Last Chance to Support XMRV/Autism Research!!!
An Open Letter to National Institutes of Health's Dr. Francis Collins: 54% of American Children Suffer from Chronic Health Problems

The Phoenicians: Autism Recovery Denial, Drug Profits and the Media’s Flat Earth

Phoenicians Py= P x Y Adriana Gamondes

Managing Editor's Note: We've run an updated version of this post by Adriana as a reminder of the current state of children's healthcare in America. Dismal. First, there was a new hire by Autism Speaks of a Pfizer Executive, which remains to be seen as either a godsend to deliver a new market to pharma or a route to real treatment for the myriad conditions associated with autism from behavior to GI problems to seizures.  I'm holding positive thoughts for the latter. Second there was this study, which says American Children are chronically obese and/or ill at a rate of over 50%. And third, a new movement is about to be introduced that calls for answers and action regarding the shabby state of childhood health in this country.

By Adriana Gamondes

What if the pharmaceutical industry had a formula for projected drug profits from a massive rise in autism? A formula such as:  PY=P×Y
And what if the same industry simultaneously rewarded scientists, media companies and organizations which disseminate the concept that there is no autism epidemic, that the rise is “false”, that the numbers have always been with us, but that there’s just increased diagnosis due to increased clinical and public recognition of autism? And what if this industry went on a massive campaign to proselytize the dangers of any treatment method—or any scientific authority— which threatened PY=P×Y?

Profiting from something while claiming it doesn’t exist isn’t anything new. According to some historians, the myth of the flat earth was perpetuated by the Phoenicians to prevent maritime trade rivals from voyaging to England to mine tin. Tin, which seems to have been scarce in ancient Canaan, was an essential ingredient to bronze; bronze was the essence of military power and trade at the time. Advantage in the tin trade gave the Phoenicians untold power.  As long as the lie held, Phoenician fleets regularly made mining expeditions north, trading freely with the natives of the British Isles—while neighboring states feared plummeting off the edge of the world if they dared to sail through the Straits of Gibraltar.

For the analogy, imagine the existence of the epidemic as “England”; autism recovery treatments as the “Straits of Gibraltar”; and maybe psychopharmaceutical drug profits as “tin”.

The epidemic-based profit formula actually exists. It was published in a 2003 study for Eli Lilly by researchers Robert and Julia Gerlai (HERE). From the study: Autism: a large unmet medical need and complex research problem

The question whether the epidemic status of ASD is due to true increase of incidence of the disease or simply its better detection and diagnosis is debated. Nevertheless, according to a most recent report to the legislature on the principal findings from the epidemiology of autism in California, the M.I.N.D. institute has confirmed that the increase of incidence is real and cannot be attributed to changes in diagnostic criteria or misclassification. Autism was estimated to have a frequency of more than 1 in 500 children, while more recent studies found its prevalence as high as 1 in 150 (for examples, see; also see CDC website  HERE). Researchers, private (e.g., Alliance for Autism Research), and government (e.g., National Institutes of Health, USA) agencies have recognized the enormous need. As a result, funding for research has significantly increased. Surprisingly, however, autism is still not among the neurological or neuropsychiatric diseases onto which large pharmaceutical research companies traditionally focus. This is unfortunate as ASD represents a significant unmet medical need with an enormous market size. Consider the following: ASD may be diagnosed as early as 2–3 years of age. Some even argue that successful diagnosis may be made at 8-12 months HERE) Autistic persons can live a normal life span. The market size can thus be calculated as follows: 


where PY is the number of “patient years,” P is the number of patients and Y is the number of years for which patients live after diagnosis. Calculating with the conservative prevalence estimate of 1 in 500, there may be approximately 600,000 ASD patients in the USA alone. These persons may live for an average of 76 years. Using the conservative age of 3 years for the time of diagnosis, PY may be calculated as follows.

PY=600,000×73=43,800,000, i.e., almost 44 million patient years.

To put this number into perspective, let us consider Alzheimer's disease, a disorder that is considered to represent the largest market by big pharmaceutical research companies. Calculating with P=9 million (say 15% of people above 65 years of age will have Alzheimer's disease in the Unites States) and Y=6 (Alzheimer's disease patients live, on average, for 6 years after first diagnosis), PY=54 million for Alzheimer's disease. The actual numbers may slightly vary. The number of Alzheimer's disease patients is actually smaller than 9 million but the disease may be diagnosed earlier and patients may live longer than for 6 years after diagnosis. On the other hand, the number of ASD patients can easily be twice or even three times higher than the presently estimated 600 thousand. Thus, it is clear ASD represents an unmet medical need that is comparable in order of magnitude to the largest neurological disease market, that of Alzheimer's disease. Thus, ASD should be of major interest to pharmaceutical research companies even when the 17-year patent expiration rule is considered.


