Educating Arne and ARRA
H1N1 Meeting Live Today

MMR: Overview of the Studies

Question mark

By Julie Obradovic
 
You know, I was wondering. Is the rate of pizza consumption in Chicago related to the rate of obesity in Boston?
 
Or, just what is the likelihood of being diagnosed with obesity in a hospital within 3 month intervals over several years after eating pizza in Finland back in the early 1980's?
 
Or, how likely is it that I will have evidence in my gut of having eaten pizza that made me sick 12 years ago, but not by actually looking at my gut?
 
Or, in Japan, when nobody ate pizza with sausage, pepperoni, and mushrooms for a little while, but still ate pizza with either sausage or mushrooms, any chance the obesity rate dropped?
 
Or, what about the chance that if we looked at a whole bunch of people in the US who ate pizza that all gained weight afterwards, the pizza had something to do with it if only a significant amount of them developed obesity?
 
Or how about the likelihood that if you eat this pizza in the UK before you gain weight the higher the rate of obesity?
 
And finally, among those same people in the UK who eat this pizza, any evidence they are thin, then gain weight and then develop obesity in that order? And if a significant number of them don't, like say they were already gaining weight when they ate the pizza, nobody became obese from the pizza?
 
Oh, I'll stop. I'm just being silly. A little humor to introduce a really not so funny topic. And now I'm hungry.
 
What has been studied about the MMR?

Although I will go into detail about the actual MMR studies shortly, I think the above analogies make it pretty easy if you just do the following. Everywhere you see these words, make these substitutions: eat= get; pizza = MMR vaccine; gain weight=develop bowel problems; obesity = Autism. If you do that, you now have a summary of the studies that have been done on the role of the MMR in Autism that supposedly prove it is not causal for anyone.
 
Again, I do not attempt to take this issue lightly by comparing it to pizza consumption and I'm not suggesting it's the perfect analogy. I simply want to point out the insufficiency of the studies that have been done thus far. They are a blatant example of how the MMR hypothesis is being fundamentally misinterpreted; the underlying assumption that if the MMR is causing Autism, it is causing Autism in everyone who has Autism, or paradoxically, that it would cause Autism in everyone who got the MMR. Based on these assumptions, researchers assume it should be picked up epidemiologically and more important, that if it's not, the MMR is exonerated of causing harm.
 
This is a wrong assumption and the reason the studies are inadequate for our children.
 
In science, you can do a study that is methodically perfect, every "t" crossed and "i" dotted. The researchers can be of the utmost integrity with impeccable credentials. But unless the question you are trying to answer is appropriate for what you studying, it doesn't matter. None of these studies ask the right question, even though many of their results show us the right answers.
 
So What Is the Right Question?
 
It is no secret that among those of us with children with Autism, we have different stories relating to the impact of the MMR on our children's disease. For some of us, its impact was obvious. Within weeks, days and sometimes hours there was a dramatic shift in our children's health. Seizures, diarrhea, high pitched screaming, fever, loss of skills and other signs of distress manifested quickly.
 
But for some of us, the impact was hardly noticeable if at all; it was quite some time before we recognized the damage retrospectively. For others, it doesn't appear to have had anything to do with their Autism what-so-ever.
 
Does that mean the role of the MMR can be dismissed entirely because we experienced different things? Of course not. As has been postulated for years, there may be many paths towards the same end result.
 
Among the many hypotheses of how the MMR and other vaccines may play a role are:
 
Susceptible children are first being assaulted with toxins that are known to damage the immune system and mitochondria leaving them vulnerable to a reaction from the MMR and/or the many other vaccines usually given simultaneously at that visit.
 
Or because the MMR is towards the end of a very aggressive vaccination schedule, it is the proverbial "nail in the coffin" for a child with a vulnerable immune system.
 
Or perhaps there is a specific genetic vulnerability to the measles virus or its vaccine components that causes an autoimmune reaction.
 
Maybe a history of antibiotic use coupled with other gastrointestinal distress that damages the gut flora has something to do with it.
 
Maybe because it's a triple live virus given simultaneously with the DTaP vaccine that contains aluminum and thimerosal there is a synergistic reaction between the metals and viruses.
 
Maybe it's all of this. Maybe it's none of this.
 
These are all questions that we don't have all of the answers to, and certainly there are more. We have no idea why only some children are reacting to the MMR vaccination visit, but that does not mean they aren't. So the question should be, why are certain children reacting to the MMR vaccination visit (or any vaccination visit for that matter) resulting in or exacerbating developmental regression and/or gastrointestinal distress, and are the two related?
 
