Struggling to Communicate: Autism and the Media
National Autism Association on IACC Removal of Vaccine Safety Research

Alison Singer Feeds the Hungry Lie – Twice

2 pigs By J.B. Handley
I thought I'd seen everything.
I work in corporate America, and I have never before seen an employee with a managed termination (a nice word for getting fired) issue their own press release announcing their "resignation" from a job, five minutes before their employer does the same thing.
And yet, that's what Alison Singer did – she issued her own press release announcing her termination (in so many words). Go figure.

Worse, Ms. Singer characterized her separation from Autism Speaks as a philosophical disagreement on the issue of vaccines and autism. Doesn't she realize she effectively is saying, "The rest of the largest autism organization in the world feels one way, but I, singularly, feel differently"?
So, thank you for that--you certainly help make our case.
And, as if on cue, Ms. Singer, in her own press release, feeds the ever-hungrier lie when she writes:
"Dozens of credible scientific studies have exonerated vaccines as a cause of autism."
Alison, if you haven't read my post, FEEDING A HUNGRY LIE, now would be a good time to do it before you go and talk to…Newsweek?
Yup, Ms. Singer has already found her way into Newsweek, at least the online edition. In seeing what she had to say, it struck me that maybe she had read my post, and just chose to lie anyway. How else to explain this nearly unbelievable quote:
"There are more than a dozen studies that show no causal link between the MMR [measles-mumps-rubella] vaccine and autism, and thimerosal [a mercury-containing vaccine preservative] and autism. Over and over, the science has shown no causal link between vaccines and autism."
Amazing. We looked at MMR, we looked at one ingredient, we compared vaccinated kids to vaccinated kids, never considered the other 11 vaccines on the schedule, time to move on.
To backtrack for a moment, Every Child By Two ran Ms. Singer's personal press release announcing her termination. A nonprofit funded by a vaccine company (with Paul Offit on their board) runs a press release about a leader of an autism organization being fired? That's just weird.
Perhaps weirder is this email I got from a super mom today, she writes:
"I knew that title sounded familiar. Say hello to Alison's new partner in crime, as if we didn't know already. 
From Newsweek: 'This Question has been Asked and Answered'

Alison Singer: At some point, you have to say, "This question has been asked and answered and it's time to move on." We need to be able to say, "Yes, we are now satisfied that the earth is round."
From NY Times, AP, Reuters June 12, 2007:
"From my standpoint, this question has been asked and answered," Dr Paul Offit, of the Philadelphia Children's Hospital, who helped invent a rotavirus vaccine, told reporters. 
From CNN April 2, 2008: Vaccine-autism question divides parents, scientists.
Paul Offit: "It's been asked and answered: Vaccines don't cause autism," Offit says.
The hungry lie lives. Alison Singer, the mother of a child with autism, tells it shamelessly. This same mother has ECBT, a nonprofit funded by Wyeth, issue her press release announcing her termination. And, this same Mom parrots Paul Offit in her interviews.
Did Autism Speaks do the right thing? The question has been asked and answered: Hell, yes!!

J.B. Handley is co-founder of Generation Rescue and a contributor to Age of Autism.


Dissertation UK

The article is really nice, but we have to think how we can solve this problem for elementary schools. Thanks for such a nice post.

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Wonderful article, thanks for putting this together! "This is obviously one great post. Thanks for the valuable information and insights you have so provided here. Keep it up!"


i second that "hell yes!"
i can feel our day is coming. i can feel it!


Beth Feldman wrote an article about Alison Tepper Singer for The Huffington Post back in 2006:

"Mom of Reinvention: Alison Singer"

Here's a quote from near the end of that article:
Alison continues to work a flexible schedule in order to accommodate the needs of both of her children and when asked if she'd ever consider eventually moving back into the corporate world, she says her answer is simple. "I am planning to stay at Autism Speaks until the day we find a cure."
Perhaps now that she's GONE, Autism Speaks can start funding studies which may get closer to finding the cause(s) of autism,as well as hopefully, the "cure(s)".

Robin Nemeth

I have this bumper sticker on my car. Actually I have two of them. One says ‘CDC poisons children’ and has a clipart picture of a syringe. The one on the other side of my bumper has a picture of a pea pod, and it says ‘Autism Speaks and pharma-peas in a toxic pod.’

