium in Brain Tissue in Multiple Sclerosis

AnnetteNote: I remember bumping into Annette Funicello at Disney World in 1992. MS had started to ravage her body. She had a cane that was clear and full of glitter. Annette Funicello was a famous, original Mouskateer. MS did not care....  Thank you to Dr. Exley et al for their work exposing the dangers of aluminum - in all its sources, including as a vaccine adjuvant.

MDPI and ACS Style

Mold, M.; Chmielecka, A.; Rodriguez, M.R.R.; Thom, F.; Linhart, C.; King, A.; Exley, C. Aluminium in Brain Tissue in Multiple Sclerosis. Int. J. Environ. Res. Public Health 2018, 15, 1777.


###

 

Ijerph-logo



ABSTRACT

Multiple sclerosis (MS) is a devastating and debilitating neurodegenerative disease of unknown cause. A consensus suggests the involvement of both genetic and environmental factors of which the latter may involve human exposure to aluminium. There are no data on the content and distribution of aluminium in human brain tissue in MS. The aluminium content of brain tissue from 14 donors with a diagnosis of MS was determined by transversely heated graphite furnace atomic absorption spectrometry. The location of aluminium in the brain tissue of two donors was investigated by aluminium-specific fluorescence microscopy. The aluminium content of brain tissue in MS was universally high with many tissues bearing concentrations in excess of 10 μg/g dry wt. (10 ppm) and some exceeding 50 ppm. There were no statistically significant relationships between brain lobes, donor age or donor gender. Aluminium-specific fluorescence successfully identified aluminium in brain tissue in both intracellular and extracellular locations. The association of aluminium with corpora amylacea suggests a role for aluminium in neurodegeneration in MS. View Full-Text


New Study: Aluminium in Brain Tissue in Multiple Sclerosis

image from www.rescuepost.comInt. J. Environ. Res. Public Health 201815(8), 1777; https://doi.org/10.3390/ijerph15081777 (registering DOI)

Aluminium in Brain Tissue in Multiple Sclerosis

Mold M, Chmielecka A, Rodriguez MRR, Thom F, Linhart C., King A, Exley C.

 
 

Abstract

Multiple sclerosis (MS) is a devastating and debilitating neurodegenerative disease of unknown cause. A consensus suggests the involvement of both genetic and environmental factors of which the latter may involve human exposure to aluminium. There are no data on the content and distribution of aluminium in human brain tissue in MS. The aluminium content of brain tissue from 14 donors with a diagnosis of MS was determined by transversely heated graphite furnace atomic absorption spectrometry. The location of aluminium in the brain tissue of two donors was investigated by aluminium-specific fluorescence microscopy. The aluminium content of brain tissue in MS was universally high with many tissues bearing concentrations in excess of 10 μg/g dry wt. (10 ppm) and some exceeding 50 ppm. There were no statistically significant relationships between brain lobes, donor age or donor gender. Aluminium-specific fluorescence successfully identified aluminium in brain tissue in both intracellular and extracellular locations. The association of aluminium with corpora amylacea suggests a role for aluminium in neurodegeneration in MS. View Full-Text
 

British Medical Journal Fails On “First Do No Harm” Over HPV Vaccines

image from encrypted-tbn0.gstatic.comby  John Stone

"If the contents of either of the papers became widely known it would surely have sounded the global death knell for the products and also called twelve years of government policy into question. When balancing the welfare of British children against the interests of industry and state it seems in the end the children barely weighed."

