Annette,

Thank you for commenting. We are going to try Enhansa. My daughter has had yeast for years. Hopefully, this will make a big difference.

Just wanted to drop you a quick note to let you know how much better our son, Ryan, is doing on your Curcumin (Enhansa). As you know we have been battling yeast/fungus for years. When we first started Curcumin (Enhansa), I ignored your directions of starting at 150mg once every other day thinking, Ryan has been on so many anti-fungals in combinations and at huge doses that there was no way he would need to titrate up. What a die-off reaction, I was very impressed but immediately starting following the directions.

Anyway after Ryan was on 600mg once daily we saw such great improvement both socially, communicatively, and in physical symptoms (coated tongue, anal ring) that we were able to slowly discontinue all of his prescription anti-fungal medications. So there went Lamsil, ketoconazole, fluconazole, itraconazole, and Amphotercin B.
After being on Curcumin (Enhansa) for a few months, I decided to switch to an over-the-counter curcumin product from a great company. However within a month, Ryan’s yeast had flared so bad that we needed to redo the antifungal parade. Once again it was not until I returned to your Curcumin (Enhansa) did I get Ryan’s yeast back under control.

We have a great mom’s group and several of the moms in the group have also found your Curcumin (Enhansa) to be far superior to other curcumin products as well.

So needless to say we are going to remain on it. What I have noticed is that at higher doses like 600mg twice to 3 times daily I see even greater cognitive effects. After several months of playing with his regimen I truly think your Curcumin (Enhansa) is also working as an anti-inflammatory agent. I use it in combination with HBOT and pycnogenol and he is making great gains in all areas.

Thank you again and keep making those wonderful products.

Sommer, I heard through the grapevine Amy Yasko said that if she was stuck on a deserted island Curcumin would be the one supplement she would take with her.
It's in her protocol.
We opted for her inflammation (Boswellia, Curcumin,Nettle-Puzzle book) trio from the puzzle book over prescriptives to keep neopterins in check.
Worked great!
Check this out from Hyper health:
http://www.hyperhealth.com/
Description
Curcumin is a type of Phenolic Acid Curcuminoid that is a derivative of Cinnamic Acid.

Health Benefits of Curcumin

Curcumin (administered within 30 minutes after the occurrence of (ischemic) Stroke) may reduce the toxic effects of Ischemia/Reperfusion injury in the Brain after (ischemic) Stroke.

Digestive System

Curcumin may help to prevent or treat Colitis.
Curcumin may lower elevated Tumor Necrosis Factor (TNF) levels in Crohn’s Disease patients and may help to reduce Intestinal Permeability in Crohn’s Disease patients.

Curcumin may help to prevent Gastric Ulcers (including those caused by excessive consumption of Alcohol [ethanol] and those caused by Helicobacter pylori infection). references
Curcumin may alleviate Irritable Bowel Syndrome (due to its ability to inhibit Inflammation).

Excretory System

Curcumin may reduce the Kidney damage (diabetic Nephropathy) that occurs in Diabetes Mellitus patients: references

- Curcumin may reduce the Kidney damage (diabetic Nephropathy) that occurs in Diabetes Mellitus Type 1 patients:
- Curcumin may reduce the Kidney damage (diabetic Nephropathy) that occurs in Diabetes Mellitus Type 2 patients:
- Curcumin may reduce Gentamicin-induced Kidney damage.

Immune System: Cancer

Curcumin may help to prevent the development of and inhibits the further growth of some forms of Cancer.
- Curcumin may stimulate the Apoptosis (cellular “suicide”) of some types of Cancer cells.
- Curcumin may stimulate apoptosis (cell death) in Astrocytomas.
- Curcumin may help to prevent Bladder Cancer.
- Curcumin may help to prevent Breast Cancer.
- Curcumin may help to prevent Cervical Cancer.
- Curcumin may help to prevent Colon Cancer. references
- Curcumin may help to prevent Duodenal Cancer.
- Curcumin may be useful for the treatment of Gliomas.
- Curcumin may cause the Apoptosis (death) of the Cancer Cells involved in the Acute Promyelocytic Leukemia form of Leukemia:
- Curcumin may stimulate the apoptosis (death) of Acute Lymphocytic Leukemia (ALL) cells.
- Curcumin may be useful for the treatment of Chronic Myelogenous Leukemia.
- Curcumin may help to prevent Liver Cancer (including Nitrosamines-induced Liver Cancer).
- Curcumin may help to prevent Lung Cancer.
- Curcumin may stimulate the apoptosis (cell death) of (Non-Hodgkin’s) Lymphoma cells. references
- Curcumin may inhibit the metastasis of Melanoma.
- Curcumin may help to prevent Mouth Cancer:
- Curcumin may help to prevent Tongue Cancer.
- Curcumin may be useful for the treatment of Neuroblastoma.
- Curcumin may help to prevent and treat Ovarian Cancer.
- Curcumin may inhibit the growth of Pancreatic Cancer.
- Curcumin may help to prevent and treat Prostate Cancer.
- Curcumin may help to prevent and treat Pharyngeal Cancer.
- Curcumin (applied topically or ingested orally) helps to prevent carcinogen-induced Skin Cancer.
- Curcumin may help to prevent Stomach Cancer.
- One of the means by which Curcumin may exert its anti-Cancer properties is by stimulating the p53 Tumor Suppressor Gene to produce the p53 Protein.
Curcumin may help to prevent Leukoplakia from progressing to Mouth Cancer.

