Dr. Jenkins, Want to Rethink Your Position?
The United Mitochondrial Disease Foundation (UMDF) today announced landmark research finding that one in every 200 people has a DNA mutation that could potentially cause a mitochondrial disease in them or their offspring. Mitochondrial disease is a devastating and often fatal disease, and mitochondrial disorders are at the core of many well known diseases and chronic illnesses, such as Alzheimer's disease, Parkinson's disease and autism spectrum disorders. Click HERE to read more.
When was the last time the prevalence of mito. disorders in the general population was investigated using cord blood, or what this the first time they ever did it this way? If it was ever done before and the incidence was 1-4,000 then obviously the big question becomes why has it increased by 20-fold in (potentially) recent years. Obviously, one thinks of mercury contamination in the environment, but I also wonder how many more pregnant women have been getting the flu shot in recent years with all of the push from the vaccine makers.
Posted by: Rachel Ford | August 19, 2008 at 04:16 PM
It is curiously dismal that we have not heard a peep out of Julie Gerberding since she admitted to Sanjay Gupta that vaccines can cause damage that leads to autism.
So in light of this most recent news I wrote the following song (to the tune of "Where have you gone, Joe DiMaggio"):
Where have you gone, Julie Gerberding
Injured children line up at your door
Woe, oh, oh
Where have you gone, Julie Gerberding,
Renee Jenkins cannot take your place--
Its getting late.
You dropped the ball, Julie Gerberding,
Parents have done all that they can do...
Docs look to you.
We need your help, Julie Gerberding,
Tell the docs to spread out the shots,
Right away!
We know you lied, Julie Gerberding,
Mitochond. dyfunction isn't rare.
Its all too there.
Its way past time, Julie Gerberding,
Babies are in line for shots today.
Its time to go, Julie Gerberding,
Its time to go!
Posted by: Rachel | August 12, 2008 at 01:02 PM
The other Karen in ATL,
ALA
ALCarnitine
Riboflavin
Thiamine
Co-Q 10 and Hyperbaric Oxygen all support Mitochondria.
Chelation therapy removes toxic heavy metals that provoke oxidative stress.
Most DAN(Defeat Autism Now)doctors can run appropriate testing for suspected mitochondrial disorder. They include testing peruvate and lactate or a muscle biopsy.
Like many other aspects of vaccine induced Autism, mito-disorders are treatable.
If parents know what ails their child that is.
Start by skimming the symptom link at the UMDF.
Posted by: KarenAtlanta | August 11, 2008 at 07:53 PM
FACT: Thimerosal damages DNA. It deletes mitochondria, proven in dozens of studies long before Hannah Poling's VICP case ever conceded.
SAFEMINDS have been imploring the CDC ACIP advisory panel to respectfully state a preference for Thimerosal free vaccines for a decade. Citing Mitochondria damage known in 2004 and developmental damage proven and recorded at a CDC Simpsonwood Meeting in 2000. Along with legitimate primate studies.
Today 11 vaccines contain toxic Thimerosal that other countries have flat out banned.
The CDC ACIP panel, which drives vaccine safety, can't even "prefer" non-toxic Mercury free vaccines????
The most civil, human, thing to do for children is to take reasonable precaution with their developing bodies.
If this study is spun into "See Autism is genetic." I will wretch.
The CDC, the AAP, the NIH have an opportunity here to advise based on the science they have been demanding.
So do it.
You have moral obligation to humanity to do the right thing here.
Don't be scumbags, Pharmawhores any longer.
Redeem yourself before one more kid is lost.
Hopefully it won't be yours.
Posted by: karenatlanta | August 11, 2008 at 07:10 PM
Karen in Atlanta
you said--"Since April we have been treating our extremely fatigued, slow to grow, hypotonic son while we get appropriate testing.
The difference in my kid is night and day."
Do you mind sharing what you have been doing on your own to treat the mito dys, and what doctor in the area you are using for this testing?
Thanks in advance, I greatly appreciate it.
Posted by: to KAREN in ATL | August 11, 2008 at 07:08 PM
Sadly, what's going to happen is the CDC and the pHARMa-scum (tm) are going to spin this and say that they were correct all along and that Autism is purely genetic, they just didn't know it was tied to MT disorder. Again, they are going to try to pull the focus away from the Church of the Immaculate Vaccination and say that their sacred cash cow has nothing to do with MT disorder.
I can honestly say I'm losing hope that these slimes will ever receive the justice they deserve.
Posted by: Craig Willoughby | August 11, 2008 at 06:27 PM
To Jeff:
While the government debates over which test really proves mito, get an Metamatirix ION panel or test blood levels of lactate and puruvate.
I actually know someone who had a muscle biopsy and another RN who had the genetics done, both found themselves with physicians still refusing admit mito disorder was the problem.
It is a controversial and polarizing topic now, since the Hannah Poling case.
Any parent can read the symptom list on the United Mitochondrial Disorder webpage and read up on this disease that mirrors everyday Autism.
Since April we have been treating our extremely fatigued, slow to grow, hypotonic son while we get appropriate testing.
The difference in my kid is night and day.
He had 18 of the symptoms listed here.
http://www.umdf.org/site/c.dnJEKLNqFoG/b.3041929/
He also had DTaP, HIB and HEP B with with full strength "mito deleting" Thimerosal in his infant vaccines.