Serious ethical questions arise over the role of British Medical Journal and the promotion of Human Papillomavirus vaccines. Back in May BMJ published a news report of the Cochrane Review of HPV vaccines by former London Times journalist Nigel Hawkes “HPV vaccines are effective and safe and work best in young women, review finds”. It has come to light in the blog of Prof David Healy (author Pharmageddon and Let Them Eat Prozac ) that the BMJ knew the reasons for this confidence were at best extremely controversial, and that the journal itself had turned down an earlier paper by members of Nordic Cochrane (including leading scientists Peter Gøtzsche and Tom Jefferson) highlighting major flaws in the science surrounding the products. Healy states:

“ Some months back, the Nordic Cochrane Center, one of the centres in the Cochrane Collaboration, sent a review of studies done on the HPV vaccine to the BMJ.  Much to their surprise, BMJ turned down this article which contained all studies done on HPV and a serious attempt to flag up the limitations of the trials and accordingly the limitations of what we could confidently say.”

This paper is still unpublished but two weeks ago BMJ Evidenced Based Medicine published a second paper by the Nordic Cochrane group, Lars Jørgensen, Peter Gøtzsche and Tom Jefferson attacking the foundations of the Cochrane Review, as reported on Age of Autism last week and now available in full from Prof Healy’s site. Despite the BMJ Group publication the main journal chose not to publicise this extraordinarily newsworthy event. (It might be said that news is not what it was and this is one of the most blatant suppressions of  the news in modern medicine - the "Fake" comes in not reporting.)

While there is no doubt that the BMJ Group is commercially conflicted, not only accepting advertising from all the manufacturers – GSK, Merck and Sanofi - but also being in historic partnership with Merck, perhaps the real reasons are even more disturbing and relate BMJ’s peculiar relationship as the journal of the British Medical Association (the doctors’ trade union) with the British medical profession. If the contents of either of the papers became widely known it would surely have sounded the global death knell for the products and also called twelve years of government policy into question. When balancing the welfare of British children against the interests of industry and state it seems in the end the children barely weighed.

Last week the present writer tried to challenge a senior BMA member - Dr Peter English, Chair of its Public Health Medicines Committee - in the on-line columns of BMJ:

“As a “Public Health Physician” Peter English seems to express a breath-taking disdain for the public, while also apparently eliding any critical view of vaccines at all with being “anti-science”… I wonder what he thinks the public, particularly prospective vaccinees and their families, should be allowed to know about the recent paper by Jørgensen regarding the inadequacies in the trialing of HPV vaccines?”.

Naturally, it was not published.

 PostScript: In a 2008 letter to BMJ regarding HPV vaccine, co-signed by Prof Keith Neal, Peter English discloses:

"Competing interests: Between them the authors have given occasional lectures for, received expenses for professional conferences from, and participated in advisory boards for various pharmaceutical companies, including GlaxoSmithKline, Sanofi Pasteur MSD, and others."

 

John Stone is UK and European editor of Age of Autism

 

 


Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder

Science post imageMolecular Diagnosis & Therapy ISSN: 1177-1062 (Print) 1179-2000 (Online)

  • Shannon Rose
  • Dmitriy M. Niyazov
  • Daniel A. Rossignol
  • Michael Goldenthal
  • Stephen G. Kahler
  • Richard E. Frye

ABSTRACT: Autism spectrum disorder (ASD) affects ~ 2% of children in the United States. The etiology of ASD likely involves environmental factors triggering physiological abnormalities in genetically sensitive individuals. One of these major physiological abnormalities is mitochondrial dysfunction, which may affect a significant subset of children with ASD. Here we systematically review the literature on human studies of mitochondrial dysfunction related to ASD. Clinical aspects of mitochondrial dysfunction in ASD include unusual neurodevelopmental regression, especially if triggered by an inflammatory event, gastrointestinal symptoms, seizures, motor delays, fatigue and lethargy. Traditional biomarkers of mitochondrial disease are widely reported to be abnormal in ASD, but appear non-specific. Newer biomarkers include buccal cell enzymology, biomarkers of fatty acid metabolism, non-mitochondrial enzyme function, apoptosis markers and mitochondrial antibodies. Many genetic abnormalities are associated with mitochondrial dysfunction in ASD, including chromosomal abnormalities, mitochondrial DNA mutations and large-scale deletions, and mutations in both mitochondrial and non-mitochondrial nuclear genes. Mitochondrial dysfunction has been described in immune and buccal cells, fibroblasts, muscle and gastrointestinal tissue and the brains of individuals with ASD. Several environmental factors, including toxicants, microbiome metabolites and an oxidized microenvironment are shown to modulate mitochondrial function in ASD tissues. Investigations of treatments for mitochondrial dysfunction in ASD are promising but preliminary. The etiology of mitochondrial dysfunction and how to define it in ASD is currently unclear. However, preliminary evidence suggests that the mitochondria may be a fruitful target for treatment and prevention of ASD. Further research is needed to better understand the role of mitochondrial dysfunction in the pathophysiology of ASD.


