NOTE: We're bringing you this series, re-crafted for 2017, by Richard P. Milner of Public Affairs Media. Dr. Paul Offit has led the charge against any and all in our community, doctors, scientists, parents, educators, film makers, who question vaccine safety.
OFFIT: Or maybe we’re just very influenced by what I think are these fringe scientists, frankly, who are perfectly willing to stand up and say, well, I think vaccines cause autism anyway. Even though these data show this and make sort of vague allusions to the fact that people are in the pocket of the pharmaceutical industry, which clearly isn’t true. So I don’t understand it.
HALEY: The last I looked, my research showing autistic infants did not effectively excrete mercury as compared to normals has held up quite well and has been reproduced by others. The oxidative stress with low glutathione levels observed by many others in autistics tells us why they cannot excrete mercury effectively. The urinary Porphyrin profile shows most autistics to have mercury toxicity---and I could go on and on. All of we “fringe” scientists have published scientific data that we present, not the fabricated epidemiology that Offit is wed to.
MILNER: The guys in Calgary took brain neurons and put it on a solution of different heavy metals and what they show on camera is the neuron being torn apart when they put a solution of mercury on there. And as I understand it, it’s elemental mercury. They also say that when they add Aluminum to the mix, it catalyzes. Are you familiar with that? Do you have a response to that? Explain that a different way? [www.youtube.com/watch?v=XU8nSn5Ezd8&t=161s]
OFFIT: No, I think that historically in medicine that studies on laboratory cells or studies in experimental animals are not always predictive of events in children.
HALEY: No, they can be predictive if you go to a level of mechanisms above those presented by Offit. The collection of mercury in the brain and the known specific biochemical reactions or enzymes inhibited by mercury is quite detailed.
Science uses cell culture to show which organ cells can be infected by specific microbes, which cells are more sensitive to specific toxicants, the exact proteins and enzymes inhibited or whose biosynthesis is reduced or increased by specific exposures. Offit appears to have little understanding of how biological science works and plays a role in medicine.
OFFIT: the fact that the disorder of Autism is genetic is not a controversy.
HUMPHRIES: Actually it is very much a controversy. The reason being is that genes do not evolve as rapidly as Autism has. There has been a sharp increase in the prevalence of autism by as much as 2000 % since the early 1990s. The other excuse is often that the diagnosis is being made more aggressively today. Or that the population has increased, but neither of those has risen by 2000%. The diagnostic criteria have changed very little since 1943 when Dr. Kanner first described autism.
MILNER: The critics of the genetic thing would say, well, there’s no such thing as a genetic epidemic. Would you agree with that statement?
OFFIT: I don’t think there’s an epidemic of Autism.
I think if we went into a time machine and went back thirty or forty years and used the same diagnostic criteria that we currently use to diagnose Autism, and introduce it into the community so that everybody is aware as they were—as they are now, and also make it very clear in that community now thirty years in the past that you will qualify for services if you have this diagnosis, I think you would find that the incidence of Autism would be the same thirty years ago as it is now.
HUMPHRIES: Where are all the autistic adults and seniors then??? The fact is that the actual diagnostic criteria have changed very little from the 1943 DSM-IV-TR. So thirty years ago psychiatrists would have made the diagnosis.
BLAYLOCK: This is all nonsense. I suppose the mothers before 1980 were so unobservant or stupid they just didn’t notice their child was severely neurologically affected and their pediatrician failed to notice as well. How could anyone believe this nonsense? This is the same thing they tried for years with the incredible increase in Alzheimer’s disease, Parkinson’s disease and other neurodegenerative diseases—finally after decades of denial neurologists admit that the incidence of neurodegenerative diseases has been grossly underestimated and that it is occurring at a much younger age. It is time for Dr. Offit and his friends to wake up a smell the coffee.
HALEY: In about 1940 the first cases of autism were reported in the medical literature and reported as a neurodevelopmental disorder never seen before. Thimerosal was introduced in the early 1930s into biological vaccines. The rate of autism slowly increased with increased use of thimerosal but took off dramatically in about 1990 after the advent of the CDC mandated vaccine program. Offit is in an absurd state of denial.
OFFIT: If you want to find out whether or not vaccines cause Autism, whether or not MMR causes Autism, whether or not Thimerosal causes Autism, you do a scientific study. And it doesn’t matter what I say. And it doesn’t matter what Boyd  Haley says. And it doesn’t matter what Andrew Wakefield says. And it doesn’t matter what Bernadine Healey says.
HALEY: Boyd Haley published research showing that autistic infants could not effectively excrete mercury, which has been reproduced by two other academic studies. Dr. Jill James showed that autistics suffer from very low levels of glutathione, the molecule that carries mercury from the body further supporting this concept that autistic have lost the ability to excrete mercury.
HALEY: Many research papers have shown that mercury prevents the cellular synthesis of glutathione and thereby the excretion of mercury leading to a retention toxicity of mercury that is well described in the literature also. Dr. Deth has shown that the enzyme methionine synthetase is inhibited by thimerosal at about 1-2 nanomolar levels and this enzyme is inhibited in autistic children.