[Update: Now listen to Pfizer’s (Geodon, Neurontin, Xanax, Zoloft, Chantix; through Wyeth merger, Effexor, Ativan, Pristiq, Prevnar) Robert Ring, newly partnered with Autism Speaks. echoing the title of the study (HERE ) . Of the partnership, Ring says, “This a real opportunity to really make a difference for a huge unmet need using expertise we’ve acquired over a number of years. In fact we’re working right now to build a pre-competitive consortium amongst our competitors, including Lilly (original manufacturer of thimerosal; maker of Zyprexa, Prozac, Cymbalta, Symbyax, Stattera), Roche (Valium, Klonopin, Tamiflu), Novartis (Ritalin, Tofranil, Trileptal; vaccines: Fluverin, Menveo), Janssen (Johnson & Johnson: Risperdal, Haldol), and trying to agree that this is an important population to be developing medicines for…”]

The study abstract was sent to me by Ben Hansen, a Michigan mental health activist and satirical blogger (Bonkers Institute HERE )Hansen was covered by the New York Times when his Freedom of Information Act inquiry of Michigan Medicaid turned up evidence that an Eli Lilly account executive may have influenced drug prescribing within the program, which had generated a 100% rise in child drug prescriptions in just 10 months. 

Just as  PY=P×Y denotes profit potential, for every child whose DAN-type biomedical treatments result in recovery or significant behavioral improvements and supplant the justification for psychoactive drugs, the formula also represents potential financial loss.
An email written by a friend and tireless warrior mother sums up precisely why non-psychopharmaceutical treatments for autism represent such a threat to industry:

“The medication nightmare began when we were so desperate to keep our son in a mainstream situation…we did not even have a computer.  He had no real functional language and was a runner. God help me I want a do over...We started down the psych. drug path— I can't even remember some of them, he reacted so badly to many and then he ended up on Risperdal, and the side effects from that led to the use of Cogentin, Lamictal, Prozac. I can't believe he could even stand up.  We honestly believed that these were going to fix the Autism. We were so uninformed. He is left with what is probably a permanent movement or tic disorder. We thought that Prozac was keeping this under some control but we backed him off of this as well.  The tic is no worse without it. Plus when we got him off of the Risperdal and all of the other crap, his language and cognitive awareness exploded! All the drugs were doing was sedating him. Being off of the Prozac has given him a sense of humor! It doesn’t just dull anger, or mood. It dulls ALL EMOTION! Once I was connected by a computer, to other parents and ARI in San Diego, things slowly began to change for us. Dr.Rimland actually spoke to me personally at least 4 times. We started the mega dose B vitamins, and fish oil,  and over [three year’s] time we got him off [all the drugs].There have been a few supplements that we have seen real change with. CoQ10 gave him curiosity! Magnesium, probiotics, zinc, VitC and epsom salt soaks have helped (but not eliminated) his constipation.”

As the original manufacturer of the mercury-based vaccine preservative thimerosal and the force behind Dick Armey’s addition of the “Lilly Rider” to the Homeland Security bill barring lawsuits against vaccine makers, Eli Lilly and Company is not exactly neutral on the issue of environmental causation for autism. Though the drug maker doesn’t currently manufacture vaccines, it maintains public lock step with vaccine manufacturers in terms of defending the “perfect safety” of vaccines and the “genetic” nature of autism. Eli Lilly funds such individuals as Dr. Bennett Leventhal (AofA Chicago Trib ;AofA Autism Speaks New Normal) whose response to the claim that the rise in autism rates represents a true increase was once “Rubbish!” (HERE).

Eli Lilly certainly has an interest in presenting the “increased recognition” theories, like those championed by GlaxoSmithKline grantee Eric Fombonne, for public consumption. If there’s an epidemic, and no epidemic can be solely genetic, then autism is environmental and this brings the magnifying glass too close to Eli Lilly’s ethylmercury-tainted door. 

Also, if there’s an epidemic and the condition is not genetic, then there’s hope for prevention and perhaps recovery.  As far as treatment is concerned, why would hopeful families tolerate the side effect profiles for certain psychiatric drugs when other, far safer remedies targeting or preventing the underlying mechanisms of autism and related conditions are available? Imagine another marketing formula in which H is the value of “effective treatment” + “prevention” and the sum is future autism drug profits. 


   HPY= goose egg

In terms of protecting industry’s interests, that just wouldn’t do. It would be better if the public were led to believe the “increased recognition/genetic” model of the disease. This is obviously for a host of reasons— a central reason being to protect vaccine manufacturers from litigation, and to protect their freedom to continue piling new combination shots and shots for diseases no one ever heard of onto an already overburdened schedule as old patents run out.

But, in the delicate words of Ronan Gannon, GlaxoSmithKline’s executive director of US marketing and member of the National Vaccine Advisory Committee’s financing working group, the pharmaceutical drug market “dwarfs” the vaccine market. The global vaccine market was estimated at more than $20 billion last year with surges from Gardasil and the H1N1 scare. Psychiatric drugs top $40 billion in annual sales in the US alone.

