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New Study: Many Cases of Infantile Autism may Actually be Induced by Acetaminophen exposure shortly after birth

Infant tylenolNOTE: Can you think of a product more fraught with injury? From the poisoning scandal decades ago, to heavy metal pieces found in the product, to the actual usage causing a cascade of chemical changes linked to autism.  One day, Tylenol will be viewed like Thalidomide. Soon, we hope.

Jennifer Margulis, co-author of The Vaccine Friendly Plan with Dr. Paul Thomas posted this on Vaccine Friendly PlanFacebook: 

Breaking news: A team of researchers from Duke University School of Medicine and Harvard University have just this morning published a comprehensive review article in the peer-reviewed JOURNAL OF INTERNATIONAL MEDICINE showing scientifically how acetaminophen is a MAJOR FACTOR in DAMAGING CHILDREN'S BRAINS.

"The use of acetaminophen in babies and young children may be much more strongly associated with autism than its use during pregnancy, perhaps because of well-known deficiencies in the metabolic breakdown of pharmaceuticals during early development. Thus, one explanation for the increased prevalence of autism is that increased exposure to acetaminophen, exacerbated by inflammation and oxidative stress, is neurotoxic in babies and small children. This view mandates extreme urgency in probing the long-term effects of acetaminophen use in babies and the possibility that many cases of infantile autism may actually be induced by acetaminophen exposure shortly after birth," the 9 scientists write.

Please take the time to READ this study and SHARE it with your doctor, nurse practitioner, hospital worker, or other healthcare provider. And please tag any JOURNALISTS you know and encourage them to write about it: http://journals.sagepub.com/doi/pdf/10.1177/0300060517693423

ABSTRACT

The wide range of factors associated with the induction of autism is invariably linked with either inflammation or oxidative stress, and sometimes both. The use of acetaminophen in babies and young children may be much more strongly associated with autism than its use during pregnancy, perhaps because of well-known deficiencies in the metabolic breakdown of pharmaceuticals during early development. Thus, one explanation for the increased prevalence of autism is that increased exposure to acetaminophen, exacerbated by inflammation and oxidative stress, is neurotoxic in babies and small children. This view mandates extreme urgency in probing the long-term effects of acetaminophen use in babies and the possibility that many cases of infantile autism may actually be induced by acetaminophen exposure shortly after birth

Comments

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Alexandra

My son was also born in 2001 and I too followed the advice to give Tylenol right before vaccines.

My husband and I got educated on vaccines when he was four. Our son hasn't had a vaccine since the age of 2.

Since then, my son has very seldom had any Tylenol. If he has a cold he gets coconut oil and apple cider vinegar mixed in a drink.

Carolyn M

My son was born in 2001. At that time we told to give the Tylenol before going to get the shots. We were also told when he had a fever to alternate tykenol with Motrin in a way that allowed you to "safely" have both. So add that in with all the shots ...

John Stone

Britsh Autism Mother

Slightly mystified by the conversation - I think Calpol is the British equivalent of infant or children's Tylenol ie the product marketed by Johnson & Johnson, MacNeil etc. whereas the Panadol brand for the same substance (acetaminophen or paracetamol) is owned by GSK. There seem to be infants and children's version as well, but the products are still available, although oddly not as familiar as Calpol as a brand name in recent times. No doubt they are dressed up in very similar gunge as well.

I was just looking at the Calpol website and they were recommending if for dealing with the newly added Bexsero Men B vaccine on the UK vaccine schedule. Yuck.

British Autism Mother

In 1991 one of my fraternal twins was teething so fractious. The health visitor's instruction was to give a small dose of Calpol (pink paracetamol goo). Within minutes that tired, fractious baby was revived, no longer tired and could have been saying "hey, Mum, where's the party?" When I informed the health visitor of the reaction she said "Oh! That's the E122 (pink colouring). Use Panadol instead." I understand the formulation for Calpol was changed later, however Panadol was taken off the market about the mid-nineties.

david m burd

@ Andy McGregor,

You cite references 122,123 showing "unvaccinated" kids still developed autism. In fact, the one study (123) by Jain, Marshall, Buikema did document such kids WERE actually vaccinated and compared to their older siblings; further what they compared were the relative RATES of autism.

