Kim I did not know that levee history. Absolutely devastating.
My cousin finally understood how I feel when I said
“ you are the white person who the cops are polite to when they stop you. But you didn’t believe Blacks when they say what happens to them til you saw video. You thought it was 1 in a million. You are the person who the doctor can safely stick a needle in. But you don’t believe me when I say what happened to my son.”
I think we ought to encourage all especially vaccine-injury-deniers to videotape their babies round the clock after each series of shots. I don’t want anyone’s child to get harmed but if we had clear video evidence would they finally listen? Would they finally believe a subset can’t tolerate vaccines? Would they finally apologize for their cruel denial? Would they say “But I didn’t know?” Would they apologize for calling the victims of trauma “wackos” for not wanting to be forced to watch their child get reinjured ? Would they call us heros for trying to alert them?

thanks benedetta , that does makes sense about vitamin D. And so sorry to hear of Anita's mom.

Regarding the immune response following vax - if African Americans have a stronger immune response, they would presumably generate more antibodies to self, some of which may be directed at platelet growth factors or perhaps platelets themselves. This loss of platelets leads to thrombocytopenia and blood clots may form in various parts of the body, like the sinuses or digestive track, and can result in death.

I don't want to be the last one to understand clotting but it's still fuzzy. Platelets are key to clotting. So if we take platelets away through antibody actions, it seems like the patient would bleed or bruise, not clot.

I am so sorry for your loss Anita.
God bless you, thinking of you and hugs.

Drymeadow; Vitamin D would be my guess.
But I don't think vitamin D was enough when my son's immune system came up against a DPT vaccine.

Since black Americans are being affected more - the only thing it could be is vitamin D is in lower levels in blacks. Vitamin D, I was told is really not a vitamin but more of a cortisone hormone that reduces inflammation.

Did they not notice that those with low vitamin D levels had bad out comes with covid disesae?

And then vaccines cause inflammation as well.

We all are on the verge of the same health problems, all depending on a vitamin D being up to a level to save us?

DMX a very sad loss to all, a great talent and of course you can bet your pharma cash cow on it, its nothing to do with vaccines e-v-e-r!!

It's raining, it's pouring
The old man is snoring
He went to bed
And he bumped his head
And he couldn't get up in the morning

Very sad to see when your sister is part of the brain washing..washed..

The sister of a man who died from a blood clot on the brain after having the Oxford-AstraZeneca vaccine says she "strongly believes" people should keep having the Covid jab.

Neil Astles, 59, a solicitor from Warrington, Cheshire, died on Sunday. He was vaccinated on 17 March.

Pharmacist Alison Astles told the BBC that doctors were "99.9% sure" the clot was due to the jab.

But she said he was "extraordinarily unlucky" and the risk was "very low".

Dr Astles said she felt she had a responsibility to speak out "because, overall, we will save more lives by people having the vaccine than not".

The family is still awaiting a report from the coroner on Mr Astles' cause of death.

https://www.bbc.co.uk/news/uk-56675665

Pharma For Prison

MMR RIP

This points up an issue with VAERS.
My mom at 87 tested positive for Covid twice including November 2020. In late December 2020 she got the first Pfizer vaccine and fell a few days later. On Jan 14 she got the 2nd Pfizer vaccine and fell 4 times refused to eat developed a UTI and died 8 days later. The way VAERS shows it she died 33 or so days after first shot. That doesn’t look as obvious. But she died only 8 days after the 2nd shot and the form is designed in a way that obscures this . I posted this elsewhere about Midwin’s tragedy. I would like to know what shot was involved here .

drymeadow, this is one article on a possible explanation for why the adenovirus vector vaccines are causing blood clots. It is possible that the S-protein is a separate issue--I guess (as the scientist near the end of the article says) we would need to see a lot more humans being harmed and have a lot of autopsies in order to parse the different etiologies of vaccine-induced blood clotting. What does seem to be a distinct possibility is that there is an autoimmune problem caused by the AZ and JandJ shots that is different from what the virus does, and what the Pfizer and Moderna shots do. Of course, it is guesswork, as one would expect for an experimental product.