This is a substantially different question than the only studied question, "Are children reacting to only the MMR in this way based on a comparison to children who did not?"; the equivalent of studying hundreds of thousands of children who eat peanuts and then publishing that because an insignificant amount of them went in to anaphylatic shock, peanuts aren't causal. You have to dig deeper than epidemiology when correlation and causation aren't obvious through it, not stop looking. It's the first step, not the only step.
 
In fact, several of the studies I will discuss do provide evidence of small groups of children who are affected by the MMR in precisely the way they are trying to rule out, and strangely, the authors repeatedly acknowledge this.
 
Which leads me to study #1. (Remember, the studies are being presented in the order in which they appear on the Fourteen Studies website and that M1 represents MMR study #1, etc.)
 
The Studies, General Concerns
 
There have been 8 major studies completed on the role of the MMR in Autism. Of the 8 studies, 4 of them were completed by a vaccine patent holder and/or expert witness for the government in MMR litigation (M 2,3,4, 6). One study did show that the MMR may be associated with Autism when the data was reanalyzed (M5), and only one study (M1) used children from the United States (significant because US children are more vaccinated than any other). This study found that indeed 20% of the study participants did regress into Autism in this order: MMR-GI disturbance-Autism diagnosis.
 
No study compared children who received the MMR to those who have never been vaccinated at all, and even in one that compared children who got the MMR to those who didn't (M5), those who didn't, did in fact receive the Measles and Rubella vaccines. And finally, no study looked at the children who were affected by the MMR immediately following their reaction to it to look for evidence of a problem.
 
The Studies, Specific Concerns
 
1.  Lack of Association between Measles Virus Vaccine and Autism with Enteropathy: A Case-Control Study (Hornig, et.al 2008)
 
Question Asked: Do 25 children in the US with Autism have a persistent measles virus RNA in their GI tract that they got from their MMR vaccine that 13 other children with GI disturbances but not Autism don't have? And in those 25 children with Autism is there a temporal relationship between MMR vaccination, GI episodes, and Autism onset?
 
Published Conclusion: No. There is not a significant amount of children with Autism that either had Measles RNA in their guts compared to the children without Autism, or that regressed in the order of MMR, GI stress, and Autism.
 
Conflicts: CDC and AAP participation; 2 authors were compensated for expert witness statements regarding MMR in UK litigation.
 
Problems:

• This study looks exclusively at kids who have GI problems, 25 with Autism and 13 without Autism, hardly a large sample size of kids to look for such a specific pathology. Still, 52% of the chlidren with Autism did indeed regress after the MMR, and 52% of all of the children did indeed experience their GI problems after the MMR. 20% of the children with Autism did regress into Autism in this order: MMR, GI problems, and then Autism. 1 child with Autism did have Measles virus RNA in his small and large intestinal biopsies, replicating Wakefield's findings. Additionally, 64% of the children with Autism had evidence of GI disturbances prior to the MMR. This fits the hypothesis that they are already susceptible to reacting to the MMR, which we know can cause further damage to the gut and is home to much of the immune system. It is entirely plausible that the MMR can exacerbate existing problems. Finally, this study took place years after the MMR vaccination was given, making it plausible the virus cleared before the biopsy but left behind damage.

Actual Conclusion:  This study shows that even among 25 kids with Autism, 5 of them regressed into Autism in the order of MMR-GI problems-Autism and 1 of them still had Measles RNA in their guts years later. So YES, for some children the MMR is an issue.
 
2. MMR Vaccination and Pervasive Developmental Disorders: A Case-Control Study (Smeeth, 2004)
 
Question Asked:  Do children in the UK who got MMR vaccine before Autism diagnosis have higher rates of Autism?
 
Published Conclusion: No.
 
Conflicts: An author is an expert witness for vaccine manufacturer and member of the Joint Committee on Vaccination and Immunization.
 
Problems:

• The authors were not able to separately identify the subgroup of cases with regressive symptoms to investigate the hypotheses that only some children are vulnerable to MMR induced disease, which is truly the point. Also, the odds ratio associated with MMR vaccination varied according to the age they entered the database used. Odds were higher for children who joined the database at birth or before their first birthday to be diagnosed with Autism after MMR.

Actual Conclusion: This study does nothing to identify subsets of chlidren of children susceptible to MMR-induced disease.
 
