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Mercury Leaves Its Mark: Autism, Cancer & Neurodegenerative Disease Part 1

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By Teresa Conrick

Having a daughter who regressed into autism compels me to research medical journals because she began having health complications after vaccinations.  I have an insatiable hunger for knowledge about mitochondrial dysfunction, inflammatory responses (brain and gut), oxidative stress, immune abnormalities, and hormonal dysfunction causing seizures.  Cancer was really not on my radar too much but it has crept up more as Megan's estrogen levels now make her a prime candidate for it, especially breast cancer.  You can read about her horrific hormone levels as a causative factor in her catamenial epilepsy HERE.  Cancer can be considered a "regression" in healthy cells, most likely due to an environmental cause, yet we don't always hear that.

In a related search last year, I began to examine and write about melanin, and my thoughts about its involvement in autism.  It seemed to me that there was a peculiar propensity for an autism diagnosis in those who had red hair, light eyes or just more of a fair complexion, ie - less melanin.  Tyrosine, an amino acid needed to make melanin, seemed somehow tied up but I wasn't sure how.  Much research backed up the idea that having less melanin did make one more vulnerable to other "neuroregressive" disorders such as ALS, Parkinson's, Alzheimer's, and Schizophrenia, but also Melanoma.  Add Melanoma as another Megan health concern I have because she is just so fair, and seems to contain the recipe for these environmental attacks.  What brought me closer to these concerns is that by looking at the similarities of these diseases, one can see the pattern emerge.  I saw that as I began to look not only at the symptoms but also at the pharmaceutical management - ie - medications being used or contemplated.  The first clue was that there seemd to be some pigmentary disorders in children who also happen to have an autism diagnosis.  Is that a coincidence or is that showing a mechanism of what may be happening behind the scenes of this historically misunderstood disorder? I hope I can unfold this pattern here so that it can be looked at for further research.  It seems that medicine too often develops a pill to treat a symptom while not searching for the roots to the actual diseases and illnesses.  Since autism has become a disorder that is increasing at alarming numbers, and with much physical and emotional suffering, it is our duty as a moral and ethical nation to find both cause and cure.

Recently, as I was reading about each - melanin, autism and cancer - certain websites and words kept reappearing - the puzzle pieces were emerging. One of those pieces that I kept running into was medication, initially FDA approved for neurodegenerative conditions, yet interestingly, one was now being considered for use in breast cancer. Since the two seem completely unrelated as diseases, I was intrigued. Now what makes that more compelling is that the same pharmaceutical medication is now being looked at for autism.  The key factor that the drugs are working on for each of these diseases are the mGluR, Metabotropic Glutamate Receptors. I wrote about them HERE as many were racing to find a cure with drugs targeting these receptors but hardly any of them seemed to care about the causation or WHY they were implicated.  Now cancer is another race for the cure with these glutamate receptors but how is it related to autism?  Here was a study that could answer that question:

"Methylmercury Increases N-Methyl-d-Aspartate Receptors On Human SH-SY 5Y Neuroblastoma Cells Leading To Neurotoxicity" 2008  (HERE)

"Methylmercury (MeHg) is a known neurotoxin, yet the mechanism for low dose chronic toxicity is still not clear. While N-methyl-D-aspartate receptors (NMDARs) were found to be induced after exposure to MeHg in a mink model, its role on neurotoxicity is not known. The aims of this study were to investigate the expression and the functional roles of NMDARs on the induction of cell death in the human SH-SY 5Y neuroblastoma cell line after exposure to MeHg. We found a significant increase in NMDARs followed by increased caspase-3 activity after 4 h of exposure to MeHg (0.25-1 microM). Necrotic cell death was found after 4 and 24 h of exposure to MeHg (0.25-5 microM). The NMDAR antagonists dizocilpine ((+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-iminemaleate [(+)-MK801]) and Memantine (1-amino-3,5-dimethyl-adamantane) (10 microM) completely attenuated MeHg-mediated cell death by blocking NMDARs, thus demonstrating the importance of NMDARs in mercury neurotoxicity.