Theresa O'Brien

6:35 AM (3 hours ago)

to Joe
two pieces:

https://www.medpagetoday.com/special-reports/exclusives/92022

From VIPIT to VITT: Thrombosis and COVID Vaccines

— More data support link between adenovirus vector vaccines, blood clotting, and low platelets

by Veronica Hackethal, MD, MSc, Enterprise & Investigative Writer, MedPage Today April 9, 2021

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A computer rendering of a blood clot and covid-19 viruses in the bloodstream

Following up on previous reviews of the evidence, the European Medicines Agency (EMA), WHO, and Britain's Medicine's and Healthcare Products Regulatory Agency (MHRA) have issued statements saying that the overall benefits continue to outweigh the risks of very rare blood clots with low platelets reported after the AstraZeneca COVID-19 vaccine.

The WHO now states that a causal relationship is "considered plausible but is not confirmed," while the MHRA has said that the evidence is now "stronger" for a link between the vaccine and these events. The EMA calls these "unusual blood clots with low platelets" and says they should be listed as very rare side effects of the vaccine.

How Rare Are These Clots?

As of April 4, 169 cases of cerebral venous sinus thrombosis (CVST) and 53 cases of splanchnic vein (which drains blood from the digestive system) thrombosis have been reported in the European drug safety database. About 34 million doses of the AstraZeneca vaccine have been administered in Europe and the U.K., according to Sabine Straus, chair of the EMA's Pharmacovigilance Risk Assessment Committee (PRAC), as quoted by science journalist Kai Kupferschmidt in a tweet from an EMA press briefing.

The reported rate "varies very much with how good the reporting system in a member state is and how good cases are being identified.... In Germany, a lot of work has been done and I think there is a reporting rate of 1 in 100,000," Straus said at the briefing, according to Kupferschmidt.

The MHRA statement put the overall risk of these types of clots at about 4 per million recipients of the AstraZeneca vaccine. The agency said it had received 79 reports of blood clots with low platelets among 20.2 million doses of the AstraZeneca vaccine in the U.K., as of March 31. Of these, 44 were CVST and 35 were thromboses in major veins. These events occurred among 51 women and 28 men ages 18 to 79 years, among whom 19 died (13 women, 6 men). Of those who died, 11 were under age 50, and three were under 30. Fourteen had CVST with thrombocytopenia and five had thrombosis with thrombocytopenia.

In its statement, the EMA says that the PRAC reviewed 62 cases of CVST and 24 cases of thrombosis in the splanchnic vein reported in EudraVigilance (the European drug safety database), as of March 22. Most cases were in women under age 60 years, and most occurred within two weeks of the first dose of the vaccine. Eighteen people died.

On Friday, the EMA said the same problem may be occurring with the Johnson & Johnson vaccine, which, like AstraZeneca's, uses an adenovirus vector to deliver genetic code for coronavirus antigens. The agency said it had reports of three clotting episodes out of some 4.5 million people receiving the J&J product. It had not yet determined a cause-and-effect relationship, however.

Notably, the mRNA vaccines from Moderna and Pfizer/BioNTech have not been linked to excess thrombosis episodes.

What Is the Explanation?

With regard to the AstraZeneca investigation, EMA said one "plausible" explanation for the phenomenon is that the vaccine may trigger an autoimmune immune reaction leading to an "atypical heparin-induced-thrombocytopenia like disorder," for which specific risk factors have yet to be identified.

Shortly after these problems started to surface, researchers in Germany and Norway quickly identified an autoantibody called platelet factor 4 antibody that appeared to be linked to the syndrome. Platelet factor 4 antibody causes heparin-induced thrombocytopenia (HIT), a rare clotting disorder that affects 1%-2% of people after exposure to heparin. In rare cases, platelet factor 4 antibody has been associated with CVST.

On April 9 2021, the German team lead by Andreas Greinacher, MD, PhD, of the Medical University of Greifswald in Germany, published a case series about the issue in the New England Journal of Medicine. It included 11 patients in Germany and Austria who presented with unusual thromboses and moderate to severe thrombocytopenia, five to 16 days after receiving the AstraZeneca vaccine. None of these patients had received heparin in the past. Nine were women, and the median age was 36 (range 22-49). Five patients had more than one clotting event: nine had CVST, three had splanchnic vein thrombosis, three had pulmonary embolism, four had other thromboses, and five had disseminated intravascular coagulation (DIC). Six patients died.

