Great comment from John Gilmore of Autism Action Network on NY Times story on DSM-V: "This is to be expected from the Times. If anything the New York Times sees itself as the stentorian voice of the secular credentialed elites....
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AofA Science Summary: Do Childhood Mumps Protect Against Ovarian Cancer?
Cancer Causes Control. Author manuscript; available in PMC 2011 August 1.
Published in final edited form as:
Cancer Causes Control. 2010 August; 21(8): 1193–1201.
Published online 2010 June 18. doi: 10.1007/s10552-010-9546-1
Background
Epidemiologic studies found childhood mumps might protect against ovarian cancer. To explain this association, we investigated whether mumps might engender immunity to ovarian cancer through antibodies against the cancer-associated antigen MUC1 abnormally expressed in the inflamed parotid gland.
Methods
Through various health agencies, we obtained sera from 161 cases with mumps parotitis. Sera were obtained from 194 healthy controls. We used an ELISA to measure anti-MUC1 antibodies and electro-chemiluminescence assays to measure MUC1 and CA 125. Log-transformed measurements were analyzed by t-tests, generalized linear models, and Pearson or Spearman correlations. We also conducted a meta-analysis of all published studies regarding mumps and ovarian cancer.
Results
Adjusting for assay batch, age, and sex, the level of anti-MUC1 antibodies was significantly higher in mumps cases compared to controls (p = 0.002). Free circulating levels of CA 125, but not MUC1, were also higher in cases (p = 0.02). From the meta-analysis, the pooled odds ratio estimate (and 95% CI) for the mumps and ovarian cancer association was 0.81 (0.68–0.96) (p = 0.01).
Conclusion
Mumps
parotitis may lead to expression and immune recognition of a
tumor-associated form of MUC1 and create effective immune surveillance
of ovarian cancer cells that express this form of MUC1.
Read the full abstract at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951028/.
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Mumps, an anti-cancer vaccine? Kind of ironic that in vaccinating for mumps we may be "training" the immune system to avoid cancer-fighting training.
Posted by: Jeannette Bishop | September 18, 2012 at 01:23 PM
So having mumps around helps in preventing ovarian cancer
chicken poxs helps in preventing shingles.
Posted by: Benedetta | September 18, 2012 at 10:49 AM