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Best of AofA: There’s a Funny Thing About Evidence: More Support for Autism-Mercury Link

Science_jpg_w300h345 Robert F. Kennedy's book is shipping - debut date is August 4. Thimerosal: Let The Science Speak. Have you ordered a copy?  Be sure to leave a review after you read the book. It's quite helpful to an author - and the audience he wishes to reach.  Thank you. The post below ran in 2010.

"...thimerosal at the same concentrations received in human infants had clearly measurable effects on opioid receptor development in the infant rats. They also found that these effects were stronger at higher doses. The effect was found to be persistent, lasting well beyond the initial period of administration. According to the authors, “very likely, it is permanent.”"


By Mark Blaxill

Despite the relentless drumbeat of propaganda from the CDC, public health authorities and the thuggish on-line goons of the medical industry, there’s a funny thing going on. The evidence of a connection between mercury exposure and autism keeps growing.

Last month, two scientists at the University of Northern Iowa, Catherine DeSoto and Robert Hitlan, published a fascinating review paper (see HERE for an interview with DeSoto; also see HERE and HERE for earlier reviews of DeSoto’s successful debunking of an error-filled paper on autism and mercury). They asked a simple question: what does the published evidence linking autism and mercury really say? To answer that question, they did a simple Pub Med search. They searched for the terms “(Autism AND Mercury) OR (Autism AND Heavy Metals)”. They found 163 articles (a number that has since risen to 174) and reviewed them. According to the authors, “Of these 163 articles, 58 were research articles with empirical data relevant to the question of a link between autism and one or more toxic heavy metals. Fifteen were offered as evidence against a link between exposure to these metals and autism. In contrast, a sum of 43 papers were supporting a link between autism and exposure to those metals.” In short, 74% of the published studies supported the theory.

Evidence is a funny thing.

Last week, yet another important study was published with no fanfare in the mainstream media. A research team in Warsaw led by Dr. Dorota Majewska published the latest findings from their ongoing investigation of the effect of thimerosal administration on newborn rats. I wrote about the first published findings from this project HERE. In their latest paper, the authors extended their investigation of the potential relationship between thimerosal and the development of opioid receptors in the infant brain. They found that thimerosal at the same concentrations received in human infants had clearly measurable effects on opioid receptor development in the infant rats. They also found that these effects were stronger at higher doses. The effect was found to be persistent, lasting well beyond the initial period of administration. According to the authors, “very likely, it is permanent.”

Should it surprise anyone that thimerosal administration in low doses is dangerous to infant brain development? So far, we’ve seen this result repeated reliably in rats, hamsters, mice and monkeys (the single animal study that has not reproduced this finding was NIH-funded).  It’s obvious to these researchers what many of us have argued for years, that giving mercury to infants on purpose is stupid. In a similar spirit, the Warsaw team closed their paper with the following observation.

In conclusion, this study documents that parenteral administration of [thimerosal] to suckling rats at doses equivalent to those used in pediatric vaccines or higher produces lasting alterations of [mu-opioid receptors ] in several brain regions and damage to neurons. If analogous changes occur in the brains of some children, they are likely to have profound neurological, physiological and behavioral consequences, which may be relevant for certain neurodevelopmental disorders. These data argue for removal of [thimerosal] from all infant vaccines.

I couldn’t have said it better myself.

Mark Blaxill is Editor-at-Large for Age of Autism and a director of SafeMinds. His new book, co-authored with Age of Autism Editor Dan Olmsted, The Age of Autism: Mercury, Medicine and a Man-Made Epidemic will be published next week.

The abstract of the Warsaw team’s article is below. The full article is available free HERE.

Neurochem Res. 2010 Aug 28.
Neonatal Administration of Thimerosal Causes Persistent Changes in Mu Opioid Receptors in the Rat Brain.

Olczak M, Duszczyk M, Mierzejewski P, Bobrowicz T, Majewska MD.

Department of Pharmacology and Physiology of the Nervous System, Institute of Psychiatry and Neurology, Sobieskiego 9 str., 02-957, Warsaw, Poland.