When I read that Alison had resigned from Autism Speaks, I was inclined to think about taking the pea pod bumper sticker off. I wasn’t sure if I should, but I went outside and picked around the edges of it. Unfortunately what I found is that in minus zero degree weather, bumper stickers come off of your car in little itsy bitsy brittle flakes, if at all.

I remember a few years ago, when I still had the Wall Street Journal delivered, seeing a story on the front page in which Alison Singer was quoted as saying something to the effect of “the only thing that parents of children with autism do wrong is they have bad genes.” There was quite an outcry from the autism=vaccine damage community, and an apology was issued by Ms. Singer. It wasn’t posted though on the front page of the WSJ, it was a one sentence apology on the AS website, and I don’t know how long it was up but when I looked again a week or two later it was all gone.

What matters to me most isn’t what Autism Speaks says on their website. They take in more money, I believe, for autism, than any other autism charity organization. What do they do with that money? What is the public face of AS? I don’t believe their website is the whole story, or even a large part of the story.

I’ve seen Autism Speaks spots on my cable channels, many of them, in recent months. I suppose they’d be called public service announcements. Yes, they’re publicly doing a grand job of raising awareness. But there is STILL never any mention of vaccines, or even of environmental damage.

So AS, as an organization, is claiming now, on their site, that they’ve gotten with the program, they’ve seen the light. They know, now, that autism is environmental and that it’s probably vaccines and that we’ve been right all along and it should be looked into. But the thing that still has me bothered is this—they are saying this to us. And that’s good. But they’re preaching to choir. Imagine the good that could have been done if they’d taken their dollars and, in the last few years, said the same things to the PUBLIC.

It’s hard for me to imagine that in the last year, Alison’s views have been unknown by those around her, and vice versa. JenB asked “was it AS’s intent to say one thing and act another?” It looks to me like it was.

I can’t fathom why she’s come out publicly with her views right now. I can’t fathom why she’s split with Autism Speaks, although somewhat less publicly, now. I know it’s no coincidence, but I don’t quite know what it means.

Look at what we’ve seen in the main stream media in recent weeks. Newsweek, Discover Magazine, ABC Private Practice’s ‘Contamination’ episode. Basically it’s been the SOS we’ve seen all along. Perhaps even a bit worse.

IE. .. ‘Alison singer—autism hero’. Omg. Somebody pinch me and wake me up.

I can’t help but wonder if some of the money to pay for some of this type of main steam media coverage has come from AS.

Anyway, I’m thinking it might just be fortuitious that my bumper sticker is adamantly opposed to coming off just yet.

Time will tell.


What about all the birth control pills women have injested for years before they decided it was the right time to have a baby. What about all the abortions women had because it wasn't the right time for them to have children. What about all the
Amos tests they had to see if everything was okay and if it wasn't they would abort.
All these things had to have an effect on
their bodies.


What's the evidence that she was fired and who is your source for this information?


If Singer wants genes, why doesn't she try these on for size-

Possible immunogenetic basis for autism
Roger A. Burger *, Reed P. Warren
Utah State University, Logan, Utah
email: Roger A. Burger (

*Correspondence to Roger A. Burger, Utah State University, Logan, UT 84322-6895

Autism results from several different etiologies or combination of pathological mechanisms. Mounting evidence indicates that immune dysfunction along with an environmental pathogen may be factors contributing to the development of some cases of autism. One of the immune deficiencies observed in autism is abnormal T-cell mediated immunity. Another is altered levels of certain classes of antibodies (immunoglobulins), including decreased levels of immunoglobulin A and deficient complement activity, based on the inheritance of a null allele of the C4B gene. In addition to the C4B gene, other genes on chromosome 6 also appear to be associated with autism. In the developing child, genetically determined immune deficiencies might increase the risk for autism in two ways: 1) A pathogen or its toxins might damage the brain, 2) the pathogen might trigger an autoimmune mechanism that would interfere with brain functioning. In the mother, immune deficiency might allow a pathogen to persist in utero, damaging the fetal brain directly or triggering a maternal immune response that creates pathogenesis in the fetal brain.


Significant association of HLA A2-DR11 with CD4 naive decrease in autistic children.
Ferrante P, Saresella M, Guerini FR, Marzorati M, Musetti MC, Cazzullo AG.