Bad Bacteria in Mom's Gut as Autism Trigger

Open refrigeratorThe latest study being blasted around the internet has a focus on pregnant mom’s gut, or her diet, and how it could cause her child to “get autism”, as the different articles seem to imply.  

Mom’s Gut Microbiome May Impact Kids’ Autism Risk 

….An unhealthy microbiome in the mother can make her unborn offspring susceptible to neurodevelopmental disorders. The researchers found that the IL-17a molecule was a key contributor to the development of autism-like symptoms in lab mice.

The good news is that the microbiome can be easily changed, either through diet, probiotic supplements or fecal transplant. All of these approaches seek to restore a healthy equilibrium among the different microorganisms that live in the gut.

“In terms of translating our work to humans, I think the next big step would be to identify features of the microbiome in pregnant mothers that correlate with autism risk,” Lukens said. “I think the really important thing is to figure out what kind of things can be used to modulate the microbiome in the mother as effectively and safely as we can.”

Blocking IL-17a also might offer a way to prevent autism, but it carries much more risk.

“If you think about pregnancy, the body is basically accepting foreign tissue, which is a baby,” said Lukens. “As a result, maintenance of embryonic health demands a complex balance of immune regulation, so people tend to shy away from manipulating the immune system during pregnancy.”.....

But, isn’t vaccinating, manipulating the immune system?  We will discuss that more.

Now some may say, when will researchers finally stop blaming mothers for autism?  Since the days of Refrigerator Mothers,  mothers have had blame thrust upon them when it comes to a diagnosis of autism.  Now, it is important to look at the ways a child’s microbiome may become dysfunctional and spiral into autism but is this idea of mom’s gut a true contributor?  Some may say it’s a way to distract from the “environmental” sources of immune dysfunction we seem to be catapulted into these days.  Let’s take a look.

Continue reading "Bad Bacteria in Mom's Gut as Autism Trigger" »


The Thoughts of Chairman Aaronovitch

AaronovitchBy John Stone

David Aaronovitch, recent chair of Index on Censorship, Orwell prize winner and Murdoch poodle (or possibly running dog) writing in the London Times wants to stop people saying things he does not like - so perhaps he will not like this article.

The problem with vaccines, is the more you are not allowed to talk about them the more dangerous they will certainly get. You can be fed lots of reassuring information by the surrogates of the people who manufacture them (the health agencies and mainstream journalists) but until ordinary citizens are listened to you will simply be engaged in an ugly strategy of social repression. It is not good enough to tell people when they have been hurt - or worse when their beloved children have been - that the agencies who did the hurting deny it. But for Aaronovitch the products are not mere fallible industrial products, they are simply beyond public criticism. 

If anybody is expressing unreasonable faith it is he. If he thinks they are safe, what body of science is he citing, and where are the independent agencies? In the UK the licensing agencies are funded by the industry (the MHRA 100%, the EMA 89%), the chair of the vaccine recommendation committee (the JCVI) is director Oxford Vaccine Group which is commercially involved in developing many of the vaccines the committee recommends. These are all perfectly acceptable arrangements to a mainstream media in advanced decline, and no doubt to our lion of free speech.

