Acne is a Disease: Don't Worry A Vaccine is Under Development
"This opportunity could provide an immunotherapeutic product with significant benefits and a novel mechanism of action to address an unmet medical need," according to Elias Zerhouni, M.D., President, Global Research & Development, Sanofi. "This investigational vaccine and treatment may lead to a better solution for the many who suffer from this skin disease."
According to Sanofi Pasteur's estimates, the annual worldwide market for acne therapeutics is in excess of US $3 billion. The financial terms of the agreement were not disclosed. The agreement includes a two-year research collaboration with Dr. Chun-Ming Huang and his associates at UC San Diego School of Medicine for further research and development.
About Acne5,6,7
Acne is an extremely common multi-factorial skin disease with a prevalence of 80 to 90 percent in adolescents. The disease sometimes continues through the teenage years; eight percent of 25 to
34-year olds and three percent of 35 to 44-year-old people continue to suffer from the disease. Moderate to severe acne occurs in 14 percent of five to 17-year olds and this group is more likely to seek treatment and currently faces an unmet medical need. Acne is considered a chronic disease for a limited life-time period and, although often a simple and self-limited condition, it can result in psychological, physical and social implications.
About Sanofi
Sanofi, a global and diversified healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients' needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, rare diseases, consumer healthcare, emerging markets and animal health. Sanofi is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY).
Sanofi Pasteur, the vaccines division of Sanofi, provides more than 1 billion doses of vaccine each year, making it possible to immunize more than 500 million people across the globe. A world leader in the vaccine industry, Sanofi Pasteur offers the broadest range of vaccines protecting against 20 infectious diseases. The company's heritage, to create vaccines that protect life, dates back more than a century. Sanofi Pasteur is the largest company entirely dedicated to vaccines. Every day, the company invests more than EUR 1 million in research and development. For more information, please visit: www.sanofipasteur.com or www.sanofipasteur.us
Forward Looking Statements
This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future performance. Forward-looking statements are generally identified by the words "expects", "anticipates", "believes", "intends", "estimates", "plans" and similar expressions. Although Sanofi's management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, including post marketing, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug, device or biological application that may be filed for any such product candidates as well as their decisions regarding labeling and other matters that could affect the availability or commercial potential of such products candidates, the absence of guarantee that the products candidates if approved will be commercially successful, the future approval and commercial success of therapeutic alternatives, the Group's ability to benefit from external growth opportunities as well as those discussed or identified in the public filings with the SEC and the AMF made by Sanofi, including those listed under "Risk Factors" and "Cautionary Statement Regarding Forward-Looking Statements" in Sanofi's annual report on Form 20-F for the year ended December 31, 2010. Other than as required by applicable law, Sanofi does not undertake any obligation to update or revise any forward-looking information or statements.
Read more: Sanofi Pasteur Acquires Exclusive, Worldwide License for Acne Vaccine and Treatment- The pre-clinical vaccine was developed by r - FierceBiotech http://www.fiercebiotech.com/press-releases/sanofi-pasteur-acquires-exclusive-worldwide-license-acne-vaccine-and-treatm#ixzz1ZTnX3aen
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Wow, I can't believe that, even a little sing can cause acne problem, thank for letting me this useful lesson.
Posted by: Meyly | July 08, 2016 at 12:03 PM
Theresa, thanks for the info about the buffering lotion. I too have cystic acne and am always looking for something that may help. I had about the worst case of teenage acne you could get in middle school and all the way through high school, and I now can't wear anything polyester. At least I no longer get it on the face--well, rarely.
Without a doubt over-consumption of sugars, HFCS, etc. is a major contributing factor. Just look at school lunches in your average public school. Access to vending machines in schools also doesn't help. Why wait in line and be forced to gobble down your food in 5 minutes for a 20 minute lunch break when you can just get some chips or a honey bun and a soda?
Posted by: Josh Day | October 03, 2011 at 01:55 PM
I saw a disgusting yellow ballon advertising a shingles vaccine in the grocery store today. A few steps away was a flu vaccine poster. Prepare for this while you're shopping:
http://3.bp.blogspot.com/-5MmgcgHxzGs/TjBXeGweQoI/AAAAAAAAAr4/GZVy0BZtGME/s1600/Shingles+Shot+006.jpg
Posted by: Stop Big Harma | October 02, 2011 at 05:18 PM
Well, Jeff, there's this:
http://www.msnbc.msn.com/id/30143726/
"But dermatologists say the bacteria that causes acne is increasingly developing resistance to some commonly prescribed antibiotics, including tetracycline and erythromycin. And while the superbug MRSA is a widely known threat in the general medical community, some patients are surprised to learn that the P. acnes bacterium is equally capable of rebelling against drugs and developing superpowers. It’s acne gone wild."