As far as autism’s impact on the psychopharm market, considering the following:

•  Psychopharmaceutical sales for the treatment of autism are currently at $3.5 billion a year, largely for the US market, representing 7% of the overall $40 billion yearly psychopharmaceutical sales for 1% of the child population BusinessWeek).

• The Lilly study enthusiastically projects that autism could eventually reach “Alzheimer’s” rates. Alzheimer’s rates are reported to be doubling every twenty years. 

• A significant percent of the 40 fold rise in pediatric bipolar disorder could be due to sub-autistic toxic injuries (another portion would be due to the drugs being prescribed to children themselves: mania is a listed side effect of all classes of psychotropes. See Sharna Olfman’s “Bipolar Children”, chapters by Healy, Whitaker and Landrigan respectively, HERE).

• Children diagnosed with bipolar disorder are frequently prescribed the same drugs as children with autism, particularly the newer, on-patent antipsychotics, though many are being treated with autism recovery methods.

• Sales of atypical antipsychotics went from $0 to $16 billion a year since the start of the epidemic. 

Bearing in mind that vaccine litigation potentially represents a corporate-wrecking proverbial last straw, we have our pick of motives for industry’s perpetuation of the “genes-only/always been with us/no cure/no epidemic” rhetoric.

But the “bend sinister” is that, at the same time, acknowledgement of an epidemic in certain circles could enliven the psychopharmaceutical drug market. While some people might have thought that National Institute of Mental Health director Thomas Insel’s recent softening on environmental contributions to autism and admission that the rise is real (HERE ) meant he might eventually concede to vaccine causation, I just assumed he was boosting investor confidence.

Thomas Insel, brother of a vaccine maker, chairman of the Interagency Autism Coordinating Committee (IACC) who stealthily voted vaccine safety research off the agenda and, under whose oversight, the NIMH’s website on autism went from mentioning a few drugs by generic name in 2006 to presently promoting 15 psychiatric drugs by brand and five more by generic name—the man under whose direction IACC consistently leads all its published recommendations with promises to create more psychopharmaceutical drug algorithms for autism—is not interested in holding pharmaceutical companies to account. He’s unlikely to be interested in promoting non-psychotrope treatments for the underlying causes of autism.  If anything, we may see him cheerleading research for—God forbid— an “autism vaccine”. 

Thomas Insel is merely following the tradition of his post. For decades, the National Institute of Mental Health has been under heavy criticism for being a “captured” agency which acts chiefly as PR wing to psychopharmaceutical manufacturers. Several NIMH leaders have gone on to either lucrative industry careers or lucrative symbiosis. Frederick Goodwin, former head of the NIMH (and front group ACSH advisory board colleague of Paul Offit and Steven Novella, HERE ) lost his NPR show “The Infinite Mind” when he was caught taking $1.3 million in supposedly undeclared fees from GlaxoSmithKline to promote drugs like Paxil and Lamictal on the air. Other examples of the “NIMH-Big Pharma “revolving door”, as clinical psychologist Bruce E. Levine put it (HERE ), include Lewis Judd, former NIMH director, who joined the scientific advisory board of Roche Pharmaceutical in 2001 (Klonopin, Valium, Tamiflu); and Steven Paul, scientific director of NIMH, who left to become vice president of Eli Lilly in 1993 (Prozac, Zyprexa, Cymbalta, Strattera, Symbyax).

It’s not a matter of whether Thomas Insel will land at a pharmaceutical company once he leaves his agency, but a question of which one.

It would be a different story and we’d be living in a different world (one in which childhood vaccines in the US would have been safer and fewer; maybe one in which the epidemic never happened) if the “autism remedies” being presented by pharmaceutical companies were in any way effective towards underlying disease mechanisms. But the idea that psychiatric drugs correct anything in the brain has been repeatedly debunked. In fact, to date, other than dabbling in prenatal vitamins, etc., Big Pharma simply can’t compete with recovery treatment models—not fairly, in any case.  They won’t try either. Developing treatments which work by targeting vaccine injuries is out of the question. And research and development costs for such treatments go far beyond pharma’s traditional investment bounds.

That doesn’t mean pharma won’t occasionally follow the cues of autism recovery research, but in the hands of many drugs companies, anything can become a weapon: following the discovery that glutamate feedback may be disrupted in schizophrenia and autism (interesting that both mercury and the antiseizure drug Depakote—a rare, known cause of autism—induce glutamate feedback disruption), drug companies rushed to find chemicals with sedating properties which could be shown to do something to glutamate—so that the drug could be called a “targeted treatment”—though it would not necessarily do anything therapeutic to the “target”. No matter though—whatever the drug did do could be spun as clinically beneficial, as has been done for antidepressants and other classes of psychotrope (easy to pull off because, for one example of lab spin, the testing methods used in killed-animal drug studies cannot distinguish between DNA synthesis in the brain which occurs as a part of supposedly beneficial neurogenesis—cell division and proliferation— and DNA synthesis which occurs as a part of cell death, but the FDA looks the other way). Once researchers found a likely candidate—in this case, variations of a “metabotropic glutamate agonist antipsychotic” (HERE )— companies lined up for FDA approval  . A small hitch in the approval process has been that glutamate agonists appear to have an even higher level of lethal neuroleptic malignant syndrome than either first or second generation antipsychotics (HERE). Nothing a little spin and a lot of cash can’t fix.   