In his latest article ‘Conspiracy theorists make monkeys of us all’ (The Times 5 July 2018)  Aaronovitch employs all the old bad songs: people who doubt vaccine safety are unscientific and equivalent to those who doubt the theory of evolution; people who doubt vaccine safety are unpleasant right-wing types; people who opposed vaccine mandates in Italy (which incidentally we do not have in the United Kingdom) have caused measles to rise – when he might have focussed on government-pharmaceutical sleaze as the prime cause of their mistrust: the meeting at which Obama put Italian Health Minister Beatrice Lorenzin in charge of global vaccine strategy, the secret deals she signed with GlaxoSmithKline. They probably also knew that she had made up fairy stories about 270 measles deaths among children in London. This was what last year the tens of thousands of people who filled the streets in Italy knew about, unreported by the Italian and global mainstream media, unreported almost certainly in the London Times – just to make them look like idiots. In these circumstances conspiracy was scarcely a theory. Oh yes, and to cap it all they are all “conspiracy theorists”.

Continue reading "The Thoughts of Chairman Aaronovitch" »


Record Cases Of Scarlet Fever In The UK -- Is the Nasal Flu Vaccine Responsible Part IV

Scarlet-fever-quarantine

Part One

Part Two

Part Three

We’ve looked at media reports on SCARLET FEVER in the UK, the use of the nasal influenza vaccine in those locations, and research that shows there are biological mechanisms that could connect the two.  What may need to happen is laboratory research to look specifically at these connections in an honest and scientific manner.

In the United States, there are some considerations to this situation:

Firstly, the CDC does not track SCARLET FEVER:

Image found here  and our thanks.

Scarlet IV

Secondly, the use of FluMist was stopped for two years but is set to resume in Fall, 2018.

ACIP votes down use of LAIV for 2016-2017 flu season, June 22, 2016

CDC panel again advises against FluMist (2017-2018), Wed June 21, 2017

ACIP: LAIV OK to Use During 2018-19 Flu Season, February 26, 2018 03:59 pm

Thirdly, FluMist will NOT be the first and only choice but an option, and it was NEVER administered in schools as it is in the UK.

AAP: Give children IIV flu shot; use LAIV as last resort,  May 21, 2018 : The Academy recommends pediatricians give children inactivated influenza vaccine in the upcoming season and use live attenuated vaccine only as a last resort….Quadrivalent live attenuated influenza vaccine (LAIV4, FluMist), which is given by intranasal spray to healthy patients ages 2 through 49 years, was a popular option for those reluctant to get a shot. While it performed relatively well against influenza B strains, there was modest effectiveness against A/H3N2 strains and no overall effectiveness against A/H1N1 strains. LAIV4 has not been recommended by the AAP and CDC for the past two influenza seasons.

Continue reading "Record Cases Of Scarlet Fever In The UK -- Is the Nasal Flu Vaccine Responsible Part IV" »


Record Cases Of Scarlet Fever In The UK -- Is the Nasal Flu Vaccine Responsible Part III

Scarlet-fever-quarantineIn Part I , we took a look at news articles and data on the increase of scarlet fever in the UK, whilst adding in articles that showed that the LAIV (Live Attenuated Influenza Vaccine) aka the nasal flu shot, has been steadily increased in the UK, in the same time period.

Is it possible that the nasal flu vaccine could somehow result in scarlet fever?  Let’s take a look at research for any connections.

Probably the first fact that needs to be illustrated is -  Influenza infections increase host susceptibility to bacterial infections in a variety of ways

: Viral infections of the upper respiratory tract are associated with a variety of invasive diseases caused by Streptococcus pyogenes, the group A streptococcus…..