Two things of importance from that study:  1- From Wikipedia -  "Metabotropic glutamate receptors are known to act as modulators of (affect the activity of) other receptors. For example, group I mGluRs are known to increase the activity of N-Methyl-d-Aspartate Receptors (NMDARs), a type of ion channel-linked receptor that is central in a neurotoxic process called excititoxicity."---- meaning that mercury is shown here to be CAUSATIVE to the " (NMDARs) were found to be induced after exposure to MeHg" and 2- Memantine is one of these drugs being used for neurological, regressive diseases and also being investigated for Autism: OSU Medical Center

That seems pertinent on many levels.  Some caveats: A significant increase in NMDAR's after exposure to mercury.  Memantine weakened that effect by blocking the NMDAR's. The NMDAR's are important in mercury neurotoxicity.

From Wikipedia: Memantine is the first in a novel class of Alzheimer's Disease medications acting on the glutametergic system by blocking NMDA glutamate receptors. It was first synthesized by Eli Lilly and Company in 1968. Memantine is marketed under the brands Axura and Akatinol by Merz, Namenda by Forest, Ebixa and Abixa by Lundbeck and Memox by Unipharm.

Very interesting connections. Here too, is another study but this one describes Riluzole's effects on mercury.  Remember, Riluzole was first introduced as a drug to treat ALS and according to the ALS Association , "Riluzole, the first treatment to alter the course of ALS, was approved by the FDA in late 1995. This antiglutamate drug was shown scientifically to prolong the life of persons with ALS by at least a few months. More recent studies suggest Riluzole slows the progress of ALS, allowing the patient more time in the higher functioning states when their function is less affected by ALS. Rilutek® (Riluzole) is manufactured by Sanofi-Aventis Pharmaceuticals, who sponsor a Patient Assistance Program that helps patients who qualify receive the drug." An internet search shows the price of Riluzole to be about $9 a pill.

Journal of Environmental Health, 2010 "Antagonism of Dextromethorphan and Riluzole to Neurotoxicity Induced by Methylmercury in Rats" 


"Objective- To observe the adverse effect of methylmercury on the cortex and cerebellum respectively as well as to approach the antagonisms of dextromethorphan(DM) and riluzole to the mercury-induced neurotoxicity...Conclusion "Glu-Gln Cycle" can be destroyed by MMC ( methylmercuric chloride).  DM and Riluzole present some antagonistic effects on MMC-induced neurotoxicity in rats."

The fact that these drugs target glutamate dysfunction and then research shows that these same drugs are shown to stop MERCURY-INDUCED NMDA NEUROTOXICITY,  well, it appears that correlation and causation sure seem to fit. So how is cancer related to that?  It looks like a similar pathway with similar causation.   Last year, I posted research that linked mercury exposure to melanoma. Here it is again as it seems to make sense as we discuss melanin, NMDA receptors and mercury exposure:

"Skin Cancer" by Keyvan Nouri - 2007
"Metal exposure may be quite important in the development of melanoma and has been very little studied. Occupational arsenic and mercury exposure have been associated with an increased risk for cutaneous melanoma among Swedish women who were members of an occupational cohort."
"Cutaneous melanoma in Swedish women: Occupational risks by anatomic site."
"Accordingly, our aim was to identify occupations with higher risk of cutaneous melanoma, overall and by site, in Swedish female workers. RESULTS: High risks were observed among educators, bank tellers, dental nurses, librarians/archivists/curators, horticultural workers, and hatmakers/milliners. Some occupations with possible exposure to arsenic/mercury displayed increased risk."