3.  Pervasive Developmental Disorders in Montreal, Quebec, Canada: Prevalence and Links with Immunizations (Fombonne 2006)
 
Question Asked: Are Thimerosal use and MMR uptake in Quebec City related to rates of Autism in Montreal?
 
Published Conclusion: No.
 
Conflicts: Lead author is expert in MMR litigation.
 
Problems:

• Study looked at MMR uptake in Quebec City and compared it to rates of Autism in Montreal. I'm serious. Moreover, thimerosal was not discontinued in Canada until 1996, and estimates are that it wasn't off the shelves until 1998, yet this study does not evaluate the health outcomes of children born after 1998. It does not include exposure to Thimerosal via Hep B shot, Flu Shots or Rhogam shots, and the actual exposure to Thimerosal the children studied received was estimated, not actual. No never-vaccinated children were studied.

Actual Conclusion:  Maybe the stupidest study done in the group. Worthless. Pointless. Sorry, just being honest.
 
4.  No Evidence for a New Variant of Measles-Mumps-Rubella Induced Autism (Fombonne, 2001)
 
Question Asked: Is there evidence in children in the UK between MMR vaccine and a form of Autism that is a combination of developmental regression and gastrointestinal symptoms that occur shortly after immunization?
 
Published Conclusion: No.
 
Conflicts of Interest: Fombonne again.
 
Problems:

• There are no biological investigations on the children in the study and instead survey responses are used. Compared 96 children diagnosed with PDD post MMR to 98 children diagnosed with Autism pre-MMR to 68 patients diagnosed with Autism post-MMR. No children without MMR and Autism or PDD were studied, and no children with a PDD diagnosis pre-MMR were used, imbalancing the study. Shockingly, no inflammatory bowel disorders were reported among any of the children surveyed. Finally, the author arbitrarily defines how the MMR must be involved in Autism if it is involved at all with no basis for his definition. He assumes that it must 1) be identified closer to immunzation than other Autisms 2) now be more common 3) have distinct symptoms and severity problems 4) is associated with gastrointestinal symptoms and/or imflammatory bowel disorder. No never-vaccinated children were studied.

Actual Conclusion: Did nothing to answer the question about a specific subset of children affected by MMR induced disease based on clinical and/or biological data.
 
5.  No Effect of MMR Withdrawal on the Incidence of Autism: A Total Population Study (Honda, 2005)
 
Question Asked:  Did MMR withdrawal in Japan in 1993 have an effect on incidence of Autism?
 
Published Conclusion: No, but admits, "Epidemiological data, however, cannot test the very different hypothesis that MMR might involve an increased risk of ASD in a very small number of children who, for some reason, are unusaually susceptible to damage from the vaccine." Well, no kidding.
 
Conflicts: None listed.
 
Problems:

• Study did not address the affected children. A recalculation of the data does show that the MMR does appear to have had an affect on Autism Spectrum Disorder rates. And finally, while children in the study were not vaccinated with MMR in 1994 and beyond for some time, children were still vaccinated against Measles and Rubella between 12 and 36 months; Mumps was optional for children on year or older. No never-vaccinated children were studied.
Actual Conclusion: Study tells us nothing about a subset of children who could be affected by MMR.
 
6.  Measles Vaccination and Antibody Response in Autism Spectrum Disorders (Baird, 2008)
 
Question Asked: Do children in the UK with Autism, special needs or normal development aged 10-12 years old have presence of measles virus in the bowel, but not by actually looking at the bowel? And is there a dose-response relationship between autism symptoms and antibody concentrations?
 
Published Conclusion: No.
 
Conflicts: Lead author is defendant's expert in UK MMR litigation; 2 others have given unpaid advice to lawyers in MMR litigation.
 
Problems:

• Claims using mucosal samples of children's guts is "unethical" (slam of Dr. Wakefield, no doubt) and therefore used "an appropriate proxy for gut mucosal cells" called peripheral blood mononuclear cells. In other words, they looked for measles virus in the gut without looking at the gut. Additionally, they admit the limitations of using a survey to elicit accurate reporting of gut symptoms, "...the children were too old for accurate reporting of retrospective gut symptoms confidently contemporaneous with MMR vaccination," which is kind of the point of the study, no? Finally, only vaccinated children were studied 9 years post MMR vaccination, and only 29% of the ASD kids had a second MMR compared to 50% of those who had no ASD diagnosis. This is significant for trying to find out if there is a dose related response by measuring titers.
Actual Conclusion:  Study fails to tell us anything about what happened to the affected children at time of exposure.
 