With influenza, the one we hear about often is pneumonia.  In 1918, that seems to have been the pattern, that bacteria, not flu, killed millions . Back to scarlet fever.  When penicillin was discovered, the cases and death numbers fell and kept falling. Scarlet fever develops from the organism, S pyogenes, which is classified as a Group A beta-hemolytic streptococcal (GABHS) infection. "Thus, as in the cases of S. pneumoniae and S. aureus, S. pyogenes acts synergistically with influenza viruses and possibly other respiratory viruses in causing secondary bacterial infections. Enhanced adherence and internalization of S. pyogenes to host cells in the presence of influenza virus infection may explain the synergism. 94,95,96

Any form of S. pyogenes infection may potentially lead to systemic manifestations due to release of toxins or superantigens. Scarlet fever typically follows an episode of upper respiratory tract infection,"

Vintage scarlet fever

Vintage illustration online here and our thanks.

Evidence

The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles, December 2015 

Continue reading "Record Cases Of Scarlet Fever In The UK -- Is the Nasal Flu Vaccine Responsible Part III" »


Autism and PANDAS: Parents Knew It and Science Now Shows It

Science post imageBy Theresa Conrick

For years now, parents of children on the autism spectrum have been on the internet and social media sharing their stories.  Many, like me, have had horror stories of their child being sick too often and then abrupt and bizarre behaviors would appear. Strep throat was often a trigger for us.  ---- The strep infection triggers a misdirected immune response causing inflammation within the basal ganglia, a portion of the brain responsible for speech, involuntary movement (tics) and emotion. This inflammation causes an abrupt onset of neurologic and psychiatric symptoms including OCD, tics, anxiety, emotional lability, urinary frequency and sleep disturbances.

While strep is the initial trigger, PANDAS patients can have recurrent symptom exacerbations (flares) later in the disease when exposed to other (non-strep) infections.

We are not crazy.  What we have been living is real and our children are very ill.

Fresh research from my favorite group studying PANS and PANDAS in autism, has their study completed -  and an abstract published - Anti-neuronal and anti-microbial immunity link CaMKII and autism spectrum disorder with pediatric acute-onset neuropsychiatric syndrome .  The full study will be out in late Fall as I had emailed Dr. Cunningham.  She is an awesome researcher and a very compassionate person. She shared that she is involved in similar research, Human anti-dopamine receptor 1 monoclonal autoantibody (mAb) identifies potential mechanisms of neuronal signaling in post-infectious autoimmune-mediated neuropsychiatric disease, and as a result, the full papers are coming out later.  Let’s take a look at the highlights of the asd abstract:

♦  Autism spectrum disorders (ASD) may be associated with neuropsychiatric symptoms such as tics, obsessive-compulsive behaviors, and other symptoms characteristic of pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS).

♦  Functional anti-neuronal autoantibodies which signal CaMKII and induce excess dopamine release were found in ASD/PANDAS serum.

♦  Interestingly, a CamKII mutation has recently been associated with autistic symptoms in animal models and also in ASD in humans. https://www.ncbi.nlm.nih.gov/pubmed/28130356

♦   Children with ASD/PANDAS had significantly elevated anti-neuronal autoantibodies by ELISA, and strong IgG responses against the group A streptococcal epitope GlcNAc were observed in ASD/PANDAS.

Continue reading "Autism and PANDAS: Parents Knew It and Science Now Shows It" »


New Study Links Lowered Probability of Pregnancy in Females 25 - 29 to HPV Vaccination

Empty cribHere is an addendum to this post from the study author, Gayle Delong, PhD:

In connection with my paper, the question has been raised: Given that married women who had the HPV shot were less likely to conceive than those who did not receive the shot, were the former more likely to use birth control than the latter? My result that married women who received the shot were less likely to conceive could be explained if those women were more actively trying to prevent pregnancy than married women who did not receive the shot.

The three questions on NHANES that provide insights into contraception are 1) SXQ251: In the past 12 months, how often had you had sex without a condom? 2) RHD442: Are you taking birth control pills now? 3) RHQ520: Are you now using Depo-Provera or injectables to prevent pregnancy?