Abstract
Thimerosal added to some pediatric vaccines is suspected in pathogenesis of several neurodevelopmental disorders. Our previous study showed that thimerosal administered to suckling rats causes persistent, endogenous opioid-mediated hypoalgesia. Here we examined, using immunohistochemical staining technique, the density of mu-opioid receptors (MORs) in the brains of rats, which in the second postnatal week received four i.m. injections of thimerosal at doses 12, 240, 1,440 or 3,000 mug Hg/kg. The periaqueductal gray, caudate putamen and hippocampus were examined. Thimerosal administration caused dose-dependent statistically significant increase in MOR densities in the periaqueductal gray and caudate putamen, but decrease in the dentate gyrus, where it was accompanied by the presence of degenerating neurons and loss of synaptic vesicle marker (synaptophysin). These data document that exposure to thimerosal during early postnatal life produces lasting alterations in the densities of brain opioid receptors along with other neuropathological changes, which may disturb brain development.

Comments

Jim Thompson

The CDC buys and distributes heavy metal preserved flu vaccines containing 50 parts per million mercury for children. See http://www.ageofautism.com/2013/08/the-cdc-buys-and-distributes-heavy-metal-mercury-preserved-flu-vaccines-for-children.html .

That level is 250 times higher than the USEPA level for D009 mercury hazardous waste. See http://www.ageofautism.com/2009/12/q-a---how-about-a-half-cup-of-mercury-hazardous-waste.html .

That level is 25 thousand times higher than the USEPA recommended maximum level in drinking water of 2 parts per billion in drinking water. See http://water.epa.gov/drink/contaminants/basicinformation/mercury.cfm

This injection of a known neurotoxin into children (and pregnant women) continues 15 years after the Unites States Public Health Service, the American Academy of Pediatrics (AAP), and vaccine manufacturers agreed that thimerosal-containing vaccines should be removed as soon as possible. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm4826a3.htm

Please contact your elected US Senators and Representative. See http://www.usa.gov/Contact/Elected.shtml . Ask them to stop the use of our tax dollars by the CDC to buy and distribute Thimerosal (heavy metal mercury) preserved flu vaccines for children.

Eileen Nicole Simon

The brain must be the focus of research on autism. The mu-opioid receptor changes were found in the “dorsal peri-aqueductaltal gray” and nuclei of the basal ganglia.

These are among the areas of highest blood-flow and metabolism in the brain. They are also sub-cortical sites important for ongoing postnatal maturation of the cerebral cortex. The same sites are also damaged by asphyxia at birth, and complications at birth have been documented more often than any of the other known causes of autism.

The “inferior colliculus” is the site of most severe damage caused by asphyxia. This is a term I like to put in PubMed followed by, mercury, valproate, neurofibromatosis, mitochondrial, bilirubin, serotonin, “gamma-amino butyric acid”, etc.

Anita Yvonne Donnnelly

i keep thinking that we need to do what the vietnam war protesters did, even though it took another 4 years to get out of the war, even though LBJ possibly had good intentions but bad information.

"LBJ LBJ how many kids did you kill today?"

CDC CDC Toxin-filled shots are a travesty
CDC CDC Brain damage with your complicity
CDC CDC Autism is a catastrophe
CDC CDC Criminally tied to the industry
Kathleen S, will not hear,
Is it pride or is it fear?
Kathleen S, will not heed,
Is it fear or is it greed?
HHS, HHS full of lies
Autism still on the rise
HHS, HHS
You are censoring the press
HHS vaccine-armed
child after child harmed.
HHS Please Admit
Take the Poisons out of IT

Benedetta

cmo- I read that letter a while back - five plus or minus years. But 25 years ago I wrote my children's pedsssss (it was a group)

I wrote facts, reactions, what happened that one night - to convince them of what happened.

My children's peds I kept them -- till both of my kids were well into their teens -- and I pointed out things to me -- more importantly -- they pointed out things to me --that is they hinted at things I did not know that was linked to vaccines.

So in this letter it generously says -- You did not know.

That is not true. It is really really bad --. What would I do if I had put all this energy to be a doc and then specilized to be a ped -- had set up an office -- and was pulling in 1000s of dollars a month from the community -- I don't know if I would be brave as Wakefield, But I sure would not be as heartless as my children's peds either.

cmo

sometimes it it pretty obvious the other side is losing....

Dear Doctor: A Letter to My Child’s First Pediatrician

http://www.livingwhole.org/dear-doctor-a-letter-to-my-childs-first-pediatrician/?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+Livingwholeorg+%28LivingWhole.Org%29

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