Finally, this 123 study was funded by NIH and HHS, who have dogmatic resistance to ever admitting vaccine damage. The other Study 122, if I recall correctly, only studied about 100 children - far too few as to ascertaining definitive conclusions.

You stand "false impression by parents" on its head, telling stricken parents they should not believe what they actually experienced seeing their babies and children lose their health immediately following vaccinations, and following idiotic doctors' instructions to then dose their kids with Tylenol.

David Foster

Mr McGreggor,

What is interesting to me is that both you and the authors of this acetaminophen study seem to protest too much. I never even mentioned vaccines, so I'm not sure why your rambling on about it. I do see the authors don't feel that vaccines cause autism...I also see that these authors don't seem to know a whole lot about this issue, especially about ethyl mercury and aluminum adjuvants. They cite an article to deny that mercury causes autism, yet that study was specifically about an H1N1 flu vaccine. They claim that this vaccine caused a neuropsychiatric condition (narcolepsy), and note that this vaccine does not contain mercury or other metals so therefore these metals must not be related to autism. Wait. What??

Not only is their logic ridiculous, but they are incorrect. The vaccine which caused narcolepsy did in fact contain mercury:

http://www.who.int/immunization_standards/vaccine_quality/Pandemrix_Package_Insert.pdf

"This vaccine contains thiomersal as a preservati e and it is possible that you may experience an allergic reaction."

Also, I'm not sure they really should be even bringing this to our attention since this vaccine caused an autoimmune reaction which caused brain damage. So there is that.

I was simply sharing this study because I've seen earlier preliminary work which suggests that acitaminophen may be a risk factor for autism, so I thought this was interesting.

So I'm not sure why you are starting your own little argument, and being quite the jerk in the process. If you want to disagree with something I've said that's perfectly fine, I love to argue. But there is no need for ad hominem attacks against me.

no-vac

I caution against believing Cuba's medical info. Cuba is a very poor country which certainly cannot afford expensive multiple vaccinations. As the link from WHO below shows, their data on infectious diseases are totally fabricated, as they report none. It would be necessary to speak openly to Cuban parents and physicians to get reliable info on vaccine use. IMO in Cuba autism rate is low, because they use very few and their own vaccines, not the western poisons produced in China.
http://apps.who.int/immunization_monitoring/globalsummary/countries?countrycriteria%5Bcountry%5D%5B%5D=CUB

John Stone

Mr McGregor,

I have no idea what David said but it is interesting how someone like yourself posing at being a scientist uses ad hominem insults as their main weapon - this is repulsive and nauseating behaviour (and anti-scientific). This is a paper arguing that acetaminophen may be implicated in autism - it is not a new hypothesis nor I believe the only paper which has suggested this. One obvious point is that if vaccines induce fever and are given increasing quantites to infants and acetaminophen is the first line of treatment then this would be a very stupid cycle. A logical error in this article, however, is that there is necessarily a single agent inducing autism, as opposed, say, to bombarding an infant with a multiplicity of fever inducing agents and toxins, and then using acetaminophen to douse the local effects, or that given these extraodinary and lunatic practices that there is any simple way to unravel how damage is caused. Very often even papers published as scientific contain incredible solecisms.

Another oddity is that in dismissing the thimerosal/autism hypothesis Parker et al cite a paper about narcolepsy with no clue as how it addresses this question, if at all - certainly the abstract is no help.