Well, in an interesting exchange directed towards our own Jake Crosby, who wrote about Dr.David Gorski  Age of Autism Financial Ties  , cancer doctor and now head of a clinical investigation into Riluzole for breast cancer: "Official Title: Metabotropic Glutamate Receptor-1 (mGluR1): Validation of a Serendipitously Discovered Molecular Target for Breast Cancer Treatment" ClinicalTrials.gov

"The reason Jake mentioned Riluzole is because it’s one drug I study as a potential therapy for breast cancer. In fact, if I do say so myself, the project looking at Riluzole in breast cancer is an example of why science-based medicine is so cool compared to the fairy dust of “alternative” medicine or the pseudoscience that is the anti-vaccine movement. It all began a while back with a basic scientist at Rutgers named Suzie Chen, who wanted to make a transgenic mouse to study adipogenesis. So she used standard techniques to insert a gene she wanted to study, but after the transgenic mice were born the mice in one of the strains all developed skin lesions that looked like melanoma by the age of two to four months. Being a good and careful scientist, Dr. Chen realize that she had inadvertently created something really interesting, a mouse model of melanoma. So, teaming up with Dr. James Goydos, my surgical partner at The Cancer Institute of New Jersey (which is where I was at the time), Dr. Chen went back and looked at what had happened and figured out that the transgene had disrupted part of the regulatory region of a gene known as Grm1 (GRM1 in the human), which codes for a gene known as metabotropic glutamate receptor-1 (mGluR1), in such a manner that mGluR1 was being made at a level far higher than normal."

"A word of explanation is in order here. Glutamate is a major neurotransmitter in mammals that functions by binding to either ionotropic or metabotropic receptors (genes: GRM1-GRM8; receptors: mGluR1-mGluR8). I’m not going to talk about ionotropic  glutamate receptors. mGluRs belong to a family of G-protein-coupled seven transmembrane domain receptors (GPCRs), which mediate responses to a diverse array of signaling molecules, including hormones, neurotransmitters, chemokines, and autocrine and paracrine factors. In the mammalian CNS, mGluRs, which are categorized into either group I, II, or III receptors based on   sequence, what compounds they bind, and how they signal in the cell, are essential for normal neuronal function, and have been implicated in diverse neurological pathology, particularly ALS. Their existence and importance in melanoma had previously been  unsuspected." 


Another point made by Dr. Chen in a different interview was that "melanoma cells release a lot of a substance called glutamate."  I think that is worth mentioning as it relates back to the melanin implications of these diseases.

The irony and Serendipitously Discovered realization that cancer and here, breast cancer, as also having roots with glutamate receptors is just so strange.  I am eternally hopeful that breast cancer will be cured and I'm all for research but the search for medications seems more of a money-maker than a true medical breakthrough in the abolishment of disease.  Dr. David Gorski, who incessantly ridicules parents for looking at both cause and cure to autism and especially concern about vaccines and mercury/thimerosal, has never discussed the issue of glutamate dysfunction in autism nor the strong correlation to mercury exposure.  His glaring disdain for the topic of mercury induced illness in children vaccinated, who then develop symptoms of autism, has always been mystifying and hardly scientific. Here was Dr.Gorski just eight months ago regarding autism and mercury: "Two and a half years ago, very early in the history of this blog, I wrote one of my usual logorrheic (although I prefer the word “comprehensive”) posts entitled, "Mercury in Vaccines as a cause of autism and autism and autism spectrum disorders )ASDs): A failed hypothesis. In that post, I characterized the scientifically discredited notion that the mercury in the thimerosal preservative that used to be in several childhood vaccines was the cause of the “autism epidemic” as “one of the most pernicious medical myths of recent years.” And so it is." 

In 1998, Wayne University, where David Gorski is currently doing the Riluzole Clinical Trial, did a study that seems related to this topic:
"Low levels of ionic mercury modulate protein tyrosine phosphorylation in lymphocytes"

"The ability of ionic mercury to induce protein tyrosine phosphorylation in mouse spleen cells and in the mouse WEHI-231 B-cell lymphoma was investigated. We have confirmed previous studies which showed that exposure to high levels (several hundred microM) of mercury lead to very large increases in the level of protein tyrosine phosphorylation in these cell systems. However we have also demonstrated that low levels (in the order of 0.1 to 1.0 microM) of mercury also significantly upregulate protein tyrosine phosphorylation. Mercury induced protein tyrosine phosphorylation is inhibited by the mercury chelator penicillamine and by pretreating treating target cells with the sulfhydryl blocking reagent N-hydroxymaleimide. These results suggest that exposure to low levels of mercury could potentially interfere with lymphocyte signal transduction and so offer a possible explanation as to how mercury exposure could lead to immune cellular dysfunction. On a molecular level, the results suggest that the site(s) of action with respect to mercury dependent induction of protein tyrosine phosphorylation is likely a free disulfide group or groups located on the outer leaflet of the plasma membrane."