Again, there are many other scientific studies that strongly support the concept that autistic children represent a subset of the population that cannot effectively excrete mercury and are therefore more seriously affected by the vaccine exposure. The fact that Offit does not want to put value on all of these studies shows that he is not open-minded about any research that shows a weakness or problem with vaccines.
OFFIT: What matters are the strength, reproducibility, and consistency of the data. It’s a scientific question. And it’s had a scientific answer.
HALEY: Yes, I agree that the answer is obvious, but we do disagree on what the answer is.
MILNER: Now what about adjuvants? There’s been thinking adjuvants hyper-excite the immune system. That when we put in Aluminum Hydroxide or Squalene, then we get injuries.
OFFIT: The only adjuvant that is approved for use in the United States is Aluminum salts.
TENPENNY: He really doesn’t know the medical literature or what he is talking about. Vaccines with aluminum hydroxide are DTaP (Infarix), Hep A, HiB, Pediarix, Twinrix and anthrax. Vaccines with aluminum phosphate are DT, DTaP (Daptacel) and Prevnar. Vaccines with Aluminum sulfate are DTaP (Tripedia), dT Combvax and Hep Ba (Recomvax). MF59 is in the anthrax vaccine.
Calculating Aluminum in Vaccines. Here are the current levels of aluminum per shot of the following vaccines, as listed on each vaccine's packaging:
- HIB - PedVax – 225 mcg Aluminum
- PC (Pneumococcal) Vaccine – 125 mcg Aluminum
- DTaP – Taptacel Brand (Sanofi Pasteur) – 330 mcg Aluminum
- DTaP – Tripedia Brand (Sanofi Pasteur) – 170 mcg Aluminum
- DTap – Infanrix Brand (GlaxoSMithKline) – 625 mcg Aluminum
- DT (Sanofi Pasteur) – 170 mcg Aluminum
- dT – Decavac (Sanofi Pasteur) – 280 mcg Aluminum
- Heb P – Recombivax (Merck) – 250 mcg Aluminum
- Hep B – Engerix-B (GlaxoSMithKline) – 250 mcg Aluminum
- Hepatitis A – 250 mcg Aluminum
- HPV – Gardasil – 225 mcg Aluminum
- Comvax (hep B and HIB) – 225 mcg Aluminum
- Pentacel (DTaP, HIB and Polio) – 330 mcg Aluminum
In other words, a newborn who gets a Hepatitis B injection on day one of life would receive 250 mcg of aluminum. This would be repeated at one month with the next Hep B shot. When, at two months, a baby gets its first big round of shots, the total dose of aluminum could vary from 295 mcg (if a non-aluminum HIB and the lowest-aluminum brand of DTaP are used) to a whopping 1225 mcg (if the Hep B vaccine is given along with the brands with the highest aluminum contents). These doses are repeated at four and six months. With most subsequent rounds of shots, a child would continue to get some aluminum throughout the first two years. But the FDA recommends that premature babies, and anyone with impaired kidney function, receive no more than 10 to 25 mcg of injected aluminum at any one time. Source: The Vaccine Book, Dr. Bob Sears
BLAYLOCK: In fact aluminum has been well studied and shown to be a specific neurotoxin. Like mercury, it activates microglia (the immune cells of the brain) and induces immuno-excitotoxicity. It also accumulates in the brain and a study has been done in which aluminum adjuvants in vaccines were radio-labeled and shown to accumulate in a number of organs including the brain. When doctors give 7 vaccines at one sitting they are giving the child seven doses of aluminum adjuvant—so we have the immune over-activity/microglia effects as well as the direct toxicity of the aluminum that accumulate in the brain—but then he would not know that since he knows nothing of neuroscience.
The fact that he and others are willing to expose millions of children to vaccines that can cause problems-- not weeks after, but months and even decade after they are given—is frightening.
Yet, they recommend these vaccines for the immuno-compromised. He also ignores the fact that attenuated viruses can become pathogenic once more when harbored in the body as discussed earlier. As for bacterial vaccines, they can suppress immunity—as seen with the HiB vaccine (The insert warns of increased risk of Hibs meningitis for two to three weeks after the vaccine) Also, the MMR vaccine (measles and rubella viruses) are powerfully immunosuppressive and leaves the child susceptible to a great number of other viral and bacterial infections during that time. No one bothers to tell mothers that—especially those putting their children in daycare centers.
I do not necessarily condemn him for making a profit off a product—it is his arrogance in attacking everyone who might endanger his product. When he served on the board of ACIP [Advisory Committee on Immunization Practices at the CDC] he did not recuse himself because of his conflict of interest. What really upsets me is his arrogance and his personal attacks on anyone who questions the safety of the vaccine schedule or implies that vaccines might not be safe.
He is in no position, based on his own admission of having a lack of knowledge of neurology, neuroscience and toxicology, to make any demands on others seeking legitimate answers. He also demonstrates an abysmal lack of knowledge of immune system function as well. This interview clearly demonstrated that he is on shaky ground.