Laboratory of Biology, Don C. Gnocchi Foundation, IRCCS, via Capecelatro 66, 20148 Milan, Italy.

Nine autistic children and 37 ethnically homogenous controls were enrolled in the study to assess their human leukocyte antigen (HLA) pattern, and eight healthy children were studied to define their peripheral blood cell subsets. We observed a significant decrease in CD4+ naive and an increase in CD4+ memory T cells in autistic children. These differences were significantly more pronounced in the autistic children bearing the HLA A2 and DR11 alleles. These data support the hypothesis that autism could be due to an immune imbalance occurring in genetically predisposed children.

Confirmation of the association of the C4B null allelle in autism.

Odell D, Maciulis A, Cutler A, Warren L, McMahon WM, Coon H, Stubbs G, Henley K, Torres A.

Center for Persons with Disabilities, Utah State University, Logan, UT 84322, USA.

The objective of this study was to examine and attempt to confirm our previous findings of an increased frequency of the C4B null allele (C4BQ0) in subjects with autism. Newly identified subjects from Utah and Oregon were studied. Families evaluated included 85 who had a child with autism and 69 control families. Of the subjects with autism studied, 42.4% carried at least one C4BQ0, compared with 14.5% of the control subjects (p = 0.00013), with a relative risk of 4.33. Over half of the C4B null alleles in the subjects with autism involved C4A duplications. A marked increase in the ancestral haplotype 44.1 that lacks a C4B gene and has 2 C4A genes was also observed. The results of this study suggest that the human leukocyte antigen class III C4BQ0 significantly increases the risk for autism.


Yet live virus vaccines, for which immunodeficiency is a contraindicated condition, have nothing to do with autism.
Bullshit Alison, you smell like Offits bunghole- had your nose there lately?

I am betting she is already cozied up with ECBT.

How fucking long can this lie live?


Got any room at that toilet bowl? I'm sickened by this. These people are, I can't put it into words because monster, Hitler, disgusting...just aren't strong enough words.

Kathy Blanco

Other than Fragile X, which I think is an iron disorder in generations, autism is NOT genetic. I say this, because like familial tendency to not handling metals, or infections, or other oxidative stresors runs in families. I have seen personally in my family, many spectrums of autism, however, the biochemistry is similar, they all have high metals, they have infections (lyme), they have no ability to handle oxidative stress. SO WHAT IS GENETIC REALLY?

I would like to have prenatal testing in one light, and that is, to identify mothers with Low Cholesterol, (this is important in autism), High Testosterone (this is also important), mercury loads, infections of all types, thyorid diseases, if she has autoimmune diseases, and then TREAT her, during her pregnancy with IV Glutathione's/Zincs, balancing biochemistry, treating thyroid, so you basically change the biochemistry of how genes express, and then the autism so called is not expressed because the body was allowed to heal before even born. Most moms of kids with autism have glutathione block/metabolic problems/thyroid dysfunctions and infections and toxins galore. Let's think about what protocols could be used to save lives, not diminish them.


I just read Katie Wright's comments to the Newsweek story and I have to say that I am very distressed to learn that, apparently, Singer sabatoged funding for families whose childrens' ASD was not genetic, because her family's ASD is? I feel for the 1-5% whose are purely genetic, but what about the rest of us 95-99% whose ASD is laboratory proven NOT genetic?

This explains A LOT, not the least of which is the crap that was the AS message boards.

I have to go throw up now.




Hogwash SS.

When a human being is injected with toxins in vaccines, when pregnant women and babies and childred are injected with toxins in vaccines, very bad things happen. It's NOT a coincidence. It is not complicated. It is cause and effect. It is in the toxins' material safety data sheets.

0.5 parts per billion (ppb) mercury = Kills human neuroblastoma cells (Parran et al., Toxicol Sci 2005; 86: 132-140).

2 ppb mercury = U.S. EPA limit for drinking water

20 ppb mercury = Neurite membrane structure destroyed (Leong et al., Neuroreport 2001; 12: 733-37).

200 ppb mercury = level in liquid the EPA classifies as hazardous waste.

25,000 ppb mercury = Concentration of mercury in the Hepatitis B vaccine, administered at birth in the U.S., from 1990-2001.