Perhaps, the reference should have been to note 121, the paper by Hviid. Here we should note the published comments of Bernard Rimland and Sallie Bernard and the absence of any reply:

http://jamanetwork.com/journals/jama/article-abstract/197969

Linda1

"I would not even caution people against the use of acetaminophen in babies - I would expect medical authorities to weigh the evidence and come up with guidance for physicians. "

This is why there is an out of control skyrocketing autism epidemic. Let's just keep doing what we're doing until there are no healthy children left. Good advice.

Andy McGregor

Thank you David Foster for alerting me to this study. I am pleased you approve it because it states that there is no link between vaccination and autism. I have pasted below the full text of the relevant part of the paper which may explain why non-scientists like David Foster hold such unscientific beliefs.

For those who do not have time to read to the bottom, the relevant line is "may have given many parents the false impression that their child’s autism was induced by a vaccine."

Yes, those who think Vaccination and Autism are linked have a "FALSE IMPRESSION"

For non scientists, this paper does not prove a link between a commonly used analgesic and Autism. What it does is propose that there could be a link and that more study is needed. This paper seeks to justify further work, that is all. The personal action I would take is caution - I would not even caution people against the use of acetaminophen in babies - I would expect medical authorities to weigh the evidence and come up with guidance for physicians. I would certainly not race off to lawyers asking them to make claims or produce a misleading video making sensational claims which mislead parents into putting their children at risk of death or permanent injury!
---------------------------------------------------------------------------------------------
(From pages 10 and 11 - The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism)

Proposed triggers of the autism epidemic: Ethyl mercury and vaccines

The view that vaccines and ethyl mercury in particular, a component of the preservative thimerosal used in some vaccines, can induce the development of autism is widespread among non-scientists 115,116 and has been discussed widely in the literature.117,118. Proposed mechanisms of induction depend on the difference between methyl and ethyl mercury119 to account for the relatively recent rise of autism compared with the centuries-old use of methyl mercury.

However, a study addressing this issue found no association between levels of mercury exposure during vaccination and the incidence of autism 120. Further, a substantial reduction in exposure to ethyl mercury as a result of elimination of thimerosal from vaccines has not reduced the rate of autism. It has been counter-argued that ‘‘no level is safe,’’ suggesting that any amount of ethyl mercury may be dangerous. However, since the induction of autism (by whatever agent) is apparently not near the saturation point (presumably yielding a rate of 100% autism in the population, at which point the rate of autism would be independent of increasing or decreasing levels of inducing agent), then it is expected that a substantial reduction in the amount of inducing agent would lead to at least some reduction in the level of autism. It has been argued that perhaps aluminum adjuvants now replace mercury preservative as the vaccine-associated agent, but then ethyl mercury and aluminum must be different from methyl mercury in some regard, straining the original hypothesis regarding the uniqueness of ethyl mercury. It could be counter-argued that the route of exposure (injection vs. dietary intake) of the metal is important, but in the one widely accepted instance in which a vaccine caused the induction of a neuropsychiatric disorder (narcolepsy with cataplexy), no metal preservatives or metal adjuvants were involved.120 Thus it could be argued that it is the vaccination in general that is critically important, not the metal per se. Yet vaccines are much older in their origins than autism, and it is not intuitive that a vaccine would be worse than an actual life-threatening infection, the origins of which are ancient and pre-date the human race. This view is corroborated by a cohort of parents who did not vaccinate younger siblings of children with autism; failure to vaccinate with one or even all vaccines did not prevent autism.122,123 Most importantly, acetaminophen, the analgesic most commonly administered in conjunction with vaccination and the only analgesic administered to children under the age of 6 months following vaccination, has been identified as a likely inducer of autism.124 Initial studies described below suggest that it is the co-administration of this analgesic with vaccines that may have given many parents the false impression that their child’s autism was induced by a vaccine.