Here is a brief description of protein tyrosine phosphorylation:   Recent research shows that protein tyrosine phosphorylation (tyrosine kinases) are important mediators of the signaling cascade, determining key roles in diverse biological processes like growth, differentiation, metabolism and apoptosis in response to external and internal stimuli. Recent advances have implicated the role of tyrosine kinases in the pathophysiology of cancer. Tyrosine phosphorylation is a reversible, dynamic process controlled by the activities of the protein tyrosine kinases (PTKs) and the competing actions of the protein tyrosine phosphatases (PTPs).
 
Here was that word, "tyrosine" along with the word "chelator"and maybe now I could see how it may fit into this connection of mercury to NMDA receptors:
"Stimulation of protein tyrosine phosphorylation by NMDA receptor activation" 1991 HERE
"The N-methyl-D-aspartate (NMDA) receptor, a subtype of glutamate receptors, plays a key role in synaptic plasticity in the nervous system. After NMDA receptor activation, calcium entry into the postsynaptic neuron is a critical initial event. However, the subsequent mechanisms by which the NMDA receptor signal is processed are incompletely understood......Stimulation of cultured rat hippocampal cells with glutamate resulted in the rapid and transient tyrosine phosphorylation...."


It seems there is a process here and mercury can start the signalling: HERE , 2004 "Results demonstrated that low, noncytotoxic doses of metals induce tyrosine phosphorylation"
 
 
And  HERE,  2008  "Exposure to environmental heavy metals has been reported to affect the immune system. Here, we tested the hypothesis that Hg+2, acting through membrane proteins, disrupts metabolic dynamics and downstream cell functions in human neutrophils. We found that HgCl2 inhibited: (1) polarization and (2) immunoglobulin (Ig)G-mediated phagocytosis of sheep erythrocytes in a dose-dependent manner from 2.5 to 10 µm. Because these activities have been linked with pro-inflammatory signalling, we also studied the effects of HgCl2 on intracellular signalling by measuring protein tyrosine phosphorylation. HgCl2 at doses = 1 µm increased tyrosine phosphorylation."
 
Now here is Thimerosal, the vaccine mercury: HERE  2002 "Thimerosal stimulates focal adhesion kinase and cytoskeletal changes by redox modulation"

In the present study, we showed that HeLa S cells treated by thimerosal generated reactive oxygen species (ROS). Thimerosal-generated ROS stimulated the tyrosine phosphorylation of focal adhesion kinase (FAK) and also induced cytoskeletal changes. Pretreatment with intracellular calcium chelator, BAPTA did not block the thimerosal-mediated FAK tyrosine phosphorylation. On the other hand, either FAK inhibitor, tyrphostin or ROS scavenger, N-acetyl-L-cysteine (NAC) suppressed the tyrosine phosphorylation and cytoskeletal changes. These results suggest that thimerosal seems to induce FAK tyrosine phosphorylation and cytoskeletal changes by ROS generation but not by intracellular calcium mobilization.
 
That process sure seems related to this downstream signalling:

"Phosphorylation of focal adhesion kinase promotes extravasation of breast cancer cells"  HERE

"Inhibition of focal adhesion kinase (FAK) delays transendothelial migration of breast cancer cells...These findings suggest that modified signaling mechanisms regulate cancer cell migration."

Dr. Gorski has mentioned " the role of glutamate receptors in promoting the growth and metastasis of breast cancer" as well as "it’s amazing that we have been able to do as well as we have with various forms of “targeted” therapy directed at specific single molecular targets or a class of molecular targets in cancer cells. Gleevec®, for instance, has been amazingly successful as a targeted agent directed against several members of a class of enzyme known as a tyrosine kinases" in a blog about, "Why haven’t we cured cancer yet?." Perplexing that no where does he mention that Thimerosal/mercury can cause phosphorylation of focal adhesion kinase and that process promotes extravasation of breast cancer cells or at the very least, that  there is "a compelling case for a role for FAK in the pathology of human cancer." HERE
Ignoring cause to race for a cure?