Immune System: Pathogens
Curcumin may be a valuable treatment for Acquired Immune Deficiency Syndrome (AIDS) patients:

- Curcumin may inhibit the Integrase enzyme that catalyzes part of the process involved in the replication of the HIV virus.
- Curcumin may interfere with the Long Terminal Repeat (LTR) sequence of the HIV virus.
- Curcumin may increase the Helper T-Cell count of Acquired Immune Deficiency Syndrome (AIDS) patients - in one study the oral administration of 2,000 mg of Curcumin per day to AIDS patients for 20 weeks resulted in an increase in average Helper T-Cell counts from 6 - 615 cells per ml of blood to 283 - 1,467 cells per ml of blood. references

Curcumin may inhibit the reactivation of the Epstein-Barr Virus in persons previously exposed to this Virus. references
Curcumin may inhibit Helicobacter pylori. references
Curcumin may be an effective treatment for Malaria. references

Curcumin may inhibit/kill Plasmodium berghei. references
Curcumin may inhibit/kill Plasmodium falciparum. references

Immune System: Underlying Mechanisms

Curcumin may stimulate various aspects of the Immune System:

- Curcumin may increase the production of Antibodies.
- Curcumin may enhance the ability of Macrophages to function as Phagocytes. references
- Curcumin may increase the body’s production of White Blood Cells. references

Curcumin may be equally as effective as (and less expensive than) Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for the treatment of Inflammation and the various ailments associated with Inflammation: references

- Curcumin’s mechanism of action in the suppression of Inflammation is believed to be via increasing the endogenous secretion of Cortisol; increasing the sensitivity of Glucocorticoid Receptors to Cortisol; and increasing the half-life of endogenous Cortisol by retarding its degradation within the Liver.
- Curcumin may reduce the Inflammation that usually occurs following Surgery.

Metabolism

Curcumin possesses potent Antioxidant properties: references

- Curcumin scavenges Peroxynitrite Free Radicals.
- Curcumin quenches Singlet Oxygen Free Radicals.
- Curcumin quenches Superoxide Free Radicals.
- Curcumin has been shown to be equal in Antioxidant potency to Butylated Hydroxyanisole (BHA).

Curcumin may lower total serum Cholesterol levels: references

- Curcumin may increase HDL Cholesterol levels by up to 29%. references
- Curcumin may lower LDL Cholesterol levels. references
Curcumin may also inhibit the oxidation of LDL Cholesterol.

Curcumin may be beneficial for Cystic Fibrosis patients.
Curcumin may reduce the Kidney damage (diabetic Nephropathy) that occurs in Diabetes Mellitus patients: references

- Curcumin may reduce the Kidney damage (diabetic Nephropathy) that occurs in Diabetes Mellitus Type 1 patients. references
- Curcumin may reduce the Kidney damage (diabetic Nephropathy) that occurs in Diabetes Mellitus Type 2 patients. references

Curcumin enhances the function of the Liver: references

- Curcumin exerts Antioxidant effects in the Liver.
- Curcumin may help to reverse the Liver damage caused by Aflatoxin.
- Curcumin may help to prevent Cirrhosis. references
- Curcumin may suppress the damage to Liver cells (hepatocytes) caused by Hepatitis C.
- Curcumin may stimulate the production of Glutathione by the Liver.

- Curcumin may inhibit the deposition of Triglycerides in the Liver.

Curcumin may lower total serum Triglycerides levels and may inhibit the deposition of Triglycerides in the Liver. references

Musculoskeletal System

Curcumin may help to prevent/treat Osteoarthritis (by inhibiting the toxic effects of Interleukin 1).
Curcumin (1,200 - 2,600 mg per day) may alleviate the Inflammation associated with Rheumatoid Arthritis. It may also reduce morning stiffness and increases walking time in Rheumatoid Arthritis patients. Part of this effect occurs from Curcumin inhibiting the Cyclooxygenase-2 (COX-2) enzyme. references

Curcumin may help to prevent Scleroderma. references

Nervous System

Curcumin may help to prevent and treat Alzheimer’s Disease (due to the ability of Curcumin to counteract the toxic effects of Amyloid-Beta Protein). references
Curcumin may be useful for the prevention or treatment of Bovine Spongiform Encephalopathy (BSE) (Mad Cow Disease). references

Curcumin may counteract the Brain damage caused by Alcohol (ethanol). references
Curcumin may help to prevent and treat Depression. references
Curcumin may inhibit the excessive proliferation of Glial Cells (a condition known as Gliosis). references