I seek to determine whether married women who received the HPV shot are more actively seeking to prevent pregnancy than married women who did not receive the shot. I define “actively seeking to prevent pregnancy” as women who at the time of the interview were using condoms at least half the time or taking the birth control pill or receiving an injectable. I find 51.5% of married women who did not receive the shot and 36.6% of married women who received the shot were actively seeking to prevent pregnancy. The 14.9% difference is statistically significant at the 1% level.

This finding suggests that a greater percentage of married women who received the shot should be conceiving compared with married women who did not receive the shot. However, my original study finds that married women who received the shot are less likely to conceive than married women who did not receive the shot. The finding of my original study is not the result of married women who received the HPV vaccine actively avoiding pregnancy more than women who did not receive the HPV shot. I’m happy to discuss details of my results with researchers who are interested.

A lowered probability of pregnancy in females in the USA aged 25–29 who received a human papilloma vaccine injection

Journal of Toxicology and Environmental Health, Part A, DOI: 10.1080/15287394.2018.1477640

ABSTRACT Birth rates in the United States have recently fallen. Birth rates per 1000 females aged 25–29 fell from 118 in 2007 to 105 in 2015. One factor may involve the vaccination against the human papillomavirus (HPV). Shortly after the vaccine was licensed, several reports of recipients experiencing primary ovarian failure emerged. This study analyzed information gathered in National Health and Nutrition Examination Survey, which represented 8 million 25-to-29-year-old women residing in the United States between 2007 and 2014. Approximately 60% of women who did not receive the HPV vaccine had been pregnant at least once, whereas only 35% of women who were exposed to the vaccine had conceived. For married women, 75% who did not receive the shot were found to conceive, while only 50% who received the vaccine had ever been pregnant. Using logistic regression to analyze the data, the probability of having been pregnant was estimated for females who received an HPV vaccine compared with females who did not receive the shot. Results suggest that females who received the HPV shot were less likely to have ever been pregnant than women in the same age group who did not receive the shot. If 100% of females in this study had received the HPV vaccine, data suggest the number of women having ever conceived would have fallen by 2 million. Further study into the influence of HPV vaccine on fertility is thus warranted.

Gayle DeLong, PhD, is an Associate Professor of Economics and Finance in the Bert W. Wasserman Department of Economics and Finance at Baruch’s Zicklin School of Business. Dr. DeLong has published in leading journals, including Journal of FinanceJournal of Financial EconomicsJournal of International Money and FinanceFinancial Management, and Journal of Financial Research. Research interests include bank acquisitions, regulatory capture, and conflicts of interest. DeLong, the 2013 recipient of the Abraham J. Briloff Prize in Ethics as well as the 2010 recipient of the Zicklin School of Business Teaching Excellence Award, holds a PhD in finance and international business from New York University.

Citation:  Gayle DeLong (2018): A lowered probability of pregnancy in females in the USA aged 25–29 who received a human papillomavirus vaccine injection, Journal of Toxicology and Environmental Health, Part A, DOI: 10.1080/15287394.2018.1477640


Baby Teeth and Autism Prediction

Copper zincSince the number of children being diagnosed with autism continues to increase, the research and studies continue to grow as well.  Many overlap or years later, they are taken to the next level as our understanding of the science increases.  This is such a study. 

From the adapted version on Medpage - Baby Teeth May Predict Autism - Zinc and copper metabolism biomarker may lead to new diagnostic tools

Zinc and copper metabolism cycles in the layers of baby teeth may be able to predict which children will develop autism spectrum disorder, a longitudinal analysis suggests.