7.  Neurolgoic Disorders After Measles-Mumps-Rubella Vaccination (Makela 2002)
 
Question Asked:  Are neurological disorders associated with MMR uptake in Finland from 1982-1986 based on the likelihood of being hospitalized for Autism within 3 month intervals of receiving the MMR up until 1996?
 
Published Conclusion: No.
 
Conflicts:  Sponsored in part by a grant from Merck, makers of the MMR.
 
Problems:

• Oh, where to begin. Let's see...used kids in Finland...in 1982...that got hospitalized for Autism...within 3 month intervals following their MMR. Authors did not identify one child with Autism with an inflammatory bowel disorder and had no access to outpatient data. Study admits, "Reliable assessment of causality between immunization and rare disorders is extremely difficult...evidence of several of the suspected adverse effects of MMR vaccination has remained inconclusive....diagnosis of Autism does not always involve hospitalization...as the coverage of the MMR vaccination register was not complete, some children regarded as unvaccinated may have actually been immunized during the study period."

Actual Conclusion: Study tells us nothing about the affected children in a real world setting. The likelihood of being hospitalized for "Autism" is virtually non-existent. And none of the children "hospitalized" for Autism made visits because of inflammatory bowel diseases.
 
8. Association of Autistic Spectrum Disorder and the Measles, Mumps and Rubella Vaccine: A systematic Reveiew of Current Epidemiological Evidence (Wilson, 2003)
 
Question Asked: Do the previous studies as of 2003 support an association between MMR and Autism?
 
Published Conclusion: No.
 
Conflicts: Funded by a grant from Canadian Institutes for Health Research
 
Problems:

• This is simply a study of the other studies. It excluded the studies done examining only a link between the MMR and the GI tract, or between maternal MMR and then development of ASD (Wakefield and Yazbak). It concludes that, "...limited epidemiological evidence exists to rule out a link between a rare variant  form of ASD and the MMR vaccine", but still recommends maintaining our current MMR vaccination policy because the danger is theoretical only. Finally, it sites a study as evidence of MMR safety that finds no cases of ASD in 1.8 million individuals who received MMR. Exactly where are these people with no Autism among 1.8 million of them? FINLAND....which begs the question, how can that be? That study was done by the same author using the same data as study #7 which found 309 children hospitalized for Autism (out of 535,544 1-7 year olds vaccinated with MMR between 1982-1986) between 1982-1996, yet NONE in almost 2 million in another study using the same people in the same time period? And both studies are used as evidence for MMR safety?Hmmm....

The only conclusion we are left with after all of these studies is this:
 
The results are inconclusive at best, and as evidenced by the last study, being drawn from questionable data.
 
Even assuming it weren't, the only conclusion we can truly draw is that the MMR does not appear to be causally linked to Autism for the general population, but we still have no idea if it is causing Autism in a susceptible sub-group of children that could not be identified epidemiologically. Those are the words of the authors themselves.
 
So why they don't feel inclined to dig deeper and answer that question then is beyond me. No wait, it disgusts me. These are our children, and they deserve better. They deserve more research into this, not less. And damn it, they deserve it now.
 
How many more of them will be "theoretically" harmed before they get it?

Julie Obradovic is the mom of a recovered child. She is a member of NAA, a Rescue Angel, and a leader of the TACA Chicago Chapter and a Contributing Editor for Age of Autism.


 
 
 
 
 

Comments

Myra

Just looking at the articles, and pulled up the Fombonne one. I am from Montreal and Fombonne is quite famous here. You stated that the major flaw in this article is the fact that the question was: are Thimerosal use and MMR uptake in Quebec City related to rates of Autism in Montreal?, and that the uptake of inhabitants of Quebec city was measured against the incidences of autism in Montreal (a different city).

Reading the article this is what it said of the subjects:


"In the province of Quebec, children are educated either in English or French schools. Schools belong to school boards that are also organized according to language. The largest school board for Anglophone children in Quebec is the Lester B. Pearson School Board (LBPSB), which provides education to individuals in the south and western parts of the greater Montreal area. "

Therefore, all the subjects were from the province of Quebec, and uptake was measured in Quebec (the province) within which Montreal exists.

Just to try to clarify this point, so it is not seen as being such as massive flaw in the study.

kathleen

Craig, I saw that this morning, it's so very sad. I'm sure the "scientists" are hard at work to disprove the link instead of any due diligence to protect our children.