Antipsychotics—the main drug class being pushed for autism— were originally brought to the American market for a mere $30,000 research investment. Far more funds were spent on heavy lobbying of government agencies and the press to promote the drugs as a miracle cure which would liberate mental patients from institutions once and for all. Instead the opposite happened. As journalist Robert Whitaker documented in his book, “Mad in America”, an eight year World Health Organization study performed in the 1960s and 70s (the International Pilot Study, (scroll down to C. HERE) found that outcomes for schizophrenia were three times worse in developed countries which relied primarily on the use of neuroleptics to treat the condition when compared to outcomes in a range of culturally heterogeneous underdeveloped countries which rarely employed the drugs.

In other words, in underdeveloped/developing countries, schizophrenia was known—as impossible as that may seem in the US— as a disease with more than a 60% chance of recovery. In developed countries, the reverse was true. The WHO conducted a more surgical follow-up study in response to protests by organized psychiatry, but the original findings were only reiterated.

Although— unlike autism—schizophrenia is sometimes distinguished as a grab-bag diagnosis (misdiagnosed due to racism, or out of cultural or medical incompetence), the degree to which schizophrenia shows itself to be, like autism, an environmentally or toxically mediated condition affecting a subset of susceptible individuals may account for the lower incidence of schizophrenia (at least in the 1960s and 70s) in less industrialized countries. But the WHO five year follow-up to the International Pilot study firmly demonstrated that severity of onset within agreed-upon parameters of the condition was not the determining factor in recovery rates. This hints that, whereas non-drug environmental factors could have triggered the condition in some, drugging rates almost certainly effected outcomes. The rates of relapse and direness of outcomes were in direct proportion to the percentage of patients in developed countries who were chronically exposed to the drugs, with the Soviet Union “winning” the distinction of worst outcomes with a drugging rate of 85%.

The US now drugs the growing population of patients with schizophrenia at a rate of more than 93%; outcomes and relapse rates have worsened accordingly. Other countries have been catching up as well, so that the pool of undrugged schizophrenics is shrinking globally (HERE)  In fact, schizophrenic patients have been drugged at such a pace in the past fifty years that most clinical and public concepts of symptoms and outcomes reflect the drugged condition, not the condition itself. For instance, schizophrenia’s clinical association with violence—which was not strictly associated with the disease process 100 years ago— increased with drugging rates. The same may prove true for autism.

The toxicity of the drugs and their capacity to induce or worsen environmental brain injuries shouldn’t be that surprising. Early psychiatric drugs were often derived from various industrial pigments and solvents (imipramine, for example, was once an industrial dye called “Summer Blue”). Neuroleptics in particular have a questionable history. The drugs were originally used to deliberately induce Parkinsonism, under the idea that Parkinson’s was somehow antithetical to psychosis. Those with advanced Parkinson’s disease—so the thinking went— generally don’t show any emotion at all, much less the throws of psychosis.
The dopamine theory still used in marketing antipsychotics was concocted after the drugs had been put into wide use in institutions, and has about as much basis as the “genetic brain chemical imbalance correction” theories used to market antidepressants today (HERE). It was originally thought that neuroleptics “worked” (at least initially and only when they did) to reduce psychotic episodes by inhibiting dopamine in the brain on the theory that dopamine levels “flared” during psychotic episodes. That concept never bore out in actual research though: measured dopamine levels could be high, low or indifferent in patients enduring psychotic incidents. Even according to industry’s own dopamine theory, neuroleptics don’t “work” in the end because the brain swelling unilaterally seen within weeks of exposure to antipsychotics turned out to be caused by drug-induced mass  generation of dopamine receptors, causing the brain to become super-sensitive to the very brain chemical that was assumed to be inducing psychosis to begin with.

Few are aware that neuroleptics are often used as solely physical painkillers for certain conditions. It’s been speculated that the drugs initially “reduce disruptive behavior” in some (not all) in the “honeymoon” phase of drug treatment by partly acting as global, emotional-physical painkillers. Sadly, the very painkilling properties of many psychiatric drugs could partly hinge on their capacity to kill brain cells: the sensation that apparently comes with mass brain cell death, as in glue sniffing, is euphoria. This is relevant to autism in that many children with autism, for instance, live with chronic pain from inflamed GI tracts and other physiological injuries which can affect behavior, socialization, cognition. Within reason and depending on the health costs of using certain agents, temporary painkilling could be viewed as having at least partial clinical value.