This is the first study to generate a 90% accurate fetal and early childhood biomarker of autism by tracking metabolic pathways over time and could lead to new diagnostic tools...the researchers found that children who later developed autism had disrupted zinc-copper rhythmicity in utero or in their earliest months of life...We looked at the naturally shed teeth of children and explored them much as you would explore the growth rings of a tree, using them as a sort of retrospective biomarker to see what children were exposed to in the womb and in early life...Prenatal and newborn children form a new tooth layer daily, which captures an imprint of chemicals circulating in the body and produces a chronological exposure record. Zinc and copper pathways are central regulators of multiple metals; disruption of the pathways may have downstream effects that may affect the metabolism of other essential elements and toxic metals.

TOXIC METALS.  We don’t see those words enough but there are dozens and dozens of studies showing that environmental toxins are connected to the spectrum of autism.

Here is some very good research on the issues of copper/zinc in the human body .

Important theme from the above new, autism study.  Mercury has become a dirty word in autism research. Also that study seems pretty much targeted as a diagnostic tool.   There are thousands of children and young adults who would benefit from research dealing with helping them feel and function better.  Let’s hope there will be more about that. But here we can see that the issue of copper and zinc is not new in autism.  The idea of “disrupted zinc-copper rhythmicity” is new and helpful but let’s look backwards as well:

The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders, May 2009  

The frequency of zinc deficiency, copper toxicity and low zinc/copper in children with autism spectrum disorders (ASDs) may indicate decrement in metallothionein system functioning....The plasma zinc/serum copper ratio may be a biomarker of heavy metal, particularly mercury, toxicity in children with ASDs.

Continue reading "Baby Teeth and Autism Prediction" »


Study: Increased Rates of Cervical Cancer in Sweden Linked to Increase in HPV Vaccinations

HPV-test-alone-OK-cervical-cancer-screening-1440x810(Please see addendum)

Study: Increased Rates of Cervical Cancer in Sweden Linked to Increase in HPV Vaccinations

 

By Brian Shilhavy
Editor, Health Impact News

A new study published in the Indian Journal of Medical Ethics examined cervical cancer rates among women in Sweden and discovered a link between increased cervical cancer rates among women aged 20-49 during a two-year period between 2014 and 2015, corresponding to increased HPV vaccination rates in this population group, years earlier, when mass HPV vaccinations started in Sweden.

Women above the age of 50, during this two-year period, saw no significant cervical cancer increase and were likely too old to have been vaccinated with the HPV vaccine.

Since the study casts doubt on the efficacy of the HPV vaccine, and, in fact, links the vaccine to increased cancer rates, it is highly unlikely you will read about this in the U.S. corporate-sponsored media, where nothing negative about the blockbuster HPV Gardasil vaccine is allowed.

The study was conducted by Lars Andersson, PhD, from the Department of Physiology and Pharmacology at the Karolinska Institute in Solna, Sweden.

Dr. Andersson states that:

…when the Swedish media discussed the increase in the incidence of cervical cancer, the health authorities were unable to explain the increase.

So Dr. Andersson discussed the possibility that mass HPV vaccination rates actually could be the cause of increased rates of cervical cancer:

HPV vaccination could play a role in the increase in the incidence of cervical cancer. About 25% of cervical cancers have a rapid onset of about three years including progression from normal cells to cancer.

Therefore, an increase may be seen within a short period of time.

Gardasil was approved in Sweden in 2006. In 2010, the vaccination of a substantial number of girls started. In 2010, about 80% of the 12-year-old girls were vaccinated.

Combined with 59% of the 13–18-year-old girls vaccinated through the catch-up programme in the same period, one can say that most girls were vaccinated.

Thus, the oldest girls in the programme were 23 years old in 2015; and this is well within the younger age group shown in Fig. 1.

Dr. Andersson points out that even the FDA’s own analysis of Gardasil in 2006 showed a higher risk of “premalignant cell changes” from the vaccine in certain groups that had already been exposed to some HPV strains:

Read more here.

Addendum

Controversy has arisen around the Indian Journal of Medical Ethics article because the author had submitted under a false name to escape professional persecution. After consideration the the journal's editors decided not to retract the article and made the following statement:-

On May 8, the KI informed us that its department of physiology and pharmacology did not have any person of this name and requested us to remove the name of the institution. So, on the same day a correction was carried out and the name of KI was removed and duly intimated to KI.