Curcumin (administered prior to the occurrence of a Head Injury) may minimize the cognitive impairment that occurs as a result of Head Injuries. references
Curcumin may inhibit the further progression of Multiple Sclerosis (MS). references
Curcumin may help to prevent Parkinson’s Disease. references

Respiratory System

Curcumin may be useful for the treatment of Acute Respiratory Distress Syndrome. references
Curcumin may protect against Lung damage caused by various toxic substances. references

Curcumin (consumed orally or applied topically) may accelerate the healing of Wounds. references

Curcumin may Enhance the Function of these Substances

Immune System Chemicals

Curcumin may stimulate the production of Interleukin 4. [more info]

Lipids

Curcumin may enhance the secretion of Prostaglandin F1 alpha. references

Peptides

Curcumin may stimulate the production of Glutathione by the Liver. references

Polyphenols

Curcumin is synergistic with Epigallo-Catechin-Gallate (EGCG) (in terms of the ability of EGCG to prevent Mouth Cancer). references

Curcumin may Counteract these Potentially Toxic Substances

Amines

Curcumin may reduce the toxicity of Heterocyclic Aromatic Amines (HAAs). references
Curcumin may inhibit the ability of Nitrosamines to cause Liver Cancer. references

Amino Acids

Curcumin may counteract the toxic cardiovascular effects of Homocysteine. references

Enzymes

Curcumin may inhibit the Cyclooxygenase-2 (COX-2) enzyme. references
Curcumin may inhibit the Integrase enzyme that catalyzes part of the process involved in the replication of the HIV virus. references
Curcumin may inhibit the 5-Lipoxygenase form of Lipoxygenase. references

Curcumin may inhibit Ornithine Decarboxylase (an enzyme that is implicated in various types of Cancer). references
Curcumin may inhibit Protein Kinase C. references

Hormones

Curcumin may inhibit Platelet Aggregating Factor (PAF). references

Immune System Chemicals

Curcumin may inhibit the toxici effects caused by Interleukin 1. references
Curcumin may inhibit the release of Interleukin 8 in respiratory system cells. references

Lipids

Curcumin may inhibit Leukotriene B4. references
Curcumin may inhibit Leukotriene C4. references
Curcumin may inhibit Prostaglandin E2 (PGE2). references
Curcumin may inhibit Thromboxane A2 (TXA2). references

Microorganisms

Curcumin may help to reverse the Liver damage caused by Aflatoxin. references

Minerals

Curcumin may facilitate the removal (chelation) of excess Iron from the body. references
Curcumin may help to prevent Lead-induced Brain damage.

Pesticides

Curcumin may partially block the toxicity of Dioxin (Curcumin competes with Dioxin for binding to the Aryl Hydrocarbon Receptor - however Dioxin is a more potent Aryl Hydrocarbon Receptor agonist compared to Curcumin and therefore Curcumin can only partially block the effects of Dioxin). references

Proteins

Curcumin may downregulate Activator Protein 1 (AP-1). references
Curcumin may inhibit the neurotoxic effects of Amyloid-Beta Protein. references
Curcumin may help to lower elevated C-Reactive Protein levels. references

Curcumin may inhibit Nuclear Factor-Kappa B. references

These Substances may Enhance the Function of Curcumin

Amides

Piperine (Bioperin) may increase the oral bioavailability of Curcumin (by 2,000% (twenty-fold)). references

Enzymes

Bromelain may enhance the oral bioavailability of Curcumin. [more info]
Papain may enhance the oral bioavailability of Curcumin. [more info]

- If Curcumin is ingested orally at the same time as a high fat meal, its oral absorption is increased.

When consumed orally, serum levels of Curcumin peak at one to two hours after Curcumin intake. Serum levels of Curcumin then gradually decline over a period of 12 hours.

The general therapeutic dosage of Curcumin for healthy persons seeking to prevent Cancer is 900 - 1,800 mg per day.
The recommended dosage of Curcumin for Cancer patients (who seek to “kill” their tumors via apoptosis) is 2,000 - 8,000 mg per day.
The effective dosage of Curcumin for Rheumatoid Arthritis patients is 1,200 - 2,600 mg per day.

Clinical trials using Curcumin have employed an average of 2,600 mg per day.

In-Tele-Health © 2006 (from Hyperhealth Pro CD-ROM)

Curcumin has been a fantastic supplement for us but I didn't realize the full effect until I sprained my ankle. When the Motrin wore off and I refused potent prescriptive pain killers, I opted instead to raid my son's supplement drawer.
Curcumin worked like a charm.
The only problem is it is not well absorbed.
Kudos to LS for taking this a step further.
Sure beats prescriptive anti-inflam options.
Antimutagenic,Anti-inflam,helps curb ammonia,kills yeast, Anti-oxidant.
What's not to love???

Lee Silsby was the very first pharmacy I used when I started biomed for the girls. Talk about your experts... They walked me through so many questions. I'm honored that they wanted to sponsor A of A. They are good people. Plain and simple. Good people.

KIM