With Sanofi and also Bayer funding him for research, it will be interesting to see what the outcome will be.  Ironically, Sanofi makes flu vaccines today that contain 25 mcg of Thimerosal.  In January, it was reported that "government officials are looking into reports of seizures in patients who'd been given the Sanofi-Aventis influenza vaccine Fluzone. The reports mostly involved children younger than 2--36 of the 42 cases, to be precise--and 10 of the cases were serious, Reuters reports. Thirty-eight of the febrile seizures happened within a day of the Fluzone vaccine."  Sanofi's response -- "Adverse events after vaccination may be causally related to vaccine or may be coincidental."  CDC's response -- "There's no proof of a causal link--as Reuters points out, just because something happens soon after a vaccine is administered doesn't necessarily mean the vaccine caused it." HERE

Bayer had a long history of using 10.5 mcg Thimerosal in each of its Rhogam injections ( 2-3 injections usually per pregnancy) , a human gamma globulin (antibodies) directed against the Rh positive factor of blood. It is given to Rh negative mothers who give birth to Rh positive babies. HERE

I knew the word "phosphorylation" was familiar from a few years back with another redhead: "Autistic spectrum disorders can be associated with mitochondrial dysfunction. We present a singleton case of developmental regression and oxidative phosphorylation disorder in a 19-month-old girl."
"Developmental Regression and Mitochondrial Dysfunction in a Child With Autism"   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536523/    I'll conclude Part 1 with that in mind:

 "Identification of tyrosine-phosphorylated proteins of the mitochondrial oxidative phosphorylation machinery" 2005 http://www.ncbi.nlm.nih.gov/pubmed/15924266

  "The role of some serine/threonine kinases in the regulation of mitochondrial physiology is now well established, but little is known about mitochondrial tyrosine kinases....... Our results suggest that tyrosine kinases and phosphatases are involved in the regulation of oxidative phosphorylation."

Comments

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Organomercury compounds have a huge effect with NMDA on humans and it is difficult to do testing as the cells involved die from these chemicals at very low levels.

It is likely that this is one biochemical pathway contributing to the illness of autism.

At the levels set by the EPA for mercury exposure we get more than 90 per cent death rate.

At lower levels it is certain the blocking of calcium channels in very young infants is causing the epidemic of autism.

Humans are only vaguely aware of how our memory system works and the chemical pathways involved.

It is certain thimerosal injections destroy the normal build up of memory in infants.

One in a hundred clinically showing autism but affecting all those injected even adults to some degree.

See work by Rossi et al on mercury and NMDA.

Knowledge of mercury harm goes back 2 000 years - known to take away our minds.

But also see science 1992 Ronnback chronic encephalopathy induced by mercury.

Effects on calcium channels are irreversible and so an early thimerosal injection can have consequences years later.

Not so much experimenting with thimerosal injections as having callous disregard for infant health.

Russians abandoned thimerosal injections 40 years ago proven in 1972 and earlier as dangerously toxic.

Thanks, everyone for the great comments! This is a series and I hope to get even more of the facts nailed down as we go.


Thanks Benedetta for answering about the CoQ10. You sound like an expert and the quote -- "like pouring water on a burnt out building" -- seems to be a good visual.

Doug
Also best to take it with fish oil, it is oil soluable.

Doug Stables;
My husband has the mitrochondrial cytopathy and they-- the actual medical community - those that have abandon us -- actually had a blood test to decide on the dosage. I don't know what the blood test was called, what they really tested for but he needed 1200mg CoQ10 a day. That comes out about 600 dollars a month way back in the ninties.

I don't know what to think of this supplement. My husband says it is hard to tell, because first of all it probably takes weeks for it to build up in his body. He thinks it works because he ran out of it at one time and then he started feeling really bad. He sure has not been taking that much for a long while (years) because 600 dollars is a hard number to swallow.