But doctors can not only lose their licenses for overprescribing painkillers, they can go to jail, so the painkiller distinction does not serve the industry financial platforms of overprescription, overmarketing and “polypharmacy—the practice of adding new drugs to quell side effects of previous drugs,  ad infinitum (ad nauseum, ad mortem). This leads to the need for false clinical “correction” theories for certain drugs.
Painkillers also can’t be mandated. Does anyone wonder what happens to the scores of children with autism who are currently being arrested in schools for exhibiting behaviors associated with the disability?  Many are routed to “psychiatric courts” where treatments are decided by judges (HERE).Those “treatments” tend to fall in line with National Institute of Mental Health guidelines. The mandated drugging of people in institutions and correctional facilities, and among children in foster care (those drugged against parental consent) and remanded juvenile offenders represents a good slice of drug profits.

In any event, the distinction of “neuroleptics as painkillers” only holds until the side effects kick in.  The current generation of antipsychotics— the “atypicals” once marketed as an improvement over the “old”, “bad” drugs like Thorazine—are nearly identical to older neuroleptics in terms of side effect profiles. Atypicals, like the older generation of drugs, have the capacity to induce agonizing and lethal conditions such as tardive dyskinesia, respiratory dyskinesia (often labeled “asthma”, “COPD”, etc.), tardive dementia, tardive psychosis, lethal cardiometabolic disorder, organ failure, GI disorders, mass brain cell death, diabetes, dystonia, suicide, gynecomastia, violence (especially on withdrawal) and much more. Current antipsychotics still induce Parkinsonism: the “flat” emotional affect—a primary, not “side”, effect of the drugs—is merely a “larval” phase of the condition.

Antipsychotics—old and new—also induce lipid metabolism, demyelinating and mitochondrial disorders which either mimic various genetic conditions (like Neimann-Pick’s), or which fully add up to conditions previously thought to be solely genetic such as MELAS (Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes). MELAS shows certain lab findings which overlap with autism.

In patients who take them, regardless of observable manifestation of side effects, neuroleptics induce or increase the appearance of certain proteins in cerebrospinal fluid which are markers for Alzheimer’s and dementia. These proteins— APO-D or apolipoprotein D— are abnormally elevated to some degree in those with autism, schizophrenia and Alzheimer’s who were never exposed to neuroleptic drugs. But after treatment with antipsychotics, the levels of APO proteins among schizophrenics and Alzheimer’s patients were shown to rise considerably. So here is evidence that neuroleptics actually make some of the clinical dysfunction underlying schizophrenia and Alzheimer’s worse—and it’s not unreasonable to predict this might also be true for autism.

Making conditions worse isn’t a great PR tagline for drug corporations. Insofar as industry does not wish for its drugs’ side effects to be widely understood, it also won’t tolerate the compounded menace of autism recovery science. Autism recovery science doesn’t just point to vaccine/environmental cause or pose safer and actually effective treatment options which result in direct treatment competition for pharma’s blockbuster drugs. Autism recovery science also—by incidentally corroborating the overlaps in types of brain damage induced by both vaccines and psychopharmaceuticals—potentially threatens PY for every cognitive, behavioral or psychiatric condition targeted by drug makers.

Furthermore, just as the existence of an unvaccinated population is threatening to industry because it provides the study “control” for comparison of injury rates, a drug-naïve population of children with autism provides a clearer picture of just which cellular processes are being disrupted and what might be causing the disruptions to begin with. Just as important, the existence of a drug-naïve population also spoils the pretense that adverse drug effects are attributable to autism itself—a “misattribution of contingency” that’s been played with nearly every drug side effect since “mental health” drugs were first marketed.
 The fact that children within the autism recovery community have such low psychiatric drugging rates when compared to the 70% of developmentally disabled children in the general population is a threat that won’t be allowed to stand without a fight. As psychopharmaceutical expert Dr. Grace Jackson argues in her most recent book, “Drug Induced Dementia: The Perfect Crime” (HERE), distinguishing what underlies certain forms of behavioral disorders—whether these conditions are genetic or environmental, preventable or treatable— becomes more and more difficult as drug exposure increases and skews the evidence. 

Dr. Jackson, not incidentally, describes herself as a “big fan” of Dr. Andrew Wakefield’s “elegant” theory. Her book is the source for the above information on drug-induced mitochondrial dysfunction, lipid storage disorders and biomarkers for dementia. In 2007, I saw her present a case study of a typical seven year old boy who developed severe symptoms of autism when exposure to the drug Depakote compounded asymptomatic brain damage and mitochondrial dysfunction from chemotherapy treatment several years earlier. For an example of evidence-skewing, according to Dr. Jackson’s research, valproic acid apparently has a dozen or so overlaps with the effects of thimerosal and other vaccine toxins on the brain, including elevated serum ammonia, lipid metabolism damage, evidence of Alzheimer’s Type II astrocytosis; tubulin, glutamate, glutamine and carnitine disruption; myelin damage, alteration of cytokine activity and mitochondrial damage.  During the Autism Omnibus, a government attorney admitted that pre or neonatal exposure to Depakote could cause autism. Aside from his excessive confidence in stating age limits of exposure, the attorney’s statement was backed up by a 2008 study (HERE).

