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Pentavalent Vaccine - Doctors Raise Red Flag

PV vaxBy Jacob Puliyel MD MRCP M Phil

New Delhi, India

14 March 2018.

Pentavalent vaccine (PV) that was introduced by India six years ago doubled the deaths of children soon after vaccination compared to DPT (Diphtheria-Pertussis- Tetanus) vaccine according to a new study that calls for a "rigorous review of the deaths following vaccination with PV."

Government records show that there were 10,612 deaths following vaccination in the last 10 years. The Health Ministry has promised to study the huge increase in 2017. The present analysis could be a starting point in the quest to reduce the numbers of such deaths.

The study by Dr Jacob Puliyel, Head of Pediatrics at St Stephens Hospital and Dr V. Sreenivas, Professor of Biostatistics at the All-India Institute of Medical Sciences, both in New Delhi, is published in the peer-reviewed Wolters Kluwer Health’s journal, Medical Journal of Dr D Y Patel University.

PV is a combination of DPT vaccine and two more vaccines against Haemophilus influenza type B (Hib) and hepatitis B.  Starting December 2011, PV was introduced into India's immunization programme to replace DPT vaccine in a staged manner with a view to adding protection against Hib and Hepatitis B without increasing the number of injections given to infants. 

But sporadic reports of unexplained deaths following immunization with PV had been a matter of concern.  Puliyel, Sreenivas, and their colleagues undertook the study to find out if these deaths were merely coincidental or vaccine induced.

The authors obtained data of all deaths reported from April 2012 to May 2016 under the Right to Information Act. Data on deaths within 72 hours of administering DPT and PV from different states were used. 

For their study, the authors assumed that all deaths within 72 hours of receiving DPT are natural deaths. Using this figure as the baseline, they presumed that any increase in the number of deaths above this baseline among children receiving PV must be caused by this vaccine.  

If a state introduced PV in 2014, then data on DPT doses PV doses and deaths following vaccination were noted from that year on. This ensured that the deaths were all reported from the state using the same surveillance system.

According to their analysis of the data provided by the government, there were 237 deaths within 72 hours of administering the Pentavalent vaccine (PV) -- twice the death rate among infants who received DPT vaccine.   

Extrapolating the data, the authors have estimated that vaccination of 26 million children each year in India would result in 122 additional deaths within 72 hours, due to the switch from DPT to PV. 

"There is likely to be 7020 to 8190 deaths from PV each year if data from states with the better reporting namely Manipur and Chandigarh are projected nationwide," their report says.

The authors note that while the study looks at the short-term increase in deaths (within three days of vaccination) it does not calculate the potential benefits of PV on infant mortality, for example by protection against lethal diseases like Haemophilus influenza.

In spite of the data presented in this paper from a large cohort, the authors point out that the evidence is merely circumstantial and not conclusive. "These findings of differential death rates between DPT and PV do call for further rigorous prospective population-based investigations," the study concludes. (END)

[This press release has been written with help from an experienced science reporter]

The article can be accessed here.

 

 

 

 

Jacob Puliyel MD MRCP M Phil

puliyel@gmail.com

Comments

michael

Question: Is the DPT given in India and other locations the whole cell with 3,000 antigen units and mercury?

Angus Files


Eindecker,
“further establishing that vaccination of children in developing countries can protect them from a potentially fatal yet preventable disease .”

Why is it India has cut its ties with Bill Gates chief pharma sales man?

https://www.reuters.com/article/us-india-health-bmgf/india-cuts-some-funding-ties-with-gates-foundation-on-immunization-idUSKBN15N13K

“The decision is seen as part of India’s broader clampdown on non-governmental organizations to assert control over decision making in key policy areas. Last year, India ordered the dismissal of dozens of foreign-funded health experts working on public welfare schemes.”

Why is it that they are having to force vaccinate India as with more and more countries of the world?
https://www.thenewsminute.com/article/tn-govt-wants-make-measles-rubella-vaccine-mandatory-legal-we-ask-experts-57934

“Facing stiff opposition from parents regarding the administration of the MR (Measles-Rubella) vaccine for children under the age of 15 in Tamil Nadu, Health Minister C Vijaya Baskar has said that the government will make the vaccine mandatory in the state.”

We know don’t trust your own eyes, rely only on .Gov .pharma paid studies.Pharma knows best how to control the population, thinning required that`s whats being pushed..

Pharma For Prison
MMR RIP

Morag

It's human beings that are being damaged and injured in the study data ."Not farmed salmon"
See .A disgrace.Ten million salmon thrown away by fish farming industry Oct 2017
www.heraldscotland.com
The common denominator appears to be industry denial of chilling failures with bottom line profit margins at any cost ? East India Company ,Business Model continues?
The unsinkable ,absolutely unsinkable Titanic mentality still running amock.
See US Navy Vs Spanish Lightouse You tube .
"Vaccine vessels heading right for the rocks"

annie

Thank you! Thank you! Thank you! Dr Pulliyell!!!!!!!!! Happy st Patrick's Day!!!! And all of the rest of ya can piss off!

go Trump

pharmster

Very well written 4 Rules & conclusion, Thank you.