Peakcuriosity

Tylenol-connected liver and glutathione problems are not the only pathway people should be concerned about when it comes to giving it to newborns, or anyone.
Tylenol has antibacterial effects also.
https://www.ncbi.nlm.nih.gov/pubmed/20067876
Title:
"Antibacterial effect of NSAIDS on clinical isolates of urinary tract infection and diabetic foot infection."
Highlights:
" Tylenol has marked effect on pathogens at 100 microg concentration. Aspirin and Tylenol along with analgesic, anti-pyretic, anti-inflammatory properties also have marked anti bacterial effect on isolates from UTI and Diabetic foot infections and inhibits the growth of both gram negative and gram positive bacteria, and both can be used synergistically with antibiotics for effective treatment."
"Bacteria isolated from urine samples were Escherichia coli 30%, Staphylococcus aureus 20%, Enterococcus faecalis 10%, S. saprophyticus 10%, Proteus spp. 6%, Pseudomonas spp. 6%, S. pyogenes 6%, S. agalactiae 6%, S. epidermidis 4%, and Klebsiella spp. 2%. Bacteria isolated from pus samples were S. aureus 30%, Pseudomonas aeruginosa 18%, S. epidermidis 14%, Klebsiella pneumonia 12%, Proteus mirabilis 12%, E. coli 10%, P. vulgaris 4%."
Aspirin, too, had an effect, but at slightly higher dose levels than the tylenol.

That to me means that what little micobiome is trying to form in a newborn, using nsaids after vaccination destroys some of it - then it's in a diminished capacity when the vaccine ingredients start circulating in the blood, brain, tissue, making their way to the gut, which is supposed to help that stuff leave the body, but we've hindered that capacity. With nothing to manage and dispose of the vaccine effluent available, the effluent stays there and destroys the intestinal lining or causes leaky gut - effectively opening the flood gates to recirculating the effluent back into the body. (obviously newborns don't have fiber in their diet yet, the other excretory helper than can bind up toxic environmental effluent and remove it from the gut).

This is in no way suggesting that vaccines are safe and than tylenol is the problem. Tylenol just serves as an acute time-relevent exposure tipping the body's environment toward susceptibility to vaccine injury. Knowing that mercury itself is an antibiotic AND causes leaky gut, that same process can occur regardless of tylenol, just possibly in more slow motion, long term way.

If doctors say that when a person is on antibiotics they should take the entire course in order to avoid cutting short the eradication which could lead to antibiotic resistance, what is short course use of Tylenol doing in regards to contributing to antibiotic resistance and biofilm development?


david m burd

Diane Farr,

Very intriguing about Cuba! Can you be more specific about their "aggressive" vaccine schedule as to the precise vaccines and at what month/year they are administered? Also, are they voluntary? - and what percentage of kids end up being vaccinated? Can parents exempt their children? Thanks!

david m burd

This http below discloses references and large Studies reporting a direct connection between Tylenol (acetaminophen in the U.S., paracetamol in Europe) multiplied factors of damaged infants/children. As others have said, combining toxic fever-causing vaccinations and toxic acetaminophen can logically, exponentially multiply their individual damage potential(s).

http://www.thehealthyhomeeconomist.com/tylenol-just-once-a-month-raises-a-childs-asthma-risk-540/

Diane Farr

I saw an article that talked about how in Cuba acetaminophen has to be prescribed by a doctor. Autism rates are extremely low; although they have an aggressive vaccine schedule. I started thinking about how much acetaminophen is given to babies. Before and after vaccines, teething, fevers, ear aches. I find it suspicious that the timing of aspirin warnings for under the age of 12 coincides with the time when Tylenol was introduced.

Grace Green

no-vac and ATSC, In the 80s when my kids were born, acetaminophen was marketed to juveniles under the name Calpol in the UK. It was recommended for every ache and pain, and no doubt would have been given to many post vaccination. My poor boys just had to suffer, as we still do at the dentist, refusing anaesthetics (see previous article). Maybe it turns out I did the right thing, (apart from the vaccinations of course).