As long as independent researchers can still differentiate the source of damage from one agent to another, the crime will not be perfect. The FDA helps to obfuscate these imperfections by making the statistical evidence of damage from drugs—which is supposed to be readily available through its Medwatch database—notoriously difficult to access. Add this to the fact that only about 10% of all adverse drug events are ever reported to Medwatch, and any search for injury and death statistics is a miserable procedure.

Fortunately, an activist and database programmer named Steven Helgeson figured out how to untangle the FDA Adverse Events Reporting System. He created a searchable site for the purpose of consumer education (HERE).

A quick search of the database by drug class, brand or generic drug name brings up the question of whether “death” is a particularly good selling point for drug corporations. As the autism recovery community finds itself, its doctors and information resources under increasing attacks by media and industry for advocating “dangerous” non-psychoactive treatments for autism,  it’s interesting to note that the full dangers of the most common mainstream “treatments” for autism—the very drugs frequently recommended by the industry “experts” these media sources quote— are never mentioned. 

In fact, while the mainstream media in the UK and US might protest the excessive drugging of certain populations deemed not to “need” the drugs (note the title of the Chicago Tribune article: “Psychotropic Drugs Given to Nursing Home Patients Without Cause”, HERE ), the same outrage is absent when it comes to the deadly drugging of more “disturbing” populations, such as those with autism and schizophrenia. This disconnect on drugs is a media tradition: in the 1970s, the same publications which decried the use of neuroleptics as a form of torture against Soviet dissidents showed only contempt for the struggle of the “Mad Rights” movement to ban forced drugging in institutions. That members of the media may love grandma and despise designated foes of Democracy is not proof of principled reporting—only that the shape of reality may vary according to agenda and the perceived expendability of certain human beings. 

We’ve all seen the repeated coverage of the tragic and avoidable death of Tariq Nadama in news items denouncing the dangers of autism recovery treatments. Tariq was given the wrong chelator (HERE ), for which his parents rightfully sued the physician responsible. There have been two other reported deaths from hypocalcemia as a result of the same medical mistake in the past seven years, though only the Nadama case involved a child with autism.

Using Steve Helgeson’s Medwatch-decrypting database, below is a list of US deaths due to just some of the drugs promoted on the NIMH autism website within a four year period. Helgeson reports that some of the cases of death associated with individual drugs were left out due to being listed irregularly on Medwatch, therefore the numbers below are conservative. 

Number of deaths by drug between 2004 and 2008:

Risperdal : 308: Abilify: 213: Zyprexa: 417; Geodon: 140;  Haldol: 46; Prozac: 371; Celexa: 411; Zoloft: 356; Luvox: 15; Anafranil: 16; Valium: 269; Ativan: 109; Ritalin: 76

The above death statistics include death by suicide, homicide, prenatal/neonatal death and “other”, such as drug-induced cardiac arrest, stroke, organ failure, etc.

Some might take exception to the use of suicide stats in the overall numbers, even though suicide statistics are far higher for those on the drugs than among unexposed patients with the same conditions. Objections are usually based on yet another goofy industry theory which sounds like something extemporized by a tween. It’s called “roll-back”. The idea goes something like this: people who are depressed don’t have enough energy to kill themselves but, when first taking antidepressants or other psychotropes—before the supposed “anti” part kicks in—the drugs perk them up enough to carry out their preexisting suicide plans.

The roll-back hypothesis doesn’t explain the sudden mania, violence and suicides among people given the wrong drug by pharmacy mistake (i.e., Xanax instead of Zantac; Celexa instead of Celebrex), and those without psychiatric or violent histories who take the drugs for nonpsychiatric purposes (temporary insomnia, etc.). And, as Grace Jackson asks rhetorically in her first book, “Rethinking Psychiatric Drugs”, how much energy does it take to perform the easiest form of suicide going—the intentional overdose?  The theory is stupid, really, and the drugs are known to induce a condition called akathisia, which can range from “restlessness” to a sense of profound inner torture (HERE). Anything which potentially induces akathisia-like psychosis— such as the antimalarial Lariam, the anti-viral Tamiflu, and all classes of psychoactives to varying degrees— can induce violence and suicide. Many of the suicides and homicides we hear about in the news involving children in general and children with autism also involved psychiatric drugs (HERE).

Though he says he’s working on it, deaths by anticonvulsants and “mood stabilizers” are not included in Helgeson’s database yet.  According to another breakdown of the FDA AERS website, a total of 1,601 deaths are listed for “other” psychoactive drugs between 2004 and 2006 (two years less than the software’s search period), among 6,907 reported deaths from all classes of psychopharmaceuticals.

6,907 in two years. That’s two 9/11’s or the equivalent of 27 to 28 fully-loaded Boeing 737s dropping out of the sky every year. Since the reported statistics are estimated to be only one-tenth of the actual toll, imagine 69,070 deaths every two years—that’s 278.5  737s fatally crashing to the ground year in, year out.  