50,000 ppb Mercury = Concentration of mercury in multi-dose DTaP and Haemophilus B vaccine vials, administered 4 times each in the 1990's to children at 2, 4, 6, 12 and 18 months of age. Current "preservative" level mercury in multi-dose flu (94% of supply), meningococcal and tetanus (7 and older) vaccines. This can be confirmed by simply analyzing the multi- dose vials.

THIMEROSAL Hazard symbol: T+ = Very toxic
Criteria: Inhalation, swallowing, or absorption through the skin in very small amounts can cause considerable damage to health, and may sometimes be lethal. In the event of serious evidence of severe, possibly irreversible damage to health by single, repeated, or prolonged absorption. Precaution: All contact with the human body must be avoided. If you feel unwell, seek medical advice immediately!

Symptoms of exposure to this class of compounds includes aphthous stomatitis, catarrhal gingivitis, nausea, liquid stools, pain, liver dis- order, injury to the cardiovascular system and hematopoietic system, deafness and ataxia. Exposure may be fatal. Headache, paresthesia of the tongue, lips, fingers and toes, other non-specific dysfunctions, metallic taste, slight gastrointestinal disturbances, excessive flatus and diarrhea may occur. Acute poisoning may cause gastrointestinal irritation and renal failure. Early signs of severe poisoning include fine tremors of extended hands, loss of side vision, slight loss of coordination in the eyes, speech, writing and gait, inability to stand or carry out voluntary movements, occasional muscle atrophy and flexure contractures, generalized myoclonic movements, difficulty under- standing ordinary speech, irritability and bad temper progressing to mania, stupor, coma, mental retardation in children, skin irritation, blisters and dermatitis [173]. Other symptoms include chorea, athetosis, tremors, convul- sions, pain and numbness in the extremities, nephritis, salivation, loosening of the teeth, blue line on the gums, anxiety, mental depression, insomnia, hallucinations and central nervous system effects [301]. Exposure may also cause irritation of the eyes, mucous membranes and upper respiratory tract [269].


WOW, Kim.
Your answer to Christina just floored me. I guess I never put all the dots together until you worded it that way. I honestly have the urge to cry. If this goes through and it works out the way that Singer wants it too. God help us all. It has been my experience (with some, not all) that doctors already have a God complex, Singer is handing them their lightning rod to strike down innocent babies.
In each one of my pregnancies I was offered an amnio. I refused everytime. I didn't want to know if my child would have Down's or anything else, it didn't matter. I wanted just want I got and I got Jeremy, Riley and Lily...just as it should be.
This woman is a true monster. She is Hitler reincarnated.

Scary Singer

Singer is so ignorant. Just because she has other family members with autism then everyone else is wrong about vaccines? How could Autism Speaks have kept her for so long? Talk about narrow minded.

Where would you like to see the research money go?
I think the genetics work has the potential to point us toward important answers. When we can determine which proteins are associated with various genes we can start to understand the mechanism of action that causes autism. Once you understand the mechanism of action, you can start to look for targeted therapies. I would also focus on prenatal exposures. What is a mom exposed to during pregnancy with regard to hormones or maybe medications or even pesticides? Or what's happening in the environment? During flu season, people are more prone to infections so we should look at the incidence of viral infections, flu, hormonal fluctuations and toxins in the environment for both mother and baby.

How is your daughter doing now?
Jodie has benefited tremendously from applied behavioral analysis therapy. She has learned to have some actual communicative speech. She's able to make her wants and needs known. That's really a breakthrough. For three years, she was in private school that focused intensively on language. She gained enough skills to be in a special class in a public middle school. She's not mainstreamed, but she's able to be in that large environment. So she's making great progress.

What do you think caused your daughter's autism?
Jodie had difficulties from the day she was born. She cried constantly, she had difficulty feeding, difficulty sleeping. She was diagnosed in the first few days as having "failure to thrive." I also have a brother diagnosed with autism. He's 44. My first cousin has a son diagnosed with autism. I strongly believe that there is a genetic component.

What do you say to the families who believe their child's autism was triggered by vaccines?
It's very hard because people feel very strongly and love their families so much. But not all opinions are created equal. Some are based on fact and science and some are not. Do you remember when Jenny McCarthy went on Oprah? She said she doesn't need science. Her science is at home and his name is Evan. That's not science.