I also gave it to my son in a much lower dose, but I was just guessing but 600 a day when my son was in the sixth grade (and start of new school - for all his classmated and himself middle school and change) my son started having seizures (jerks)and in trouble all the time at school. I started giving CoQ10 too him and I can't say everything was better, but about Christmas time things had settle down. The principle told me my son was great and asked what had happened? But it hard to tell, if it was just him getting use to the school or the CoQ10.

Jon Poling the neurologist that won his daughter's vaccine court case by useing the mitrochonrial cytopathy was made worse thing - says that CoQ10 after the damage (vaccine) was too late. It was like pouring water on a burnt out building.

If it works it seems to take mega doses. There is no problem of over dosage from CoQ 10 just going broke doing it.

I have wondered sometimes if there is a possibilty that I could make the darn stuff. They first isolated it from beef hearts - something that slaughter houses don't really know what to do with. Then they started fermenting it from sea weed. Oh well.


Teresa a great article and links,about Mercury and

it's cause of Mitochrondrial Dysfunction,I was

intrigued with your link about D.R.A.M.D in a Child with

Autism, great to see vitamins being effective,I was

very impressed with the child being supplemented with

Co enzyme Q10, at 33 months, would you know please,

what dosage of Q10 was being given, as I have been taking

it myself for nearly 13 years, and it has helped me

enormously,[in the illness I had] and was it Fermented Q10

as it then remains unoxidised, and others that add fillers

binders etc. become oxidised, therfore they lose thier

potency, so be careful where you buy your Q10,

quality Q10 will energise the cellular system,

reverse mitochondria dysfunction [if it's up to standard]

and everything after that is a bonus, hope the child is

improving further.

Dear Teresa, What a coinky-dinky! I was just dealing with a book on the subject of glutamate's role in another illness. Not that I would know a glutamate if I tripped over one. Rather, I was reading this book, called "Killing the Messenger" for other reasons. But as a layperson I venture to guess that you are onto something. I congratulate you.
Here is a link to my Messenger-Killing article, and if I had Mother Teresa Stagliano's email address I would offer the whole article to her for publication at Age of Autism: http://www.rumormillnews.com/cgi-bin/forum.cgi?read=206771

I am very happy that someone mentioned the Burzynski film. This CANCER documentary, I believe, is the most important film about AUTISM you will ever see. Why? It is the story of a doctor in the cancer community that has been "Wakefielded" for almost 40 years, and the story is both utterly compelling and utterly horrifying. I hand out copies of this DVD to people now and say "You don't know what to believe about Wakefield? Watch this." I sure hope Andy Wakefield has seen it. I sure hope Mark Blaxill takes a look and thinks of bringing the cancer community into the Canary Party (because boy have they been screwed). The movie is widely available online, including through Amazon on demand. Please, everyone, take a look at it!


Look like Dr. Manny from Fox News has found the cause of Autism this week.

http://www.foxnews.com/health/2011/06/09/dr-manny-says-autism-breakthrough-is-realfor-now/?test=latestnews


from researchers from Yale, Columbia and Cold Spring Harbor Laboratory......

.......The researchers examined the genomes of more than 1,000 families in which one child was autistic and the siblings and parents were not. Their findings confirmed a .....growing body of evidence..... that autism can be caused by a .....random genetic mutation...... that could occur at .....any one of hundreds of different sites......... in the human genome.


************
Dr. Manny states his son was "born with Autism."

I would assume his son was born & quickly given a heb b shot, on his way to a typical 87x mercury load for his first six months of life....

Dr. Manny / "On behalf of my son, who was born with autism, and my family, I just want to congratulate the men and women who spent years working on this research.....

***********
***********

It is almost beyond amazing that this research has PROVEN that the "mutation of a few base pairs" of DNA, at .....ANY OF HUNDREDS..... of different genetic locations, will cause EXACTLY the same darn thing.... Autism.

but hey, the Science is the Science even if it seems a bit illogical....