Since then, we have investigated and learned the identity of the author. The author has said that he used a pseudonym because he believed the use of his real name would have invited personal repercussions from those opposed to any questioning of vaccines.

This deception of the journal’s editors is unacceptable. The author could have asked the editors for confidentiality, giving the reasons. Editors may choose to publish articles without revealing the true name of the author, if it is determined that the circumstances justify it.

However, we considered the matter and decided to keep the article on the site as the issues raised by it are important and discussion on it is in the public interest. The author’s true name is withheld at his request.

 

 


Large Spanish study finds higher rate of pneumonia in vaccinated group (Pfizer's Prevnar 13)

image from www.pharmandorraonline.comThis  study is based on data from middle aged and elderly people echoes the finding of Mawson et al in their pilot study of health outcomes in children (vaccinated vs. unvaccinated) which found "The vaccinated were less likely than the unvaccinated to have been diagnosed with chickenpox and pertussis, but more likely to have been diagnosed with pneumonia, otitis media, allergies and NDD".

Evaluating clinical effectiveness of 13-valent pneumococcal conjugate vaccination against pneumonia among middle-aged and older adults in Catalonia: results from the EPIVAC cohort study

 
  • Angel Vila-Corcoles
  • Olga Ochoa-Gondar
  • Cinta de Diego,
  • Eva Satue,
  • María Aragón,
  • Angel Vila-Rovira,
  • Frederic Gomez-Bertomeu,
  • Ramon Magarolas,
  • Enric Figuerola-Massana,
  • Xavier Raga,
  • Mar O. Perez and
  • Frederic Ballester
BMC Infectious Diseases201818:196

https://doi.org/10.1186/s12879-018-3096-7

Received: 18 December 2017

Accepted: 16 April 2018

Published: 27 April 2018

Abstract

Background

Benefits using the 13-valent pneumococcal conjugate vaccine (PCV13) in adults are controversial. This study investigated clinical effectiveness of PCV13 vaccination in preventing hospitalisation from pneumonia among middle-aged and older adults.

Methods

Population-based cohort study involving 2,025,730 individuals ≥50 years in Catalonia, Spain, who were prospectively followed from 01/01/2015 to 31/12/2015. Primary outcomes were hospitalisation for pneumococcal or all-cause pneumonia and death from any cause. Cox regression models were used to evaluate the association between PCV13 vaccination and the risk of each outcome, adjusting for age, sex and major comorbidities/underlying risk conditions.

Results

Cohort members were observed for a total of 1,990,701 person-years, of which 6912 person-years were PCV13 vaccinated. Overall, crude incidence rates (per 100,000 person-years) were 82.8 (95% confidence interval [CI]: 77.7–88.1) for pneumococcal pneumonia, 637.9 (95% CI: 599.0–678.7) for all-cause pneumonia and 2367.2 (95% CI: 2222.8–2518.7) for all-cause death. After multivariable adjustments we found that the PCV13 vaccination did not alter significantly the risk of pneumococcal pneumonia (multivariable-adjusted hazard ratio [mHR]: 1.17; 95% CI: 0.75–1.83; p = 0.493) and all-cause death (mHR: 1.07; 95% CI: 0.97–1.18; p = 0.190), although it remained significantly associated with an increased risk of all-cause pneumonia (mHR: 1.69; 95% CI: 1.48–1.94; p < 0.001). In stratified analyses focused on middle-aged or elderly persons and immunocompromised or immunocompetent subjects, PCV13 vaccination did not appear effective either.

Conclusion

Our data does not support clinical benefits of PCV13 vaccination against pneumonia among adults in Catalonia. It must be closely monitored in future studies involving more vaccinated person-time at-observation.

THE FULL STUDY CAN BE READ HERE