The researchers also did platelet activation assays on 28 patients who developed thrombosis and thrombocytopenia after receiving the AstraZeneca vaccine, and who tested positive for antibodies against platelet factor 4. Results showed increased platelet activation in the presence of platelet factor 4, which was inhibited with immune globulin.

Greinacher and colleagues wrote that the disorder "resembles" severe HIT, but "unlike the usual situation" none of these patients received heparin in the past. They noted that autoimmune or spontaneous HIT can occur without exposure to heparin, and is characterized by "unusually severe thrombocytopenia, increased rates of DIC and atypical clots." They concluded that the AstraZeneca vaccine can result in a rare syndrome that "clinically mimics autoimmune heparin-induced thrombocytopenia," and propose using the term "vaccine induced immune thrombotic thrombocytopenia" (VITT) to avoid confusion.

In a past publication, Greinacher and colleagues had referred to this syndrome as vaccine-induced prothrombotic immune thrombocytopenia (VIPIT).

Concurrent with the German team, the Norwegian team published a case series, also in the New England Journal of Medicine, involving five patients with this syndrome after the AstraZeneca vaccine; they also proposed to call it VITT. All patients in this series had high levels of platelet factor 4 autoantibodies without past exposure to heparin. Five had major cerebral thrombosis, and three died.

"These results strengthen the view that vaccination may have triggered the syndrome," wrote Nina H Schultz, MD, PhD, of Oslo University Hospital, and colleagues. "Although rare, VITT is a new phenomenon with devastating effects for otherwise healthy young adults and requires a thorough risk-benefit analysis."

Unusual Clots?

What is striking about VITT is that the brain and abdomen are atypical locations for clots to develop. COVID-19 infection itself can cause autoimmune associated thrombocytopenia and thrombosis, but the majority of those clots are deep venous thromboses (DVTs) and pulmonary embolism (PE). Thrombocytopenia has occurred with other vaccines, but in these cases, low platelets are associated with bleeding, not clots, according to Rajiv Pruthi, MBBS, a hematologist at the Mayo Clinic in Rochester, Minnesota.

"CVST is a distinctly unusual location for a blood clot that is associated with low platelets," he told MedPage Today.

Right now, explanations for these phenomena are "pure speculation," Pruthi said. However, he noted that lower extremity veins belong to different vascular beds than those in the abdomen and brain, and different vascular beds may express different proteins that play a role in clot development. The idea of vascular bed-specific hemostasis is not new, and may play a role in clot formation in different areas of the body.

"I wonder if that has something to do with this," he said. "I'm hoping we'll see more of this going forward, but it's hard to study vascular beds anywhere short of doing a biopsy. I don't think anyone would want to do a brain biopsy."

Reactions and Recommendations

Many countries in Europe have reacted by placing age restrictions on the AstraZeneca vaccine, and these vary by country. For example, Germany and the Netherlands have limited the vaccine to people over age 60; France set age 55 as the threshold. Britain's Joint Committee on Vaccination and Immunisation has advised that people under age 30 without underlying medical conditions should be offered a different vaccine. Norway has halted vaccinations altogether, at least for now. Elsewhere in the world, Canada, Australia, and the Philippines have also imposed age restrictions.

Meanwhile, the U.K.'s Expert Haematology Panel has offered guidance for diagnosis and management of these very rare events, as did Greinacher and colleagues in their NEJM publication. In probable cases, they recommend urgent use of IV immunoglobulin, use of non-heparin anticoagulants, and avoidance of platelet transfusions. They added that vitamin K antagonists (e.g., warfarin) are contraindicated in acute thrombocytopenia and DIC.

"The EMA and WHO didn't really come out and say it, but I think the conclusion is that if you're seeing these unusual thromboses with low platelets after COVID-19 vaccination, you might want to avoid heparin. That's the go-to drug for all thromboses but in this situation, think about a different treatment," Pruthi emphasized.

Veronica Hackethal reports for MedPage Today's Enterprise and Investigative journalism team. Follow

It is starting to look that way. Why so many black Americans ? And what's up with this spike protein and major cardiovascular events ? If the protein itself is causing CV events, mass producing the protein inside the body may not be such a hot idea. Does anyone have a paper that slipped through the pharma firewall explaining this ?

When the levee breaks I'll have no place to stay