Note: This post is part of an on-going series by Teresa Conrick. You can read more about the Microbiome in our "Exclusives" pull down menu.
By Teresa Conrick
On August 29th, 1931, Vivian Murdock was born in Maryland. She was to become Case 6, Virginia S. , the eldest diagnosed of those unique childrenas reported by Dr. Leo Kanner in his famous paper from 1943 . He changed her name and birthday as he knew her father, Dr. Harry Murdock, a fellow psychiatrist, and presumably wanted to keep the family anonymous.
Here is her Social Security death notice:
Last Residence: 21838 Marion Station, Somerset
Maryland, United States of America
Born: 29 Aug 1931
Died: Jan 1987
State (Year) SSN issued: Maryland (1975)
On April 14th, 2012, I “found” Virginia S. after years of searching. Her life of institutionalization since 1936 was horrific and compelled me to keep up my search through volumes of documents. Virginia S. was my Titanic, a monumental and historic tragedy of both mind and body that had clues to MAN as the culprit. I needed to find her and thought of it as a rescue mission. I have a daughter, like Virginia S., who has been nonverbal since regression into an autism diagnosis after her vaccinations. State mental hospitals and institutions were the options for autism in the days of Kanner and since. In present day, we now see that the majority of cases involve REGRESSION, with increasing numbers of parents reporting VACCINATION as the cause. I have always been intrigued by the fact that Virginia S. was born in Baltimore right when, “The city health department reported in 1931 that 'during the year the Department began the distribution of diphtheria toxoid on a large scale. ’ ” These would have been the first well-baby vaccines containing mercury. Her family and the other seven discovered so far from those Kanner 11, each had a history of mercury exposure. Both mercury and vaccination can alter the microbiome. NOTE: Antibiotics were not yet in use when those first eleven children were identified.
Since 1938, when Kanner first met those children, autism has become an epidemic and a top fear for expecting parents. Some may try to paint autism as an increasing diagnosed disability, where each individual needs to be treated with dignity. I agree with that but we need to also add that autism is increasing due to environmental, not genetic factors and that for most, autism is a DISEASE, with true, medical markers. It is becoming increasingly clear that the social, language and perseverative behaviors of autism are a consequence of a microbiome that is sick and that in turn affects the brain:
A new and growing area of research is finding that the bugs, especially the ones in our guts, play a critical role in human health and the development of our immune system.
Scientists say that a host of health problems, including autism, cancer, obesity, diabetes, malnutrition, Crohn's disease, asthma and rheumatoid arthritis, seem to appear when the human microbial community gets out of whack.
And this one:
Similarly, a 2013 study from Mazmanian’s lab found that a mouse model with some features of autism had much lower levels of a common gut bacterium called Bacteroides fragilis than did normal mice3. The animals were also stressed, antisocial and had gastrointestinal symptoms often seen in autism. Feeding B. fragilis to the mice reversed the symptoms. The group also found that the mice with these symptoms had higher levels of a bacterial metabolite called 4-ethylphenylsulphate (4EPS) in their blood, and that injecting that chemical into normal mice caused the same behavioural problems..
…. 4-ethylphenylsulfate, was 46 times as abundant in the mice with autism symptoms as in normal mice .
ASD is a collection of neurodevelopmental changes in children where they exhibit complex behavioral changes in their abilities in social interaction and communication, as well as presence of behaviors similar to obsessive–compulsive disorder, including repetitive and narrow interests. While the disease impacts the brain, gastrointestinal symptoms are commonly described in children with ASD (234, 235), and studies have identified the presence of inflammatory infiltrate and histopathology in biopsies of children with ASD, including increased numbers of cytotoxic T cells, CD19+ B-cells, and increased enteric IgG1/4 (236, 237). Possibly related to these GIT immune changes and dysfunction, some studies have demonstrated an altered composition of intestinal microbiota in young children with ASD compared to healthy control children with typical neurological function (238–242)……
….. When identifying a role for the microbiota in ASD, rather than making predictions based on taxonomic sequence data, recent studies have been studying the metabolite secretions of gut microbes and the impact of these microbiotas on host serum metabolites. A potential mechanism behind ASD symptoms could be neuro-active metabolites mediated by or produced by the microbiota, which could disseminate systemically and penetrate the blood–brain barrier.
So, we see more and more research implicating the microbiome in autism and the clues keep also hinting towards vaccines. Here we read “infections” yet those “first days, months, and years of life” are inundated with vaccinations.