Here's another story. A few weeks ago, Jodie went to the pediatrician. She had Tdap [tetanus-diptheria-pertussis] vaccine, a flu shot and a vaccine against meningitis. The next day her teacher remarked to me that Jodie was much more attentive and participated in class much more than usual. Her gym teacher said that for the fist time Jodie was able to compete in an obstacle course. Should I start pontificating that vaccines are a great treatment for autism? Of course not, that's not science. That's called coincidence.


So Big Pharma is recruiting parents of ASD kids. Surprise surprise.
The Dr. Peter Hotez model. With no documentation that vaccines were not in fact implicated in their children's regression. No biological testing, no genetics for impaired detox, scopes or metal tests.
Yet they can close the case?
I don't think so?
Some of us, like the Polings, have stacks of medical evidence that says otherwise.
This should make Newsweek and why doesn't it.? Perhaps because 1/3rd of Newsweek's ad revenue is all Pharma.
I miss the free press. Unfortunately the new glossy bias press will not drown out the voice of 1:150/1:67(DOE)who want honest answers.
If the issue was settled there would not be 5000 families in vaccine court.
The Polings would not have gotten a concession.
More Brouhaha.

K Fuller Yuba City

Amazing how one person can end up doing more harm than good. I would not trade places with her. Maybe it is not too late for her to open her mind and see all sides of the issue. I can't imagine that this is what she imagined when she started down this road. If she really is aligning herself against the majority well then God bless her, she is going to need it.


As mentioned in another thread (apologies for the redundancy but it's an important point IMHO) - Jon Meacham (Newsweek editor - at least at the time of the invertivew) essentially admitted to Jon Stewart that today's "reporting" is an exercise in mediocrity. Eat the slop you're fed or go hungry. Claudia Kalb is a poster child for this arrangement.

As far as this recent development is concerned, it can only leave a rational parent asking the question "why" (yet again) - if these guys are trying to implode, they're doing a great job.


They found the cause of AIDs in a few months they found treatment in a few years, 15 years after the surge in Autism they have no clue what causes autism and no clue how to treat it.
They claim that have spent millions looking under every rock for a cause and treatment.
The only thing they know after years of supposed research is that autism is not vaccine related and cannot be treated biomedically.
They will not look at vaccines as a potential cause(because they already have and did not like the results).
We now have additional confirmation by their actions,inactions and propaganda in this area to know that autism must be related to vaccines


Just shut up Offit!

"Paul Offit: "It's been asked and answered: Vaccines don't cause autism," Offit says."

It defies logic, this statement. You can say that with certainty ONLY if you have, without doubt, established something else as causing autism. And - you haven't.

And for journalists to spew this tripe without even thinking about what it means, is truly pathetic. FYI, there are no genetic epidemics. It IS the environment.

Which was it?

So - was she fired? Or did she get a better job (from Big Pharma?)?

If it was the latter, there still isn't hope for Autism Speaks because it still isn't calling the shots on anything that would be of significance to the biomed autism community.


Thanks JB, you actually made me smile in the midst of the angst of her vote at the IACC. I hope Singer enjoys her five minutes of fame because she will be logged in history as a self serving, lying embarrassment to the rest of the autism community.

David Taylor

"The question has been asked and answered" is a talking point. Somebody is giving them out to coordinate the campaign, and obviously the field soldiers are parroting them.

To think that Singer's resignation and subsequent public statements were not choreographed would be grossly naive these days.

Anne Dachel

Reporter Claudia Kalb was the perfect choice to write about Alison Singer's departure from the IACC. The title, The Question has been Asked and Answered, is interesting. I'd like to remind Alison Singer, Claudia Kalb, and especially Paul Offit of the words of former NIH head Dr. Bernadine Healy on CBS News May 12. (CBS News Exclusive: Former Head Of NIH Says Government Too Quick To Dismiss Possible Link Healy directly contradicted Newsweek when she called for studies on the susceptible subgroup of children who unable to eliminate the toxins in vaccines. Her admission that there hasn't been enough research and that epidemiological studies are not proof was a major step toward public recognition about what's happened to our children. Healy also left us with the haunting statement on CBS: 'The question has not been answered.'
That CBS interview should have gotten the attention of Newsweek, but it didn't. On Nov. 3, Kalb had the story, Stomping Through A Medical Minefield , a glowing defense of Offit and his book, Autism False Prophets. Kalb has continued to be a spokesperson for Paul Offit and those financially tied to the vaccine makers and who also refuse to address what's happening to our children.

