Principal Controversies in Vaccine Safety in the United States
Drs DeStefano and Offit are authors.
Accepted Manuscript
Principal Controversies in Vaccine Safety in the United States
Frank DeStefano, MD, MPH Heather Monk Bodenstab, PharmD Paul A Offit, MD
Clinical Infectious Diseases, ciz135, https://doi.org/10.1093/cid/ciz135
Read the full Manuscript here.
ABSTRACT
Concerns about vaccine safety can lead to decreased acceptance of vaccines and resurgence of vaccine-preventable diseases. We summarize the key evidence on some of the main current vaccine safety controversies in the United States, including:
1) MMR vaccine and autism;
2) thimerosal, a mercury-based vaccine preservative, and the risk of neurodevelopmental disorders;
3) vaccine-induced Guillain-Barré Syndrome (GBS);
4) vaccine-induced autoimmune diseases;
5) safety of HPV vaccine;
6) aluminum adjuvant-induced autoimmune diseases and other disorders; and
7) too many vaccines given early in life predisposing children to health and developmental problems.
A possible small increased risk of GBS following influenza vaccination has been identified, but the magnitude of the increase is less than the risk of GBS following influenza infection. Otherwise, the biological and epidemiologic evidence does not support any of the reviewed vaccine safety concerns.
You can comment on this article at the site. Please feel free to add your own interpretation of the statements made in this manuscript in our comments. Some immediate content questions:
Autism is a neurodevelopmental condition that has a strong genetic component and whose genesis begins in utero. WORD SALAD: Where is the citation and/or incontrovertible proof? Here is a recent article on regressive autism. No genetics mentioned.
The authors found no sudden change in the incidence of autism after introduction of MMR vaccine and no association between receipt of the vaccine and development of autism. WORD SALAD: "sudden" and "receipt". Autistic regression takes place over time.
Ethylmercury is broken down and excreted much more rapidly than methylmercuryand is thereforemuch less likely to accumulate in the body and cause harm WORD SALAD: "less likely" is hardly scientific nor reassuring. WORD SALAD: Thimerosal is the "safe" mercury... read The Comparable Dangers of Ethylmercury and Methylmercury
Benedetta,
You're so right. Yesterday in the UK (and around Europe) thousands of our schoolchildren left their schools to take to the streets in protest against the lack of action by governments to address the destruction of the planet. I have often wondered why the generations which followed mine were not revolting while they were at school or university. Perhaps this generation will set a new example to us all. I myself have my T-shirts at the ready but there has never been a march for any of the causes I'm involved in. I have not even been able to make contact with any activists in the field of vaccine poisoning in Scotland or the UK. Where do I find them, other than on the internet? (I know about Angus, but that's only the two of us!)
Posted by: Grace Green | February 16, 2019 at 06:07 AM
Hans Litten said maybe it is time for torches and pitchforks. We all feel that way. There is this undercurrent in our society of rage; I feel it finally in the younger generations of parents.
Posted by: Benedetta | February 15, 2019 at 11:47 AM
I would add lack of testing for mutagenicity and carcinogenicity.
I would add unwillingness to value the health of the individual over making changes to the vaccine program.
I would add lack of pursuit of Paul Thorsen.
I would add severe control of media.
I would add persecution of Dr Wakefield.
I would add persecution of Dr Sears, and Drs who grant exemptions.
I would add a lack of proper judicial process in Vaccine Court in the US.
Posted by: greyone | February 15, 2019 at 09:03 AM
they left out death. (SIDS).
they left out retroviruses.
they left out changes to brain, immune, neurological, and gastrointestinal systems.
Posted by: greyone | February 15, 2019 at 08:38 AM