ATSC

no-vac,

"In Europe or Asia acetaminophen is not generally given to infants"

I don't know about the rest of Europe or Asia but it looks like paracetamol or ibuprofen is given to children in the UK if they have a fever after vaccination, and paracetamol is another name for acetominophen:

http://www.nhs.uk/Conditions/vaccinations/Pages/reporting-side-effects.aspx
NHS What to do if your child is unwell after having a vaccination

"You can also give them a dose of infant paracetamol or ibuprofen liquid according to the instructions on the bottle. "

no-vac

In US acetaminophen after birth is given to infants to reduce pain and fever associated with toxic vaccinations. There is no other reason to give it to majority of babies. Hence it is difficult if not impossible to dissociate the effects of vaccines and acetaminophen. In Europe or Asia acetaminophen is not generally given to infants, as it is considered toxic, but still millions of children become autistic after vaccinations. IMO, vaccines are the primary culprit while acetaminophen may enhance vaccine toxicity. Likely, babies given two toxins, vaccines + acetaminophen, are more severely damaged than those receiving vaccines only.

Someone

@ Bob:
Just wanted to let you know that the shingles vaccine lawsuit won't be decided by the dreaded kangaroo court special masters, because injuries due to the Zostavax vaccine apparently aren't covered by the National Vaccine Injury Compensation Program.
https://www.hrsa.gov/vaccinecompensation/coveredvaccines/index.html

whyser

The metabolism of acetamenophen releases a toxic compound called NAPQI (N-acetyl-p-benzoquinone imine). Just as LISA has said earlier, it depletes glutathione stores (mostly in the liver), because glutathione is required to neutralize that toxin.

LISA also stated that depleted glutathione is not a big problem by itself, but I would slightly disagree. Although mercury is mostly removed from the majority of vaccines, all vaccines, by nature, are sources of chronic, low-grade, oxidative stress. One of the most common vaccine reactions is to react with inflammation and fever, and most doctors and parents are under the impression that any discomfort, like fevers, must be immediately remedied by... tylenol.

Too often on forums do I see parents mindlessly administer tylenol after a vaccine appointment.
Too often do I see parents giving more and more tylenol when the fever doesn't go DOWN.

A baby is having an inflammatory response which produces a lot of ROS (Reactive Oxygen Species) due to an increase in cellular respiration to induce that reponse, they'll need all the glutathione they can get. They'll need more glutathione to deal with the damage that is being purposefully induced by the vaccine in order for it to stimulate the immune response. AND they need even more glutathione to deal with the NAPQI toxic byproduct that is released from tylenol.

How is this NOT a recipe for increased risk in autism when we all know that autism is highly correlated to significant oxidative stress??

Benedetta

I sure was told to load up with Tylenol the night of the big third DPT shot .

I was also told to load up - over the recommended dose - way over; again my children's very dangerous pediatricians when ever my son had a fever --- that was after the DPT reaction and we were having seizures.

It is just febrile seizures they said.
Well his first two big bad seizures within the scope of 8 months after the DPT vaccine was associated with fever spikes. That is because the DPT vaccine was still lurking within his little body upping the inflammation; not unlike juvenile rheumatoid arthritis; that my dear little cousin had at age five years old.

Then after that there was the strange monthly periodical fevers lasting a week.
I think I might have saved what was left of my son's brain by switching to aspirin, during these strange episodes that the peds always claimed was a virus, it will pass. None every did. We would wait three days and go back and then get antibiotics, because it turned into pneumonia, or severe ear infections.

Fast forward to 2017; and for younger mothers it is worse, far worse. I still have not got over it all yet and it is just worse. CDC they burned down our houses, our homes, our dreams, and our hopes.
.

Lisa

Acetaminophen depletes glutathione. Glutathione is needed to remove mercury from the body. Temporarily depleted glutathione likely is not a big problem by itself. It becomes a very big problem when it happens at the same time a baby is injected with mercury. Thus, it likely is not acetaminophen by itself but rather in COMBINATION with vaccination, which so commonly occurs, that creates the association with autism.

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