Anne Dachel
Media editor


Actually I disagree with calling Ms. Singer a "media whore." A google search of her name turns up precious little. She hasn't inserted herself into the limelight at all, despite her high profile job with AS. That's not a defense of her, simply my opinion of use of the term "media whore" which is more appropriate for Paul Offit.


I think someone should take a poll of parent's who have children with autism. What percentage of these families have NO history of developmental delay in their ancestry? I'm in that category.

I'm from a family of ten, my parents had 2 and 4 siblings each, their parents were fairly large families (my paternal great-grandfather had 8 kids). We regularly see quite a few of these 2nd and 3rd cousins (our family reunions are quite large). NONE of them have any children with significant developmental delays.

If it's genetics then my wife was impregnated by an alien.

Teresa Conrick

The narcissism of these crazy Offit proponents never ceases to amaze me. Alison Singer is yet another puppet to the puppeteer(s), another pod under the bed (see Invasion of the Body Snatchers), and another stooge.

Her ridiculous and offensive rationale of not voting for the vaccine research had to do with money?! It was reported that this research would cost $16 million, less than two percent of the available funds of $940 million, so her reasoning is without merit. Her grandiose and absurd part in this saga is maybe a foreshadowing of things to come -- the hungry lie becoming bigger, morphing into other lies until the fabricators have no shred of truth and no supporters.

My appreciation to Autism Speaks for doing the right thing!


Tepper-Singer is just yet another media whore who would be better off addressing her child's needs rather than seeking publicity for herself. So many of them that claim to represent Autism Speaks and therefore autistic kids everywhere are truly a pathetic bunch. Until the media whores of Autism Speaks are gone, more of the same will continue from that organization--all talk and no action for the kids.


It just amazes me that this "it's only the gene theory" is still being reported again and again. More and more previously mainstream doctors are writing books about "the revolution in the medical field that is similar to the earth is flat theory" like His website and his new book Ultraprevention are right on.

He himself experienced "broken brain" after being poisoned by mercury amalgams and mercury laden air not to mention the vaccines I'm sure he received as a health care provider. He lays out the cascade of health issues related to toxicity and how you can help the body repair. He explains that one third to one half of the population has inadequate detox genes, so Allison and Offit better be prepared for a whole society of "broken brains".

His site has some great recipes. I also read Food and Wine that buckwheat is the latest trend food. That right there says a lot.

María Luján

In times when science is bringing us this kind of research
J Autism Dev Disord. 2009 Jan 16.
Brief Report: On the Concordance Percentages for Autistic Spectrum Disorder of Twins.Bohm HV, Stewart MG.
Department of Physics and Astronomy, Wayne State University, Detroit, MI, 48202, USA,
In the development of genetic theories of Autistic Spectrum Disorder (ASD) various characteristics of monozygotic (MZ) and dizygotic (DZ) twins are often considered. This paper sets forth a possible refinement in the interpretation of the MZ twin concordance percentages for ASD underlying such genetic theories, and, drawing the consequences from that refinement, a possible early environmental factor in the later development of ASD.
The research on twins has been one of the main arguments of the genetic theory...

J Autism Dev Disord. 2009 Jan 16.
Trends in US Autism Research Funding.Singh J, Illes J, Lazzeroni L, Hallmayer J.
Stanford Center for Biomedical Ethics, Center for Integration of Research on Genetics and Ethics, Stanford University, Palo Alto, CA, USA.

This study shows that the number of autism research grants funded in the US from 1997 to 2006 significantly increased 15% per year. Although the majority of projects were concentrated in basic science (65%) compared to clinical (15%) and translational research (20%), there is a significant decrease in the proportion of basic research grants per year and a significant increase in the proportion of translational projects per year. The number of translational projects funded by the National Alliance for Autism Research and Cure Autism Now increased significantly, whereas the number of clinical projects significantly increased for the National Institutes of Health. In conclusion, this study demonstrates the shifting landscape of autism research from basic science to clinical and translational research.