"Burzynski, The Movie- Cancer is Serious Business" airing for free viewing on June 11-13, 2001

Watch: http://www.burzynskimovie.com/


ABOUT THE FILM (from movie web site):

Burzynski, the Movie is the (true) story of a medical doctor and Ph.D biochemist named Dr. Stanislaw Burzynski who won the largest, and possibly the most convoluted and intriguing legal battle against the Food & Drug Administration in American history.

His victorious battles with the United States government were centered around Dr. Burzynski's gene-targeted cancer medicines he discovered in the 1970's called Antineoplastons, which have currently completed Phase II FDA-supervised clinical trials in 2009 and could begin the final phase of FDA testing in 2011–barring the ability to raise the required $150 million to fund the final phase of FDA clinical trials.

When Antineoplastons are approved, it will mark the first time in history a single scientist, not a pharmaceutical company, will hold the exclusive patent and distribution rights on a paradigm-shifting medical breakthrough.

Antineoplastons are responsible for curing some of the most incurable forms of terminal cancer. Various cancer survivors are presented in the film who chose these medicines instead of surgery, chemotherapy or radiation - with full disclosure of medical records to support their diagnosis and recovery - as well as systematic (non-anecdotal) FDA-supervised clinical trial data comparing Antineoplastons to other available treatments—which is published within the peer-reviewed medical literature.

One form of cancer - diffuse, intrinsic, childhood brainstem glioma has never before been cured in any scientifically controlled clinical trial in the history of medicine. Antineoplastons hold the first cures in history - dozens of them. [ANP - PubMed 2003] [ANP - PubMed 2006] [Rad & other - PubMed 2008] [Chemo/Rad - PubMed 2005]

Dr. Oz interviews Dr. Stanislaw Burzynski- May 17, 2011

http://www.youtube.com/watch?v=HVejUrKnh6E&feature=youtu.be

Thank you for using your amazing ability to synthesize, elucidate, and make connections to write and share this ! I was reading it thinking "okay this is awesome what can we do now; how do we work with this?"

Question:

Is this relevant to Dr. Amy Holmes work:

http://autism.healingthresholds.com/therapy/glutamate

Teresa, your article is groundbreaking. Just when I thought there was nothing more to be said of David "Orac" Gorski, more is uncovered.

Teresa,

Very well investigated - thank you. I was the first and only person on both sides of my family to be diagnosed with breast cancer, and my mercury exposure was significant.

Moms (and Dads) have your amalgam fillings safely removed. They are slowly poisoning you.

This is a well researched article. Mercury is still in the shots and it is a money making machine for the Drug Trust.

Teresa, very very interesting. Thank you so much for all your hard work and dedication. You are helping us all out tremendously!!! I'm still shocked at how us average parents can read this and understand it and can see how our children were harmed. Yet, the scientists and medical community ignore it.

I think one vaccine ingredient we don't hear much about is MSG. I remember reading about it at AoA awhile ago. They implicate MSG in alzheimers. MSG damages the hypothalamus.

I watched a wonderful documentary on YouTube called "The Beautiful Truth" and they talk about how damaging MSG is to the brain. It discusses the Gerson Therapy to cure cancer and how amalgams are poisoning everyone.

http://www.whale.to/a/msg.html
http://www.youtube.com/movie?v=wvzDHGLEUyw&feature=mv_sr

Fascinating and horrifying all at the same time. Apparently the drug companies (and Gorski aka Orac) have all the clues at their fingertips. Hmmm.

Mercury and breast cancer have also been linked due to this metal's endocrine disrupting properties, as you probably already know:

http://onlinelibrary.wiley.com/doi/10.1002/tox.20075/abstract

Theresa, wonderful job! I seriously am going to have to read this again to absorb and process your research. Not bad for a poor, defenseless, autism parent. ;)

Teresa

This is quite amazing. Recently, of course, I tried to pose the question to NIH director Francis Collins - also the question is fundamental to the programme of the Canary Party - as to why we were looking for cures without looking for causes as the population descended into chronic and possibly terminal ill-health, and this could not pose the issue more starkly. What is terrifying about this is how many of the answers may lie in science which has already been done but which has been quietly sidelined for certain purposes.

No doubt Gorski will rant and rage as usual.

John

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