I also think the modern diet (lots of processed foods and sugar) is having an effect. This is purely anecdotal, but: my mom said a friend of hers (back in the 1960s) was put on a very restricted diet to lose weight, and at the same time, her skin became amazingly clear. Sugar feeds bacteria, right?
It's probably a lot of things, but you're right: I never see daguerrotypes of kids with acne.
As for not caring about death as a side effect of an acne vaccine... I can only say that I hope "l" is either faking, or finds some hope. Life is long; acne doesn't last forever. Anyone who doesn't like you based on your skin is a friend you don't need. I've been there. Hang in there.
Posted by: Theresa O | October 02, 2011 at 09:37 AM
Just wondering, but is acne another one of these modern plagues that was rare before the 20th century like autism, ADHD, asthma, peanut-caused anaphalaxis and allergies?
In those 19th century photos of pioneer families with twelve kids, I don't ever remember seeing one with pimples. Is acne relatively new?
Posted by: Jeff C | October 01, 2011 at 10:25 PM
I (?) wrote: "..I really don't care if a side effect to the acne vaccine is death, I would still get it in a heartbeat. I would rather die than have to live with acne anymore. acne has already completely ruined my life.."
**********************
Looks like we've drawn out at least one troll today. You're braking my heat... I.
Posted by: Barry | October 01, 2011 at 08:32 PM
To be serious, the problem with a vaccine for a bacterium is that we could see the same problem we've seen with Prevnar. The idea of an ever-escalating war on acne with new vaccines for new serotypes... it sends chills down my spine.
I hadn't heard of the mercury connection, Jeannette, but it wouldn't surprise me.
The one product I've used with great success (for cystic acne) is Buffering Lotion from Mario Badescu, which contains hydrolyzed yeast protein--my guess was that the yeast defeats the bacterium the same way Saccharomyces Boulardii can fight C diff ... but of course I actually have no idea. I just know that it worked for me when nothing else did, and it was topical, not systemic.
Posted by: Theresa O | October 01, 2011 at 08:13 PM
typo: death knell
I could add, never mind any evidence of neurological damage, severe brain fog, lack of mental focus, IQ loss, etc. from Hg exposure.
Posted by: Jeannette Bishop | October 01, 2011 at 07:21 PM
There is a lot of anecdotal information on the internet linking Hg exposure to severe acne. A long time ago I heard a dermatologist talk about how the only research that had found any link between any substance and acne was on fish consumption and now I tend to think of methylmercury perhaps? I can't help thinking that some really good research that found even a 2% link between amalgam and acne for instance could very easily be the dell knell of "medicinal" use of Hg.
So, are they going to preserve this "acne vaccine" with thimerosal?
Posted by: Jeannette Bishop | October 01, 2011 at 07:16 PM
I really don't care if a side effect to the acne vaccine is death, I would still get it in a heartbeat. I would rather die than have to live with acne anymore. acne has already completely ruined my life
Posted by: l | October 01, 2011 at 06:18 PM
Jeff C, you made my day. Yes, acne prevents both teen pregnancy and underage drinking (not invited to parties where it takes place--again, personal experience).
Posted by: Theresa O | October 01, 2011 at 03:50 PM
Barry - You forgot the part about lobbying states for acne vaccine mandates. Something like this... acne causes kids to get depressed... being around depressed kids causes their friends to feel sad (it's contagious!)... a depressed kid can become unstable (dangerous complications!)... and may even require hospitalization (very costly, vaccine is much cheaper!)
However, acne is very effective in preventing teen pregnancy (personal experience), so vaccinating it out of existence may have some unforeseen social costs.
Posted by: Jeff C | October 01, 2011 at 02:06 PM
... just in case anyone wasn't already convinced that vaccines are dangerous and completely ineffective medications. This is an embarrassment to anything that even resembles science.
And I can see it now, when this vaccine does absolutely nothing to prevent acne of any form. They'll say they didn't realize that booster shots were required for complete protection against acne. And then when 2, 3 or even 4 booster shots also make no difference at all, they'll still stand by their impeccable "science" on the matter... and claim it was genetics that caused all those vaccines to fail.
They'll walk away with their billions, and claim 'coincidence" for all deaths and injuries that were sustained along the way.
Posted by: Barry | October 01, 2011 at 01:01 PM