... sooner or later a pharmaceutical company that gets large enough has to stop producing effective treatments and increase profits by making people sick. There is really no other way.

John Stone

Eindecker

The problem is whether the serious adverse events were really rare. No?

Jenny Allan

Similar 'circumstantial' infant deaths after pentavalent vaccines in Canada:-
https://vaccinechoicecanada.com/in-the-news/can-infanrix-hexa-kill-babies/

Jenny Allan

The problem seems to be the original article is behind a paywall in the journal.
Try this one:-
http://jacob.puliyel.com/paper.php?id=419

Eindecker

Please post this amended version without the error in the reference:
On the other hand Angus & John http://www.livemint.com/Home-Page/cUsGyENeoqLU5uFgxorQ2I/India-saw-most-deaths-due-to-respiratory-illnesses-in-childr.html
India registered the highest number of deaths among children under five years of age, due to respiratory illnesses in 2015, a Lancet study has revealed.
Lower respiratory tract infections (LRIs) such as Pneumococcal pneumonia, Haemophilus influenzae type b (Hib), Respiratory syncytial virus and Influenza are a leading cause of morbidity and mortality, particularly in children younger than five years.
In India, about 82,448 children died of Pneumococcal pneumonia, 20,987 deaths were attributed to Haemophilus influenzae type b (Hib)
Effectiveness of Hib vaccination https://www.ncbi.nlm.nih.gov/pubmed/16491301
From eight trials, the protective efficacy of the Hib conjugate vaccine was 84% (OR 0.16; 95%CI 0.08-0.30) against invasive Hib disease, 75% (OR 0.25; 95%CI 0.08-0.84) against meningitis, and 69% (OR 0.31; 95%CI 0.10-0.97) against pneumonia. Serious adverse events were rare. The results provide firm evidence that Hib conjugate vaccines are safe and effective in reducing the risk of all forms of invasive Hib disease, further establishing that vaccination of children in developing countries can protect them from a potentially fatal yet preventable disease .

Paul Thomas

Twice after this vaccine came out my clinic tried it and both times there was a significant jump in patient calls about side effects. I stopped using it within weeks of trying it both times. This information does not surprise me. There is something very wrong with this combo vaccine.

pharmster

-----
Big Pharma Business Strategy 101:

Rule 1) Only create drugs that do not work well or not work at all:

- A product that really works will destroy your market over the long term. When your patents expire it will be hard to create an even more effective drug, society will continue to use the old drugs, you killed demand for future sales and your profits will decline and you will go under. If you want to survive create useless drugs and lots of them.

Rule 2) It is easier to create an ineffective treatment and lie about the efficacy than to create an effective treatment

- Real discoveries are rare but you can invent a scam every month of the year if needed, provided you have mastered the art of deceit. You are not in the science or medical business. You field is psychological manipulation. You manipulate patients, doctors, scientists, politicians, society. You know their weaknesses and how to make them do what you want them to do.

Rule 3) If you want not just to survive but increase your profits and thrive you need more sick people.

- Revenue growth can not happen if you just create ineffective treatments. You need harmful treatments for growth. Treatments that make people permanently ill. Vaccines are a very suitable product for that purpose. Statins and SSRIs have a lot of potential too.

Rule 4) The maximum revenue is reached at the point where there are as many sick people as society and economy can support.

-If too many people are disabled and society is unable to pay for them, your profits will decline, if there are not enough sick people your revenue is not optimized. Aim for the sweet spot.

----

These are just basic "business" principles, the reality of the industry. From them one can deduct that sooner or later a pharmaceutical company that gets large enough has to stop producing effective treatments and increase profits by making people sick. There is really no other way. Since every for-profit enterprise needs to grow, this tragedy is inevitable. If they do not do it, someone else will take their place and they will be replaced by someone more ruthless.

Linda1

Thank you John! :)

John Stone

Linda,

I have replaced the link with one to a contents page which might be more stable.

John

Linda1

John,
Nope. I wonder if it is geographical (and political) difference in access.

John Stone

When I replaced the links earlier today, they worked. It maybe better to go this page and download pd from there:

http://www.mjdrdypu.org/downloadpdf.asp?id=226012;type=2

Linda1

Sorry should have checked Tim's links before posting my last comment. Those bring me to the same page as the ones at the end of the AOA article (page not found).

Linda1

John,
Both links are titled: "Medical Journal of Dr. D.Y. Patil Vidyapeeth"
then this (no article):

"Page not found Page Not Found
Sorry the page you were looking for has either been changed or moved or the URL was incorrectly entered.
If you clicked on a link to get here you may wish to inform the webmaster of the page linked to this page.
Following links may help you to locate the page you were looking for"

Will check out the link that Tim posted, but just letting you know.