Cherry Sperlin Misra

Phyllis Lorenzo, Your cousin is absolutely correct. To know this one simply has to observe the behavior of the medical/pharma establishment of the past 10 years. Everything that happens in the field of vaccines and autism shows us the hand that confuses and distracts and delays. As in Sleeping Beauty- let 100 years pass- Mercury is out of dentistry, out of vaccines, out of the high fructose corn syrup, no one is eating mercury laden fish any longer /power plants are no longer burning coal and the story will be "My God, those crazy doctors of the 21st century- injecting mercury all over the place- even into pregnant women and tiny newborns! Its just incredible. What were they thinking? " ....Just look at the story which the hidden hand cooked up to fool the young pediatricians. When mercury was reduced and ear infections in babies dropped, they were told "Wow, look at this- It turns out our Prevnar vaccine is preventing ear infections! " ...and the young doctors fell for it. Who does this ? Who is the face connected to this hidden hand? I believe that our only chance to change the course of history in this regard is the internet.

Kathy Blanco

Well, I guess I am loony to think all parts of the vaccine are unsafe, and as stated by a lab person in vaccine industry, all vials are inheritedly unsafe and unstable. So, there goes the complicent "workable" parent in me. Again, I think some of you like vaccines, that's your right, but having an autism community complicent with these murderers, is making no sense, none, to me. The only thing they understand is if their safety bubble is breached by untrust, then you have a hell of a lot of mommies not getting their children vaccinated. And oh, that blessed day, if it will ever come? If anyone things vaccines work, tell me...show me the science that they do? Ok, then if you can't, then why are we liking them and for what reason?

Phyllis Lorenzo

I have a cousin in the medical profession who believes that the link between vaccines and autism will not be exposed until they have discretely replaced thimerosol, aluminum, and decreased the doses, etc, and there is no one in our lifetimes left to sue them. I hope she is wrong.

We need to all of us demand that the vaccine schedules be changed like other countries are doing while at the same time get to the bottom of any criminal activity that has been going on to hide or alter the truth. Our children's lives and our own lives are being destroyed potentially over their immoral desire to make huge profits.

Anyone who thinks that we're a bunch of looney parents who don't want to vaccinate our kids, think again. We just don't want avarice and the almighty dollar to play a part in the possible poisoning of our kids!!!

Gale

Thanks AoA as per usual Thanks. Gotta give a presentation, gotta know stuff, you gave me stuff. Important stuff about logic and life. Very clearly laid out and I need to read it again. Great work.

michael framson

Julie, all of your analysis should become a textbook. I'm not sure it would be used by those who are too indoctrinated, that they wouldn't be able to recognize a good analysis from the crap we've been conditioned to accept.

It seems pretty simple; if you don't want to know the truth, don't ask the right questions.

Rob

I find it interesting that in many US states, MMR is given at 18 months, and it is considered coincidental that children also regress at 18 months. However, where I reside, the MMR is given at 12 months, and my son, like most children with autism locally, regressed at 12 months, not 18. Hmmm...

Luke Tunyich

(Quote; Julie Obradovic)
“We have no idea why only some children are reacting to the MMR”

That is the crucial question that can be answered. On the other hand is the question “will it make any difference if this question get answer as long as the autism epidemic is denied by most of established medical professionals.

Medical establishment have no idea why only some children are affected with Type 1 Diabetes. Worldwide, the incidences of Type 1 Diabetes are increasing every year by 3-4%.
At the moment only some children are affected with Type 1 Diabetes. But how many years is left till every child will be affected with Type 1 Diabetes?

The crisis in medical science is bigger that everyone can imagine.

Medical science researches have no idea why some people can eat as much as they like and being inactive yet not become obese or even overweight.

For many years I have been pointing out that entire understanding of obesity is based on misconception.
People of all age are victim of the MEDICAL PSEUDOSCIENCE.

The epidemic of obesity unknown to any previous generation isn’t the fault of the people but is the fault of the medical science researchers of obesity, the public health agencies, and the medical practitioners. They don’t have an objective understanding of the phenomenon and they are reluctant to admit that till 2007their understanding about cause of obesity is formed without knowing that significant energy live body as metabolic waste.

From one side people affected with obesity are exploited by weight-loss industry and medical practitioners and from the other side they are patronised and ridiculed from the medical science researchers of obesity and the public health officials.

More about medical pseudoscience can be found on this links;
http://www.biomechanicsandhealth.com/calories.htm

http://www.biomechanicsandhealth.com/energybalance.htm

Sorry for long post that seems out of the topic but in my opinion it isn’t out of topic. As I said on beginning the crisis in medical science is bigger that most people can comprehend.