The Mito foundation says "Think Mitochondria when 3 or more organ systems are involved."
HA!
Think Autism.
Gut
Brain
Endocrine
Lymphatic
Nervous System
Muscles
Do we need a brick to fall out of heaven to make a connection here!
Posted by: karenatlanta | August 11, 2008 at 06:19 PM
I wonder how quickly can labs here be ready to perform the same test(s) that Dr. Chinnery et al have done. This blood based test is certainly preferable to a muscle biopsy for spectrum children. The next step is for a significant portion of our children to get this test as well as children's parents. This may well provide the link to vaccine susceptability. It may also enable detection of susceptability in infants and there stop the continued ravaging of our children.
Posted by: Jeff Stone | August 11, 2008 at 05:24 PM
HELLO MCFLY!
We review the previous literature and recent results from our own laboratories, and conclude that mtDNA deletions are most likely to occur during repair of damaged mtDNA rather than during replication.
1: Nat Genet. 2008 Mar;40(3):275-9.Click here to read Links
What causes mitochondrial DNA deletions in human cells?
Krishnan KJ, Reeve AK, Samuels DC, Chinnery PF, Blackwood JK, Taylor RW, Wanrooij S, Spelbrink JN, Lightowlers RN, Turnbull DM.
So what damages Mito?
Michelle L. Humphreya, Marsha P. Coleb, James C. Pendergrassc and Kinsley K. Kininghama, ,
aDepartment of Pharmacology, Joan C. Edwards School of Medicine, Marshall University, Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40536, USA
cAffinity Labeling Technologies, Inc., Lexington, KY 40508, USA
Received 6 December 2004; accepted 25 February 2005. Available online 24 May 2005.
Abstract
Environmental exposure to mercurials continues to be a public health issue due to their deleterious effects on immune, renal and neurological function. Recently the safety of thimerosal, an ethyl mercury-containing preservative used in vaccines, has been questioned due to exposure of infants during immunization. Mercurials have been reported to cause apoptosis in cultured neurons; however, the signaling pathways resulting in cell death have not been well characterized. Therefore, the objective of this study was to identify the mode of cell death in an in vitro model of thimerosal-induced neurotoxicity, and more specifically, to elucidate signaling pathways which might serve as pharmacological targets. Within 2 h of thimerosal exposure (5 μM) to the human neuroblastoma cell line, SK-N-SH, morphological changes, including membrane alterations and cell shrinkage, were observed. Cell viability, assessed by measurement of lactate dehydrogenase (LDH) activity in the medium, as well as the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay, showed a time- and concentration-dependent decrease in cell survival upon thimerosal exposure.
In cells treated for 24 h with thimerosal, fluorescence microscopy indicated cells undergoing both apoptosis and oncosis/necrosis.
To identify the apoptotic pathway associated with thimerosal-mediated cell death, we first evaluated the mitochondrial cascade, as both inorganic and organic mercurials have been reported to accumulate in the organelle. Cytochrome c was shown to leak from the mitochondria, followed by caspase 9 cleavage within 8 h of treatment. In addition, poly(ADP-ribose) polymerase (PARP) was cleaved to form a 85 kDa fragment following maximal caspase 3 activation at 24 h.
Taken together these findings suggest deleterious effects on the cytoarchitecture by thimerosal and initiation of mitochondrial-mediated apoptosis.
Keywords: Mercury; Thimerosal; Mitochondria; Neurotoxicity
Posted by: karenatlanta | August 11, 2008 at 05:04 PM
This same mito foundation has been saying, on it's well publicized webpage, "every 15 minutes a child under 10 is diagnosed!"
Yet our CENTER for disease CONTROL says this:
Julie Gerberding, the head of the CDC
on Hannah Poling:
"This is a complete mischaracterization of the findings of a very simple situation of one child with an ***unusual disorder***, and it would be completely wrong to say that this has bearing to the vast majority of children with autism,"
Reform the CDC.
It cannot regulate and mandate vaccines.
Really it doesn't know it's butt from a hole in the ground - and much less on prevalence of mitochondria disorders.
So statistically you have a 1:200 chance of getting Autism like Hannah Poling.
Interesting that 200 is not far from another number we know all to well...150.
How long can the media stay silent here?
Posted by: karenatlanta | August 11, 2008 at 04:42 PM
I wonder what Dr. Jenkins thinks of this...more "defects"...or the same?
Posted by: Barbie Hines | August 11, 2008 at 04:24 PM
This is huge. Could this mean a huge portion of th population is walking around with a mito timebomb ready to explode when met with the right environmental trigger??
I'm anxious to see more studies on this.
Posted by: Angela S. | August 11, 2008 at 03:18 PM
Well... I most certainly think she should or would want to rethink her position.
1 in 200 is strikingly close to 1 in 150 (the continued CDC number from years ago). I wonder if all those people who happen to be the 1 in 200 will be cast as throwaway's as our children with autism have. Nope sorry... you have a "defect" - we there fore can not treat you...
I wonder how many individuals at the CDC, AAP, FDA, etc. would be included in the 1 in 200 if tested. Maybe Renee Jenkins is "defective" thus her continued stance?
Sickening... and very sad... the research however is extremely important and will hopefully enlighten the MANY who need enlightenment!
Posted by: Angela Warner | August 11, 2008 at 03:10 PM