Every drug war has its casualties. For another analogy, pharma makes Ciudad Juarez look like a resort town. This seems more the case now that the Supreme Court has approved unlimited campaign contributions by what are frequently international corporate conglomerates. The cartels control everything. 

In response to my emailed remarks over the Chicago Tribune’s pre-Thanksgiving hit piece on autism recovery proponents, scientists and treatments (“Autism treatments: Risky alternative therapies have little basis in science”), Trine Tsouderos sent me the stock reply that everyone else got, except for one little addendum:

Thank you for your note.
I am sorry we cannot agree on the issue, but we stand by our conclusions, which  are based on exhaustive research and talking with some of the most highly regarded, best-credentialed experts in the field. I can assure you GlaxoSmithKline did not have anything to do with these articles.
Best wishes and hope you and your family have a lovely Thanksgiving, Trine

She can’t fool me. There’s no Thanksgiving in Juarez. My initial email to Tsouderos remarked on the two Glaxo ads which appeared next to her online article.

Now can anyone guess which psych drug wins the distinction of highest death count according to the FDA’s Medwatch database? GSK’s antidepressant Paxil. With a once-a-day price tag of over $1,500 a year, Paxil racked up 1,139 reported deaths in a four year period. GSK also has a glutamate-targeting antipsychotic in the pipeline, and is the maker of Tagamet and other “tummy” meds that children within the vaccine injury movement no longer seem to use to any great degree.

GlaxoSmithKline is the maker of the British MMR and more than 25 other vaccines for the global market, including H1N1, seasonal flu, human papillomavirus and the Engerix B vaccine which contained thimerosal up to 2007 and which—when compared to other Hepatitis B vaccines— was associated with the highest incidence of CNS inflammatory demyelination (HERE). 

GSK also makes the anticonvulsants Keppra, and the blockbuster dual anticonvulsant/sixth-highest-selling antipsychotic Lamictal, with a once-a-day price tag of $1,883 a year. Since Lamictal is not yet listed on Steve Helgeson’s search site, we can only wonder how many of the 1,601 deaths from “other drugs” indicated on Medwatch were due to the use of Lamictal as an antipsychotic. I have to differentiate this from Lamictal’s use as an antiepilepsy drug, both because deaths of children who suffer from seizure disorders would generally not make the FDA drug-death roster (seizures become the alibi for almost any cause of death); and because I know that parents who give these drugs to children for severe seizures have no choice. The death toll among children with seizures and autism is generally attributable to “autism” itself as the rate of deadly seizure disorders among vaccine injured children rise every year.

This obviously wasn’t factored into Eli Lilly’s profit formula. Many children with autism don’t make it to age 9, much less age 76. Add to this the predictable death toll from psychopharmaceuticals, and it looks like PY=P×Y might need retooling.

I think it’s as cruel to judge parents cornered into drugging children who try to gouge out their own eyes and gnaw off their fingers as it is to judge parents forced to use anticonvulsants to keep vaccine-induced seizures from killing their children. For one, once in, it’s murder to get out: withdrawal from these drugs is often extraordinarily dangerous. And though the drugs themselves can induce self-injury, obsessive behaviors and violence, some children with autism intractably self-mutilate prior to drug exposure.  I have friends who live under these shadows and I sometimes open emails from them like I’m pulling crime scene tape off their doors. I never know when the worst of all possible news might come. But no one hates these medications more than those forced to use them at gunpoint, and who know perfectly well that these drugs are often manufactured by the very companies marketing the vaccines which robbed them of their once healthy children.  

In any case, Paul Offit—eight figure vaccine profiteer, PR capo, epidemic denier— put it well when he said that hope is “dangerous”.  He’s right, it is. He actually indicated “false hope”, but false to him is real enough to many and the meaning is clear considering what’s at stake for all concerned.  It’s politically dangerous for scientists and families to provide or pursue hope because this can only be done by exposing cause. Even success brings home the horror of what’s been lost by showing that it never had to happen to begin with. And hope undeniably represents dire straits for unregulated industry. 

Because industry can’t and won’t compete with this:

they give us this:  

Nohopetal Adriana Gamondes

Adriana Gamondes is an Age of Autism contributor and one of our Facebook administrators. She lives in Massachusetts with her husband and recovering twins.


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Hi Benedetta,

You're not asking much at all. My suspicions started when my mother began her descent into Alzheimers about 5 years ago. There was absolutely no history of Alzheimers, or any other form of dementia in her family. It made no sense, especially since she only recently turned 70. So this past summer I got a list of her medications, and looked up the side effects for each one (there were 5 at that time). Of the side effects listed for the statin, which coincidentally was added around 5 years ago, the following two stood out the most:

- Some people experience memory loss, report an inability to concentrate, and feel that they are developing Alzheimer’s disease when taking statin drugs.