Brain Behav Immun. 2008 Dec 25. Increased IgG4 levels in children with autism disorder.Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P.
Department of Medical Microbiology and Immunology, 2805, 50th Street, Wet lab building, Sacramento, CA 95817, USA; The Medical Investigation of Neurodevelopmental Disorders (M.I.N.D.) Institute, University of California at Davis, CA, USA.

Accumulating evidence indicates that immune dysfunction is associated with autism disorders in a significant subset of children. Previous reports have shown abnormal immunoglobulin (Ig) levels, including an increased presence of autoreactive antibodies in the circulation of individuals with autism. As IgG is the predominant antibody isotype in circulation, we expected that an altered immune response could result in an abnormal IgG subclass profile in children with autism. We examined circulating plasma levels of IgG1, IgG2, IgG3, and IgG4 in 241 children from the CHARGE (Childhood Autism Risks from Genetics and the Environment) study, a large epidemiologic case-control investigation, including 114 children who meet full criteria for autism disorder (AU), 96 typically developing control children (TD) from a randomly selected sample of the general population, and 31 children with developmental delays (DD). We report significantly increased levels of the IgG4 subclass in children with AU compared with TD control children (p=0.016) and compared with DD controls (p=0.041). These results may suggest an underlying immunological abnormality in AU subjects resulting in elevated IgG4 production. Further investigation is necessary to elucidate the relationship between immunological findings and behavioral impairments in autism.

Besides the recent epi study of a potential true increase, makes me think that the opinions of Mrs Singer and others about genetics as the main research topic are based on beliefs more than on the on-going findings of recent researcha.

Stagmom's though one step further

To follow-up Stagmom's thought further, the neurodiverse crowd who want to take pride in their autism need to understand that once the susceptibility genes (not causative genes) are all discovered, it will be a recipe for mass abortions with a nice clean $1000 gene chip sold by biotech firms to expecting parents. In the endgame of this cabal with Offit and Singer, the neurodiverse have been allied, then children with these "defects" (R. Jenkins AAP term) will be eliminated Nazi style!!!!!!!!!!

Harvey Karp "KARP: Which disease do you want your child to get?" Larry King april 2, 2008
IMO "Any of them but Autism"

Kevin Barry

1-2% of those on the spectrum have a primarily genetic condition. That 1-2% gets 95% or the research funding. Alison's family may be in that 1-2%. She likes the 95% for 1-2% of the population split.

Autism Speaks enabled Alison to ignore 98% of those on the spectrum.

Cindy Waeltermann

She will rear her ugly head, mark my ECBT. The simple fact that they issued the press release, which costs money, mind you, indicates to me that she will pop up there in some highly-paid pharmaceutical position.

They'll tout her as "look, here's a mom of a child with autism who doesn't believe the vaccine theory..."

The AAP and physicians all over the world will hail her as a hero. She will be well-loved in that community, but hated in ours.



Singer, in my opinion, has done absolutely nothing to help those with autism so why is this woman speaking for the kids at all? As she mindlessly denies any connection of vaccines to autism and alligns herself with disgusting people like the Offits of the world, the only solution she ever seemed to contribute was driving her daughter off a bridge. She truly is a horrible excuse of an advocate for autism. I hope we see more of them at Autism Speaks go because their main interest seems to be their own publicity, not the children. They need to clean house at Autism Speaks.


Christina, it would appear that there is a symbiosis between then. Ms Singer has a child with autism and a brother with autism and appears to be fully invested in the genetics theory that removes all responsibility for the autism. Dr. Offit's quest is to make certain vaccines, his life's work, are never implicated in any injury, most of all, autism. Wyeth is a corporation and as such, needs all of its products to sell well to survive. I'd call it a cabal. A parasitic pairing.

And for the Neurodiversity component of the autism world, Singer is no hero, after having declared that statement about her daughter and a bridge. (That statement horrified me equally.) They should continue to be gravely concerned as the push goes on for prenatal testing, the ultimate goal of genetics research in general. Alison Singer will likely continue to support genetics research in an effort to keep vaccines off the table - and the slippery slope to aborting fetuses who have a possibility of becoming autistic will turn into Mt. Everest. No, instead of finding out what's triggering that possible genetics and preventing the autism, allowing the baby to be born and develop into a very smart, highly productive member of society, her life's work will lead to a slew of new stems cells, ready to harvest....

Christna Liberatore

Wyeth, Offit and Singer must be friends?

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