Cherry Sperlin Misra

The MMR still remains something of a puzzle for me and perhaps Julie can shed some light-Were all U.S. kids given MMR along with a Thimerosal containing vaccine? If so, why is the MMR blamed for autism.? Why not the mercury? I notice that many parents who blame the MMR for autism never give details about other vaccines given at the same time. In India the schedule of the private pediatricians shows the MMR being given along with or close to 2 mercury vaccines. I think this is just nuts. How can you give three live viruses at the same time as two vaccines that damage the immune system? It just boggles the mind that senior pediatricians, often educated in UK or the US (after doing their basic medicine in Indian) set vaccine schedules that show no awareness of research of the last 10 years. But back to my first question- I'd love to know about the situation in the U.S. and if anyone knows of cases where a child became autistic after an MMR given alone.

Teresa Conrick

Great summary, Julie. Epi studies are not always helpful and are usually very harmful especially when the conclusion has been decided prior to the hypothesis or the gathering of data.

It appears industry, politics and an archaic public health system have morphed into a "program" which substitutes health and welfare with profit and power.

Jake Crosby

I'm surprised the Brent Taylor study was not among those critiqued. Also, wasn't there another failed MMR study done in Denmark, and another done by the CDC lead by Frank DeStefano?

Craig Willoughby

Hey guys, slightly off topic, but still important.

British girl dies after cervical cancer vaccine.
http://www.msnbc.msn.com/id/33070294/ns/health-kids_and_parenting/

Chris Cordes

Steve, My pizza is just as much a pizza as your pizza. :)

steve

Julie said "Don't you love how the conclusion is announced right in the title of some, for the benefit of the lazy?"

Actually it is scientific etiquette to put as much information in the title as possible. The title of a journal article is not the same as the title of a magazine article, the point isn't to be clever, it's to be informative.

I would like to know the opinion of the main author about this study here.
http://www.ncbi.nlm.nih.gov/pubmed/16865547?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

MMR-vaccine and regression in autism spectrum disorders: negative results presented from Japan.
Uchiyama T, Kurosawa M, Inaba Y.

Department of Human Welfare, Otsuma Women's University, 2-7-1, Karakida, Tama-city, Tokyo, 206-8540, Japan. tokiouch@otsuma.ac.jp

It has been suggested that the measles, mumps, and rubella vaccine (MMR) is a cause of regressive autism. As MMR was used in Japan only between 1989 and 1993, this time period affords a natural experiment to examine this hypothesis. Data on 904 patients with autism spectrum disorders (ASD) were analyzed. During the period of MMR usage no significant difference was found in the incidence of regression between MMR-vaccinated children and non-vaccinated children. Among the proportion and incidence of regression across the three MMR-program-related periods (before, during and after MMR usage), no significant difference was found between those who had received MMR and those who had not. Moreover, the incidence of regression did not change significantly across the three periods.

Kent Heckenlively

Julie:

Thanks for doing a wonderful job summarizing the MMR issue. I hope articles like yours get wide distribution.

All the best,
Kent Heckenlively

John Stone

Great article Julie. Supplementary to it I give a run down of Cochrane's conclusions about the six best MMR/autism studies, as of the end of 2004 in this post to BMJ Rapid Responses:

http://www.bmj.com/cgi/eletters/339/sep09_1/b3658#220537

With regard to the Honda paper no one should miss Clifford Miller,'Japanese data show vaccines cause autism':

http://childhealthsafety.wordpress.com/2009/06/03/japvaxautism/

Steve

Unfortunately thanks to the MMR some people can only eat GFCF pizza, which really isn't a pizza.

julie

Thank you Julie for pointing out that these studies are strictly amateur hour. A 7th grader could design better studies. Don't you love how the conclusion is announced right in the title of some, for the benefit of the lazy?

A lot of these authors seem to work as expert witnesses. Do you think if we called the GMC they would be subject to a 4 year long hearing?

Theresa

Wow, Julie, that is really good work! Thank you for reading all those studies and explaining them so succinctly. I'm looking forward to your next piece. Maybe we can all send this to our legislators if Carolyn Maloney's vaccinated/unvaccinated bill ever comes up for a vote again.

Kevin

LOVED this quote:
"the underlying assumption that if the MMR is causing Autism, it is causing Autism in everyone who has Autism, or paradoxically, that it would cause Autism in everyone who got the MMR."

Thanks Julie, great summary of the crap their dishing out. Now if someone could just get through to my family whom two are pregnant...

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