- Symptoms of muscle damage (unexplained muscle pain, tenderness or weakness)

Needless to say, this peaked my curiosity and I started to research it more deeply. I've found many resources since, but two of the better summaries that I have found are the following:

1. From Dr. Joseph Mercola: ( )

This article is quite helpful in and of itself, but it also offers a free download which contains even more information on the subject

2. From Dr Duane Graveline: (

The above link is one of the better summaries, but he has written extensively about statins and the associated health risks. Dr Gravelines is a former USAF Flight Surgeon, NASA Astronaut, and retired family doctor who has a personal connection, in that he too suffered devastating side effects from statin drugs that were prescribed for him


Thanks for the updates to this on-target and powerful essay.
People need to know just how much and how often pharmaceuticals are not the best solution or indeed any solution at all. It was particularly good to watch Daniel's recovery video.

Reading the comments here, I keep thinking of the 1980s ad..."This is your brain (uncooked egg). This is your brain (egg now sizzling and scorching) on drugs..." I don't think the neurological health of the U.S. improved with the "War on Drugs."


Barry, my Dad has been on statins every since his heart attack 12 years ago. He cannot pick up his feet,shuffles, they think it is Parkinson's, but his hands do not shake.

I know this is asking alot, but can you give me some places where you got some of this information.


Sue Morgan Wrote: "... Why, pray tell, are Alzheimer's rates doubling every 20 years? Wow, do you think it could be all those flu shots they keep pushing on the elderly??...."


Flu vaccines are definitely part of the equation, given all the mercury and aluminum they contain. But I think another culprit in the Alzheimer’s epidemic is big pharma's ... other recent bonanza, which are the scandalously over prescribed statin drugs.

You can't even live without cholesterol, and studies have long associated poor mental function (..and memory) with low levels of cholesterol. Statins are believed to work by inhibiting the livers production of cholesterol. But what most people don’t realize is that stains also keep the BRAIN from making the cholesterol that it requires.

The blood brain barrier stops cholesterol in the blood from entering the brain, but it does allow statins to pass through and subsequently inhibit the brains production of cholesterol. Depriving brain cholesterol has a direct effect on the release of neurotransmitters, and since neurotransmitters affect data-processing and memory, it's hardly a surprise that declining cognitive function is such a commonly reported complaint from stain users, and/or their caregivers.

Another side effect of statins, considered by many doctors as just another part of Alzheimers, is the altered posture and gait. This side effect is cause by yet another liver function that stains inhibit, which is the synthesis of Coenzyme Q 10, a molecule that is crucial to the function of every muscle cell in the body.

Some of the rare, more enlightened doctors actually started to see this for what it is, and have even started to refer to it as the "Statin Shuffle".

Media Scholar

Vaccines for preventing influenza in healthy adults

Our results may be an optimistic estimate because company-sponsored influenza vaccines trials tend to produce results favorable to their products and some of the evidence comes from trials carried out in ideal viral circulation and matching conditions and because the harms evidence base is limited..


"But no one hates these medications more than those forced to use them at gunpoint, and who know perfectly well that these drugs are often manufactured by the very companies marketing the vaccines which robbed them of their once healthy children. "

You said it SISTER! I have to pay them for the damage they have done in the first place for as long as my daughter lives.

She also uses Lamitcal too - I suspect seizures in her sleep cycle.

I will have to re read this again, because I had to go through it to quickly,I am being rushed as usual for one of my sick ones. Right now it is my daughter she is on Seroquil for bipolar and she wants someting sweet because it makes her crave sweet things. Sugar and high carbs are notallowed with an acquired mitrochondria cytopathy. And So I am going to make her a Dr. Atkin's Sunshine Cake.


Maybe someone should ask Pfizer if they're working on a vaccine for autism. Don't laugh - yet. There are trials starting on a vaccine for asthma: It's called a "DNA vaccine," of all things! If they can do that for asthma, then how about autism? Huge market, right? But if not, why not? (Tee-hee!)

Sue Morgan

Why, pray tell, are Alzheimer's rates doubling every 20 years? Wow, do you think it could be all those flu shots they keep pushing on the elderly??

Gayle Provost

I have a 3 year old diagnosed with Autism and a 2 year old who is diagnosed with Aspergers. We recently went "full steam" with biomedical treatment and have been seeing amazing results! (My son is progress is nothign short of a miracle!) We decided a while ago that we would never use prescription medications on our children, we know there is another path we can take. Thank-you for this article. It not only validates our decisions but it also gives us a TON of hope. Thank-you to all the "warriors" out there for all the work you do and we are proud to join the ranks! Thank-you!!!!!!!


Candace-- Thank you. I'm so sorry to hear about the loss of your son's dad and so recently. Hoping you're all holding up and hoping there was comfort in seeing his son turn around so dramatically. Thank you also for sharing that phenomenal story about your son's recovery. Blessings.


wow!!! great i will pass around..and face book..i also have a son 13 who is recovered by natural cures tons of love and so much hard work...we just lost my sons dad age 47 a few weeks ago to a aggressive cancer..see rons victory..we also used alternative treatments..this is good information..we definetley need to move away from pharma-spoon feeding us...they damaged a generation of children...we must not continue to let that repeat...candace

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