Angus Files

Very brave for the Dr`s to stand up to what they have found. Back in 2010 Dr Jacob Puliel was being named and shamed as "anti-vaccine" .True to form Pharma shaming anyone who speaks out but hats off to Dr Jacob for standing his ground....

the BMJ
http://www.bmj.com/rapid-response/2011/11/02/sri-lankan-deaths-following-pentavalent-vaccine-acceptable-collateral-dama

07 July 2010
Jacob Puliyel
Head of Pediatrics
KB Saxena, Debabar Banerji, Imrana Qadeer, NJ Kurian, Ritu Priya , Mira Shiva and Gopal Dabade.
St Stephens Hospital

Sri Lankan deaths following Pentavalent vaccine: Acceptable collateral damage?
As a group of pediatricians, health care activists, teachers in
Public Health and bureaucrats who have championed the cause of universal
immunization in India all our working lives, we were taken aback at being
described as ‘anti-vaccine’, in the print version of the BMJ (1). We plead
for the right to respond in our defense, in the print version.
India is a country where 50% of the population, (mostly poor living
in remote rural areas) do not receive the 6 basic vaccines in the EPI,
namely BCG, DPT, OPV and measles vaccine. The incremental cost of complete
immunization is less than US $1 (Rupees 30) per child. Every Rupee we can
mobilize, we need to invest to ensure that all babies in India get this
basic right. The push to include newer vaccines into the routine
immunization schedule must be viewed in this context. The ‘pentavalent
vaccine’ that is being canvassed, on its own, will increase cost of DPT
immunization twenty-fold. It stands to reason that these new vaccines will
be taken up mostly by the urban privileged and there will be even less
available for the rural poor."

Read More Link Above...

Pharma For Prison

MMR RIP

Tim Lundeen

You can get a PDF of the article from http://www.mjdrdypu.org/downloadpdf.asp?id=226012;type=2

Or go to http://www.mjdrdypu.org/aheadofprint.asp, scroll down to the "Deaths reported after pentavalent vaccine compared with death reported after diphtheria-tetanus-pertussis vaccine: An exploratory analysis" article, use the links there.

Jeannette Bishop

Is the DPT vaccine they are using for comparison here the same DPT vaccine that had a mortality rate ten times higher than that of the not-yet-vaccinated in Guinea Bissau?

Also, I wonder if India is already "benefitting" from the rise in non-capsulated haemophilus bacteria and other disease shifting and rising replacements we've seen in the U.S. from the use of HIB and pneumococcal vaccines? If so, what good does the HIB vaccine do them, and if not, what good will the HIB vaccine do them?

Frankly, I think a worldwide moratorium should be placed on all killed infant vaccinations until they perform COI-free mortality baseline research of the not vaccinated, or inform clearly parents who want any of these vaccines that there is evidence suggesting they may be giving their infants a vaccine that increases the chance of sickness, disability, and death, while there is little evidence they are getting a matching benefit from said vaccine, at least until such research is performed.

Aimee Doyle

@Bob

Love that - "further rigorous yadda, yadda, yadda" - I'm going to remember that line! It made me laugh, although it is sort of gallows humor.

Rebecca Lee

The deaths within 72 hours of the injection are probably the tip of the iceberg as far as injury goes. I bet there are a whole lot of other things that happened to the kids that survived.

John Stone

The original someone

I don't know what was wrong, I have renewed the links and it appears to be OK now.

The Original Someone #1

Looks like the links to articles at the bottom of this post were already taken down at the site. I hope that the study still appears online somewhere so we can view it.

bob moffit

"In spite of the data presented in this paper from a large cohort, the authors point out that the evidence is merely circumstantial and not conclusive. "These findings of differential death rates between DPT and PV do call for further rigorous prospective population-based investigations," the study concludes."

(Every time I hear calls for "further rigorous prospective population-based investigations" .. I am immediately reminded of Sienfeld's characters .. Elaine and George .. whenever they spoke of actions they had taken but were too embarrassed to reveal .. simply mumbled "yadda, yadda, yadda" .. which to me .. is no different than "further rigorous yadda, yadda, yadda")

In any event ... aren't the children of India lucky to have these courageous authors "qualify" their findings as "merely circumstantial and not conclusive" .. meaning there is absolutely no urgency after .. "extrapolating the data, the authors have estimated that vaccination of 26 million children each year in India would result in 122 additional deaths within 72 hours, due to the switch from DPT to PV."

Though I will NEVER understand it .. I none-the-less get it .. protecting the "herd" is far more beneficial to India .. and .. those anticipated 122 additional deaths are nothing more than "collateral damage" .. to be accepted as the consequences of "good intentions" gone horribly awry.

I am sure all involved feel terrible that 122 children will likely die .. but .. always remember .. they died PROTECTING THE HERD.

(Consider this shallow explanation for why India embraced the idea of combining the DPT with HIB & HEP in December 2011 .. "to add protection against Hib and Hepatitis B without increasing the number of injections given to infants."

I suspect all involved sleep peacefully at night knowing their decision to "add protection against HIB and HEP B" .. was made in the "best interests of the children" .. which was ..reducing the number of injections given to infants.)

AND THE BAND PLAYS ON AND ON, ON AND ON.....

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